Inferior outcomes for overweight children undergoing allogeneic stem cell transplantation Journal Articles uri icon

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abstract

  • SummaryThis retrospective cohort study aimed at determining whether overweight children undergoing allogeneic stem cell transplantation (SCT) had inferior overall survival compared with children who were not overweight. Children ≥2 years of age who received allogeneic SCT were included. Overweight was defined as a body mass index ≥ 95th percentile; 54/325 (17%) children were overweight. Overall survival at 5 years was significantly inferior at 46·6 ± 7·3% in the overweight group compared with 59·5 ± 3·2% in the non‐overweight group (P = 0·02). Our study demonstrated that overweight children who undergo allogeneic SCT had inferior survival compared with children who were not overweight.

authors

  • Bulley, Sean
  • Gassas, Adam
  • Dupuis, L Lee
  • Aplenc, Richard
  • Beyene, Joseph
  • Greenberg, Mark L
  • Doyle, John J
  • Sung, Lillian

publication date

  • January 2008