von Willebrand Factor Concept

subject area of

• A Canadian phase II study evaluating the efficacy of rituximab in the management of patients with relapsed/refractory thrombotic thrombocytopenic purpura  Conferences
• A comparison of the quantitative ristocetin von willebrand factor assay by using fresh and fixed platelets  Journal Articles
• A multiprong approach to cancer gene therapy by coencapsulated cells  Journal Articles
• A phase III study comparing secondary long-term prophylaxis versus on-demand treatment with vWF/FVIII concentrates in severe inherited von Willebrand disease.  Journal Articles
• A von Willebrand factor fragment containing the D′D3 domains is sufficient to stabilize coagulation factor VIII in mice  Journal Articles
• Abnormal megakaryocyte development and platelet function in Nbeal2−/− mice  Journal Articles
• Acute Thrombocytopenia and Thrombosis  Journal Articles
• An autosomal dominant, qualitative platelet disorder associated with multimerin deficiency, abnormalities in platelet factor V, thrombospondin, von Willebrand factor, and fibrinogen and an epinephrine aggregation defect  Journal Articles
• Anemia-Induced Bleeding in Patients with Platelet Disorders  Journal Articles
• Antiangiogenic Cancer Therapy with Microencapsulated Cells  Journal Articles
• Aortic endothelial cell von Willebrand factor content, and circulating plasminogen activator inhibitor-1 are increased, but expression of endothelial leukocyte adhesion molecules is unchanged in insulin-dependent diabetic BB rats  Journal Articles
• Aortic stenosis and bleeding gastrointestinal angiodysplasia: is acquired von Willebrand's disease the link?  Journal Articles
• Biomarkers in acute respiratory distress syndrome  Journal Articles
• Biomarkers of Host Response Predict Primary End-Point Radiological Pneumonia in Tanzanian Children with Clinical Pneumonia: A Prospective Cohort Study  Journal Articles
• Calpain proteolysis of von Willebrand factor enhances its binding to platelet membrane glycoprotein IIb/IIIa: an explanation for platelet aggregation in thrombotic thrombocytopenic purpura  Journal Articles
• Carrier detection of haemophilia A using DNA markers in families with an isolated affected male  Journal Articles
• Changes in the aortic endothelium and plasma von Willebrand factor levels during the onset and progression of insulin-dependent diabetes in BB rats  Journal Articles
• Characterization of ADAMTS13 and von Willebrand factor levels in septic and non-septic ICU patients  Journal Articles
• Clopidogrel does not suppress blood markers of coagulation activation in aspirin-treated patients with non-ST-elevation acute coronary syndromes  Journal Articles
• Combined Immunotherapy and Antiangiogenic Therapy of Cancer with Microencapsulated Cells  Journal Articles
• Comparative pharmacokinetics of two extended half‐life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference?  Journal Articles
• Decreased von Willebrand factor protease activity associated with thrombocytopenic disorders  Journal Articles
• Detection of a Platelet-Agglutinating Factor in Thrombotic Thrombocytopenic Purpura  Journal Articles
• Efficacy and Safety of the Factor VIII/von Willebrand Factor Concentrate, Haemate-P/Humate-P: Ristocetin Cofactor Unit Dosing in Patients with von Willebrand Disease  Journal Articles
• Efficacy and safety evaluation of Fanhdi^®, a plasma‐derived factor VIII/ von Willebrand factor concentrate, in Von Willebrand's disease patients undergoing surgery or invasive procedures: A prospective clinical study  Journal Articles
• Efficacy of parenteral formulations of desmopressin in the treatment of bleeding disorders: A systematic review  Journal Articles
• Endothelial and Platelet Activation in Acute Ischemic Stroke and Its Etiological Subtypes  Journal Articles
• Evaluation of an automated method for measuring von Willebrand factor activity in clinical samples without ristocetin  Journal Articles
• Experimental angiogenesis of arterial vasa vasorum  Journal Articles
• Extending the pre-processing holding time of whole blood beyond 48 h reduces coagulation FVIII activity and immunoglobulin G content of recovered plasma  Journal Articles
• Fibrinolytic response to venous occlusion is decreased in patients after Kawasaki disease  Journal Articles
• First prospective report on immune tolerance in poor risk haemophilia A inhibitor patients with a single factor VIII/von Willebrand factor concentrate in an observational immune tolerance induction study  Journal Articles
• Gastrointestinal Angiodysplasia and Aortic Stenosis  Journal Articles
• Gastrointestinal bleeding, angiodysplasia, cardiovascular disease, and acquired von Willebrand syndrome  Journal Articles
