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The role of AMP‐activated protein kinase in the...
Journal article

The role of AMP‐activated protein kinase in the expression of the dystrophin‐associated protein complex in skeletal muscle

Abstract

Stimulation of AMPK induces the expression of dystrophin-associated protein complex (DAPC) components in skeletal muscle, whereas reductions in AMPK are associated with DAPC dysfunction. We sought to determine whether AMPK was necessary for the maintenance of DAPC expression in skeletal muscle. Fast, glycolytic extensor digitorum longus (EDL) and slow, oxidative soleus (Sol) muscles from wild-type mice and from littermates with skeletal …

Authors

Dial AG; Rooprai P; Lally JS; Bujak AL; Steinberg GR; Ljubicic V

Journal

The FASEB Journal, Vol. 32, No. 6, pp. 2950–2965

Publisher

Wiley

Publication Date

June 2018

DOI

10.1096/fj.201700868rrr

ISSN

0892-6638