AMP-Activated Protein Kinases Concept

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• AMP-Activated Protein Kinase Regulates GLUT4 Transcription by Phosphorylating Histone Deacetylase 5  Academic Article
• AMP-Activated Protein Kinase-Regulated Activation of the PGC-1α Promoter in Skeletal Muscle Cells  Academic Article
• AMP-activated protein kinase (AMPK) beyond metabolism  Academic Article
• AMP-activated protein kinase (AMPK)  1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise  Academic Article
• AMP-activated protein kinase at the nexus of therapeutic skeletal muscle plasticity in Duchenne muscular dystrophy  Academic Article
• AMP-activated protein kinase is required for exercise-induced peroxisome proliferator-activated receptor γ co-activator 1α translocation to subsarcolemmal mitochondria in skeletal muscle  Academic Article
• AMP-activated protein kinase — the fat controller of the energy railroadThis paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference.  Academic Article
• AMP-activated protein kinase, fatty acid metabolism, and insulin sensitivity  Academic Article
• AMP-activated protein kinase: the current landscape for drug development  Academic Article
• AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging  Academic Article
• AMPK and the endocrine control of energy metabolism  Academic Article
• AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism  Academic Article
• AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatment  Academic Article
• AMPK in Health and Disease  Academic Article
• AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice  Academic Article
• AMPK promotes macrophage fatty acid oxidative metabolism to mitigate inflammation: implications for diabetes and cardiovascular disease  Academic Article
• AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity  Academic Article
• AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis  Academic Article
• AMPK β1 reduces tumor progression and improves survival in p53 null mice  Academic Article
• AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation  Academic Article
• AMPK-Dependent Inhibitory Phosphorylation of ACC Is Not Essential for Maintaining Myocardial Fatty Acid Oxidation  Academic Article
• AMPK-dependent hormonal regulation of whole-body energy metabolism  Academic Article
• AMPK-independent pathways regulate skeletal muscle fatty acid oxidation  Academic Article
• AMPK: mediating the metabolic effects of salicylate-based drugs?  Academic Article
• Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models  Academic Article
• Adiponectin primes human monocytes into alternative anti-inflammatory M2 macrophages  Academic Article
• Adiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed rats  Academic Article
• Adiponectin: Starving for Attention  Academic Article
• An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice  Academic Article
• Are SIRT1 activators another indirect method to increase AMPK for beneficial effects on aging and the metabolic syndrome?  Academic Article
• Bradykinin stimulates endothelial cell fatty acid oxidation by CaMKK-dependent activation of AMPK  Academic Article
• Brief intense interval exercise activates AMPK and p38 MAPK signaling and increases the expression of PGC-1α in human skeletal muscle  Academic Article
• CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK  Academic Article
• Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humans  Academic Article
• Cellular Energy Sensing and Metabolism—Implications for Treating Diabetes: The 2017 Outstanding Scientific Achievement Award Lecture  Academic Article
• Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle  Academic Article
• Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle  Academic Article
• Cigarette Smoke Exposure Triggers the Autophagic Cascade via Activation of the AMPK Pathway in Mice1  Academic Article
• Ciliary Neurotrophic Factor Suppresses Hypothalamic AMP-Kinase Signaling in Leptin-Resistant Obese Mice  Academic Article
• Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress  Academic Article
• Contraction-induced skeletal muscle FAT/CD36 trafficking and FA uptake is AMPK independent  Academic Article
• Contraction-related stimuli regulate GLUT4 traffic in C2C12-GLUT4myc skeletal muscle cells  Academic Article
• Controlling skeletal muscle CPT-I malonyl-CoA sensitivity: the importance of AMPK-independent regulation of intermediate filaments during exercise  Academic Article
• Cytokine Regulation of AMPK signalling  Academic Article
• Diminished contraction-induced intracellular signaling towards mitochondrial biogenesis in aged skeletal muscle  Academic Article
• Editorial: “Presenting” an adaptive role for AMPK  Academic Article
• Emerging Role of AMPK in Brown and Beige Adipose Tissue (BAT): Implications for Obesity, Insulin Resistance, and Type 2 Diabetes  Academic Article
• Energy-stress-mediated AMPK activation inhibits ferroptosis  Academic Article
• Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662  Academic Article
• Establishing a relationship between prolactin and altered fatty acid β-Oxidation via carnitine palmitoyl transferase 1 in breast cancer cells  Academic Article
• Evidence for the role of AMPK in regulating PGC-1 alpha expression and mitochondrial proteins in mouse epididymal adipose tissue  Academic Article
• Exercise-induced Protein Arginine Methyltransferase Expression in Skeletal Muscle  Academic Article
• Exercise-stimulated interleukin-15 is controlled by AMPK and regulates skin metabolism and aging  Academic Article
• Exercising women throw a wrench in the gears of the AMPK-lipid oxidation link  Academic Article
• Fish oil supplementation suppresses resistance exercise and feeding-induced increases in anabolic signaling without affecting myofibrillar protein synthesis in young men  Academic Article
• Genomic and Metabolic Preparation of Muscle in Sockeye Salmon Oncorhynchus nerka for Spawning Migration  Academic Article
• Glutamate increases glucose uptake in L6 myotubes in a concentration- and time-dependent manner that is mediated by AMPK  Academic Article
• Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity  Academic Article