• Gynecologic and obstetric management of women with von Willebrand disease: summary of 3 systematic reviews of the literature  Journal Articles
• HIT: still stringing us along  Journal Articles
• Helicobacter pylori infection is related to atheroma in patients undergoing coronary angiography  Journal Articles
• Hemostasis and atherosclerosis.  Journal Articles
• Hemostatic management of von Willebrand disease during childbirth with a plasma-derived von Willebrand factor/factor VIII concentrate  Journal Articles
• High prevalence of abnormal preoperative coagulation tests in patients with adolescent idiopathic scoliosis  Journal Articles
• Identification and characterization of a novel peptide from rainbow trout (Oncorhynchus mykiss) with antimicrobial activity against Streptococcus iniae  Journal Articles
• Immunodepletion of human plasma factor VIII  Journal Articles
• Immunolocalization of CD34 in Nasal Polyposis  Journal Articles
• Impaired endothelial antithrombotic activity following short-term interruption of continuous subcutaneous insulin infusion in type1 diabetic patients  Journal Articles
• Increases in factor VIII complex and fibrinolytic activity are dependent on exercise intensity  Journal Articles
• Influence of Tertiary paleoenvironmental changes on the diversification of South American mammals: a relaxed molecular clock study within xenarthrans.  Journal Articles
• Kinetic Modeling for BT200 to Predict the Level of Plasma-Derived Coagulation Factor VIII in Humans  Journal Articles
• Laboratory abnormalities in thrombotic thrombocytopenic purpura  Journal Articles
• Laboratory abnormalities in thrombotic thrombocytopenic purpura. Canadian Apheresis Group.  Journal Articles
• Laboratory assays of VWF activity and use of desmopressin trials in the diagnosis of VWD: a systematic review and meta-analysis  Journal Articles
• Local Molecular Clocks in Three Nuclear Genes: Divergence Times for Rodents and Other Mammals and Incompatibility Among Fossil Calibrations  Conferences
• Lung Homing of Endothelial Progenitor Cells in Humans with Asthma after Allergen Challenge  Journal Articles
• Management of Inheritedvon Willebrand Disease in Italy: Results from the Retrospective Study on 1234 Patients  Journal Articles
• Management of bleeding disorders: basic science  Journal Articles
• Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13  Journal Articles
• Mechanisms of ADAMTS13 regulation  Journal Articles
• Metalloprotease domain latency protects ADAMTS13 against broad-spectrum inhibitors of metalloproteases while maintaining activity toward VWF  Journal Articles
• Modification of von Willebrand Disease after Liver Transplantation  Journal Articles
• Molecular Phylogeny of Living Xenarthrans and the Impact of Character and Taxon Sampling on the Placental Tree Rooting  Journal Articles
• Molecular phylogenetics unveils the ancient evolutionary origins of the enigmatic fairy armadillos  Journal Articles
• Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion  Journal Articles
• Multimerin: a series of large disulfide-linked multimeric proteins within platelets  Journal Articles
• Occurrence of inhibitors in previously untreated or minimally treated patients with haemophilia A after exposure to a plasma‐derived solvent‐detergent factor VIII concentrate  Journal Articles
• Optimization of plasma-based BioID identifies plasminogen as a ligand of ADAMTS13  Journal Articles
• Outcomes of long‐term von Willebrand factor prophylaxis use in von Willebrand disease: A systematic literature review  Journal Articles
• Placenta Percreta Presents with Neoangiogenesis of Arteries with Von Willebrand Factor-Negative Endothelium  Journal Articles
• Plasma fibronectin depletion enhances platelet aggregation and thrombus formation in mice lacking fibrinogen and von Willebrand factor  Journal Articles
• Plasma-derived biological medicines used to promote haemostasis  Journal Articles
• Platelet activation and hypercoagulability following treatment with porcine factor VIII (HYATE:C)  Journal Articles
• Platelet activation induced by porcine factor VIII (HYATE:C)  Journal Articles
• Platelet adhesion to multimerin 1 in vitro: influences of platelet membrane receptors, von Willebrand factor and shear  Journal Articles
• Platelet factor 4 inhibits ADAMTS13 activity and regulates the multimeric distribution of von Willebrand factor  Journal Articles
• Probing ADAMTS13 Substrate Specificity using Phage Display  Journal Articles
• Prophylactic efficacy and pharmacokinetically guided dosing of a von Willebrand factor/factor VIII concentrate in adults and children with von Willebrand's disease undergoing elective surgery: a pooled and comparative analysis of data from USA and European Union clinical trials.  Journal Articles
