Journal article
AMPK regulates the maintenance and remodelling of the neuromuscular junction
Abstract
OBJECTIVE: The molecular mechanisms underlying the maintenance and adaptability of the neuromuscular junction (NMJ) remain poorly understood. This study aimed to investigate the role of AMP-activated protein kinase (AMPK) as a key regulator of NMJ stability and plasticity.
METHOD: A comprehensive, multifaceted approach was employed, integrating genetic, physiological, and pharmacological methodologies to elucidate the role of skeletal muscle …
Authors
Ng SY; Mikhail AI; Mattina SR; Mohammed SA; Khan SK; Desjardins EM; Lim C; Phillips SM; Steinberg GR; Ljubicic V
Journal
Molecular Metabolism, Vol. 91, ,
Publisher
Elsevier
Publication Date
January 2025
DOI
10.1016/j.molmet.2024.102066
ISSN
2212-8778