• High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus  Academic Article
• Hyperglycemia-Driven Inhibition of AMP-Activated Protein Kinase α2 Induces Diabetic Cardiomyopathy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes In Vivo  Academic Article
• IL-6 is not essential for exercise-induced increases in glucose uptake  Academic Article
• Immunometabolism of AMPK in insulin resistance and atherosclerosis  Academic Article
• Increased skeletal muscle glucose uptake by rosemary extract through AMPK activation  Academic Article
• Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release  Academic Article
• Interactions between ROS and AMP kinase activity in the regulation of PGC-1α transcription in skeletal muscle cells  Academic Article
• Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase  Academic Article
• Intermittent and continuous high-intensity exercise training induce similar acute but different chronic muscle adaptations  Academic Article
• Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells  Academic Article
• Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells  Academic Article
• Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function  Academic Article
• Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells  Academic Article
• Matched work high-intensity interval and continuous running induce similar increases in PGC-1α mRNA, AMPK, p38, and p53 phosphorylation in human skeletal muscle  Academic Article
• Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants  Academic Article
• Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK  Academic Article
• Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity  Academic Article
• MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis  Academic Article
• Molecular responses to high-intensity interval exerciseThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.  Academic Article
• Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: Identification of mitochondrial fission factor as a new AMPK substrate  Academic Article
• Muscle‐specific AMPK β1β2‐null mice display a myopathy due to loss of capillary density in nonpostural muscles  Academic Article
• Nuclear SIRT1 activity, but not protein content, regulates mitochondrial biogenesis in rat and human skeletal muscle  Academic Article
• PIKfyve: a new fish in the growing pool of AMPK substrates  Academic Article
• Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARα and UCP2 expression in rats  Academic Article
• Protein arginine methyltransferase expression, localization, and activity during disuse-induced skeletal muscle plasticity  Academic Article
• Proteome Analysis of Erythrocytes Lacking AMP-Activated Protein Kinase Reveals a Role of PAK2 Kinase in Eryptosis  Academic Article
• Rac1 and AMPK Account for the Majority of Muscle Glucose Uptake Stimulated by Ex Vivo Contraction but Not In Vivo Exercise  Academic Article
• Reduced glycogen availability is associated with increased AMPKα2 activity, nuclear AMPKα2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle  Academic Article
• Reduced skeletal muscle AMPK and mitochondrial markers do not promote age-induced insulin resistance  Academic Article
• Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue  Academic Article
• Regulation of glucose transporter 4 traffic by energy deprivation from mitochondrial compromise  Academic Article
• Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways  Academic Article
• Resveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis  Academic Article
• Role of the AMP-activated protein kinase in regulating fatty acid metabolism during exerciseThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.  Academic Article
• SIRT1 Takes a Backseat to AMPK in the Regulation of Insulin Sensitivity by Resveratrol  Academic Article
• Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis  Academic Article
• Salicylate improves macrophage cholesterol homeostasis via activation of Ampk  Academic Article
• Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1  Academic Article
• Salsalate, but not metformin or canagliflozin, slows kidney cyst growth in an adult-onset mouse model of polycystic kidney disease  Academic Article
• Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells  Academic Article
• Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin  Academic Article
• Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling  Academic Article
• Specific attenuation of protein kinase phosphorylation in muscle with a high mitochondrial content  Academic Article
• The AMP-Activated Protein Kinase: Role in Regulation of Skeletal Muscle Metabolism and Insulin Sensitivity  Academic Article
• The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase  Academic Article
• The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels  Academic Article
• The Role of AMPK in Neuromuscular Biology and Disease  Academic Article
• The Stimulatory Effect of Globular Adiponectin on Insulin-Stimulated Glucose Uptake and Fatty Acid Oxidation Is Impaired in Skeletal Muscle From Obese Subjects  Academic Article
• The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs  Academic Article
• The role of AMP‐activated protein kinase in the expression of the dystrophin‐associated protein complex in skeletal muscle  Academic Article
• The therapeutic potential of skeletal muscle plasticity in Duchenne muscular dystrophy: phenotypic modifiers as pharmacologic targets  Academic Article
• Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes  Academic Article
• Transcriptome and translational signaling following endurance exercise in trained skeletal muscle: impact of dietary protein  Academic Article
• Treatment of nonalcoholic fatty liver disease: role of AMPK  Academic Article
• Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo  Academic Article
• Utrophin A is essential in mediating the functional adaptations of mdx mouse muscle following chronic AMPK activation  Academic Article
• Whole Body Deletion of AMP-activated Protein Kinase β2 Reduces Muscle AMPK Activity and Exercise Capacity  Academic Article
• β‐adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling  Academic Article