• REVIEWING THE DYSREGULATION OF ADAMTS13 AND VWF IN SEPSIS  Journal Articles
• Relationship between platelet aggregating factor and von Willebrand factor in thrombotic thrombocytopenic purpura  Journal Articles
• Relationships between factor VIII:Ag and factor VIII in recombinant and plasma‐derived factor VIII concentrates  Journal Articles
• Reported prevalence of von Willebrand disease worldwide in relation to income classification  Journal Articles
• Response to “The 2021 von Willebrand disease guidelines: Clarity and controversy”  Journal Articles
• Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients  Conferences
• Safety and Efficacy of Continuous Infusion of a Combined Factor VIII – von Willebrand Factor (vWF) Concentrate (Haemate-P™) in Patients with von Willebrand Disease  Journal Articles
• Stability of relevant plasma protein activities in cryosupernatant plasma units during refrigerated storage for up to 5 days postthaw  Journal Articles
• Studies investigating platelet aggregation and release initiated by sera from patients with thrombotic thrombocytopenic purpura  Journal Articles
• Studies of multimerin in patients with von Willebrand disease and platelet von Willebrand factor deficiency  Journal Articles
• Studies of α-granule proteins in cultured human megakaryocytes  Journal Articles
• Surgical management of patients with von Willebrand disease: summary of 2 systematic reviews of the literature  Journal Articles
• TTP/HUS: observational studies generate hypotheses that lead to randomized controlled trials  Conferences
• Targeted ADAMTS-13 replacement therapy for thrombotic thrombocytopenic purpura  Journal Articles
• Technological advances in diagnostic testing for von Willebrand disease: new approaches and challenges  Journal Articles
• The APTT Response of Pregnant Plasma to Unfractionated Heparin  Journal Articles
• The Cleaved Peptide of PAR1 Results in a Redistribution of the Platelet Surface GPIb-IX-V Complex to the Surface-Connected Canalicular System  Journal Articles
• The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelet Physiology  Journal Articles
• The Influence of Helicobacter pylori Status on Circulating Levels of the Coagulation Factors Fibrinogen, von Willebrand Factor, Factor VII, and Factor VIII  Journal Articles
• The Systemic Effects of Intermittent Claudication are Reversed by Angioplasty  Journal Articles
• The association between tumour progression and vascularity in the oral mucosa  Journal Articles
• The effect of basal insulin glargine on the fibrinolytic system and von Willebrand factor in people with dysglycaemia and high risk for cardiovascular events: Swedish substudy of the Outcome Reduction with an Initial Glargine Intervention trial  Journal Articles
• The fraction of recombinant factor VIII:Ag unable to bind von Willebrand factor has no FVIII coagulant activity: studies in vitro  Journal Articles
• The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding  Journal Articles
• The von Willebrand factor–binding aptamer rondaptivon pegol as a treatment for severe and nonsevere hemophilia A  Journal Articles
• Thrombotic thrombocytopenic purpura  Journal Articles
• Thrombotic thrombocytopenic purpura: outcome in 24 patients with renal impairment treated with plasma exchange  Journal Articles
• Treatment and prevention of acute bleedings in von Willebrand disease – efficacy and safety of Wilate^®, a new generation von Willebrand factor/factor VIII concentrate  Journal Articles
• Understanding FVIII/VWF complex – report from a symposium of XXIX WFH meeting 2010  Journal Articles
• Undetected factor VIII in a patient with type 3 von Willebrands disease mistaken as severe haemophilia A  Journal Articles
• Unraveling von Willebrand factor deficiency  Journal Articles
• Visualization of an N-terminal fragment of von Willebrand factor in complex with factor VIII  Journal Articles
• Von Willebrand Disease: Gaining a global perspective  Journal Articles
• Von Willebrand factor and thrombin activation in children with newly diagnosed acute lymphoblastic leukemia: An impact of peripheral blasts  Journal Articles
• von Willebrand Factor: Form for Function  Journal Articles
• von Willebrand disease: proposing definitions for future research.  Journal Articles
• von Willebrand factor antigen--a possible biomarker of disease activity in childhood central nervous system vasculitis?  Journal Articles
• von Willebrand factor levels in the diagnosis of von Willebrand disease: a systematic review and meta-analysis  Journal Articles
• von Willebrand factor propeptide variants lead to impaired storage and ER retention in patient‐derived endothelial colony‐forming cells  Journal Articles