Immunodepletion of human plasma factor VIII Journal Articles

abstract

• Affinity chromatography of human cryosupernatants on anti-human factor VIII-Sepharose yielded a plasma devoid of detectable factor VIIIC, VIIIR:Ag, and VIIIR:WF activities. This plasma was indistinguishable from severe congenital hemophilic plasma when used as substrate in factor VIII coagulant assays.

authors

• Ofosu, Frederick A
• Cassidy, K
• Blajchman, Morris
• Hirsh, Jack

status

• published 

publication date

• October 1, 1980

has subject area

• 1102 Cardiorespiratory Medicine and Haematology (FoR)
• 1103 Clinical Sciences (FoR)
• 1114 Paediatrics and Reproductive Medicine (FoR)
• Absorption (MeSH)
• Animals (MeSH)
• Antibodies (MeSH)
• Blood Coagulation Tests (MeSH)
• Chromatography, Affinity (MeSH)
• Chromatography, Gel (MeSH)
• Factor VIII (MeSH)
• Hemophilia A (MeSH)
• Humans (MeSH)
• Immunology (Science Metrix)
• Immunosorbent Techniques (MeSH)
• Rabbits (MeSH)
• von Willebrand Factor (MeSH)

published in

• Blood  Journal

keywords

• Absorption
• Animals
• Antibodies
• Blood Coagulation Tests
• Chromatography, Affinity
• Chromatography, Gel
• Factor VIII
• Hemophilia A
• Humans
• Immunosorbent Techniques
• Rabbits
• von Willebrand Factor

Digital Object Identifier (DOI)

• 10.1182/blood.v56.4.604.bloodjournal564604

PubMed ID

• 6774788

start page

• 604

end page

• 607

volume

• 56

issue

• 4