Visualization of an N-terminal fragment of von Willebrand factor in complex with factor VIII Academic Article uri icon

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abstract

  • Key Points The VWF D′ domains are flexibly tethered entities projecting outside antiparallel dimers of the VWF D3 domain. Extensive interactions between the VWF D′ domain and primarily the FVIII C1 domain mediate VWF-FVIII association.

authors

  • Yee, Andrew
  • Oleskie, Austin N
  • Dosey, Anne M
  • Kretz, Colin
  • Gildersleeve, Robert D
  • Dutta, Somnath
  • Su, Min
  • Ginsburg, David
  • Skiniotis, Georgios

publication date

  • August 20, 2015

published in