Journal article
Studies of α-granule proteins in cultured human megakaryocytes
Abstract
alpha-Granule protein storage is important for producing platelets with normal haemostatic function. The low to undetectable levels of several megakaryocyte-synthesized alpha-granule proteins in normal plasma suggest megakaryocytes are important to sequester these proteins in vivo. alpha-Granule protein storage in vitro has been studied using other cell types, with differences observed in how some proteins are processed compared to platelets. …
Authors
Veljkovic DK; Cramer EM; Alimardani G; Fichelson S; Massé J-M; Hayward CPM
Journal
Thrombosis and Haemostasis, Vol. 90, No. 05, pp. 844–852
Publisher
Thieme
Publication Date
2003
DOI
10.1160/th03-02-0125
ISSN
0340-6245