Scholarly Works

Immunodepletion of human plasma factor VIII.

Journal article

Immunodepletion of human plasma factor VIII.

Abstract

Affinity chromatography of human cryosupernatants on anti-human factor VIII-Sepharose yielded a plasma devoid of detectable factor VIIIC, VIIIR:Ag, and VIIIR:WF activities. This plasma was indistinguishable from severe congenital hemophilic plasma when used as substrate in factor VIII coagulant assays.

Authors

Ofosu F; Cassidy K; Blajchman MA; Hirsh J

Journal

Blood, Vol. 56, No. 4, pp. 604–607

Publisher

American Society of Hematology

Publication Date

October 1, 1980

DOI

10.1182/blood.v56.4.604.bloodjournal564604

ISSN

0006-4971

Associated Experts

Frederick A Ofosu

Professor Emeritus, Faculty of Health Sciences

Jack Hirsh

Professor Emeritus, Faculty of Health Sciences

Labels

Fields of Research (FoR)

3101 Biochemistry and cell biology 32 Biomedical and Clinical Sciences 31 Biological Sciences 3201 Cardiovascular medicine and haematology 3213 Paediatrics

Medical Subject Headings (MeSH)

Absorption Animals Antibodies Blood Coagulation Tests Chromatography, Affinity Chromatography, Gel Factor VIII Hemophilia A Humans Immunosorbent Techniques Rabbits von Willebrand Factor

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