Journal article
AXIN-AMPK signaling: Implications for healthy aging
Abstract
The energy sensor AMP kinase (AMPK) and the master scaffolding protein, AXIN, are two major regulators of biological processes in metazoans. AXIN-dependent regulation of AMPK activation plays a crucial role in maintaining metabolic homeostasis during glucose-deprived and energy-stressed conditions. The two proteins are also required for muscle function. While studies have refined our knowledge of various cellular events that promote the …
Authors
Mallick A; Gupta BP
Journal
F1000Research, Vol. 10, ,
Publisher
F1000Research
DOI
10.12688/f1000research.74220.1
ISSN
2051-7599