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Epigenetic maintenance strategies after allogeneic...
Journal article

Epigenetic maintenance strategies after allogeneic stem cell transplantation in acute myeloid leukemia

Abstract

Acute myeloid leukemia (AML) is an aggressive blood malignancy characterized by the accumulation of immature blood cells that can severely impede the normal functions of the hematopoietic system. AML still has a poor 5-year survival rate of around 30%, and efforts to develop novel targeted therapies have been met with challenges. Allogeneic hematopoietic stem cell transplantation represents a potentially curative treatment for many AML …

Authors

Yan Y; Upadhyaya R; Zhang VW; Berg T

Journal

Experimental Hematology, Vol. 109, , pp. 1–10.e1

Publisher

Elsevier

Publication Date

5 2022

DOI

10.1016/j.exphem.2022.03.003

ISSN

0301-472X