Thromboplastin Concept

subject area of

• "Therapeutic range" for oral anticoagulant therapy.  Journal Articles
• 4D intravital imaging identifies platelets as the predominant cellular procoagulant surface in a mouse hemostasis model  Journal Articles
• A Comparison of Lyophilized Artificially Depleted Plasmas and Lyophilized Plasmas From Patients Receiving Warfarin in Correcting for Coagulometer Effects on International Normalized Ratios  Journal Articles
• A Control Switch for Prothrombinase  Journal Articles
• A Prospective Study of the Value of Monitoring Heparin Treatment with the Activated Partial Thromboplastin Time  Journal Articles
• A revisit of the two-form kinetic model of prothrombinase: A rebuttal  Journal Articles
• Accumulation of Tissue Factor into Developing Thrombi In Vivo Is Dependent upon Microparticle P-Selectin Glycoprotein Ligand 1 and Platelet P-Selectin  Journal Articles
• Activated Protein C Up-Regulates IL-10 and Inhibits Tissue Factor in Blood Monocytes  Journal Articles
• Activated protein C modulates inflammation, apoptosis and tissue factor procoagulant activity by regulating endoplasmic reticulum calcium depletion in blood monocytes  Journal Articles
• Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII  Journal Articles
• Activation of factor V during intrinsic and extrinsic coagulation. Inhibition by heparin, hirudin and d-Phe-Pro-Arg-Ch2Cl  Journal Articles
• Activation of the Novel Prothrombinase, fgl2, as a Basis for the Pregnancy Complications Spontaneous Abortion and Pre‐eclampsia  Journal Articles
• Alpha-1 proteinase inhibitor M358R reduces thrombin generation when displayed on the surface of cells expressing tissue factor  Journal Articles
• Analysis of Inhibition Rate Enhancement by Covalent Linkage of Antithrombin to Heparin as a Potential Predictor of Reaction Mechanism  Journal Articles
• Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor  Journal Articles
• Binding of Anti-GRP78 Autoantibodies to Cell Surface GRP78 Increases Tissue Factor Procoagulant Activity via the Release of Calcium from Endoplasmic Reticulum Stores  Journal Articles
• Breast cancer stem-like cells can promote metastasis by activating platelets and down-regulating antitumor activity of natural killer cells  Journal Articles
• Confusion Over the Therapeutic Range for Monitoring Oral Anticoagulant Therapy in North America  Journal Articles
• Contribution of Host-Derived Tissue Factor to Tumor Neovascularization  Journal Articles
• Covalently linking heparin to antithrombin enhances prothrombinase inhibition on activated platelets  Journal Articles
• Cutting Edge: Cytokine-Dependent Abortion in CBA × DBA/2 Mice Is Mediated by the Procoagulant fgl2 Prothombinase  Journal Articles
• Development of a continuous assay for the measurement of tissue factor procoagulant activity on intact cells  Journal Articles
• Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation  Journal Articles
• Dose-Response Study of Recombinant Factor VIIa/Tissue Factor Inhibitor Recombinant Nematode Anticoagulant Protein c2 in Prevention of Postoperative Venous Thromboembolism in Patients Undergoing Total Knee Replacement  Journal Articles
• Effect of a novel covalent antithrombin-heparin complex on thrombin generation on fetal distal lung epithelium  Journal Articles
• Effect of gaboon viper (Bitis gabonica) venom on blood coagulation, platelets, and the fibrinolytic enzyme system  Journal Articles
• Effects of Sulfated Polysaccharides on Inhibition of Thrombus Formation initiated by Different Stimuli  Journal Articles
• Elevated tissue factor procoagulant activity in CD133‐positive cancer cells  Journal Articles
• Enoxaparin, a low molecular weight heparin, inhibits platelet-dependent prothrombinase assembly and activity by factor-Xa neutralization.  Journal Articles
• Extracellular Histones Increase Tissue Factor Activity and Enhance Thrombin Generation by Human Blood Monocytes  Journal Articles
• Factor V Is Complexed with Multimerin in Resting Platelet Lysates and Colocalizes with Multimerin in Platelet α-Granules  Journal Articles
• Factor VII Deficiency Caused by a Structural Variant N57D of the First Epidermal Growth Factor Domain  Journal Articles
• Fgl2 prothrombinase expression in mouse trophoblast and decidua triggers abortion but may be countered by OX-2  Journal Articles
• Frequent association of factor VII defects with other clotting disorders  Journal Articles
• Further Evidence for Two Functional Forms of Prothrombinase Each Specific for Either of the Two Prothrombin Activation Cleavages  Journal Articles
• Getting a GRP on Tissue Factor Activation  Journal Articles
• HD1, a Thrombin-directed Aptamer, Binds Exosite 1 on Prothrombin with High Affinity and Inhibits Its Activation by Prothrombinase  Journal Articles
• HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions  Journal Articles
• Heparin Cofactor II and Other Endogenous Factors in the Mediation of the Antithrombotic and Anticoagulant Effects of Heparin and Dermatan Sulfate  Journal Articles
• Heparin and Low Molecular Weight Heparins Inhibit Prothrombinase Formation but not its Activity in Plasma  Journal Articles
• Hypersulfated Low Molecular Weight Heparin with Reduced Affinity for Antithrombin Acts as an Anticoagulant by Inhibiting Intrinsic Tenase and Prothrombinase  Journal Articles
• Identification of a Unique Glomerular Factor X Activator in Murine Lupus Nephritis  Journal Articles
• Identification of the MMRN1 Binding Region within the C2 Domain of Human Factor V  Journal Articles
• Impact of Chemotherapy on Thrombin Generation and on the Protein C Pathway in Breast Cancer Patients  Journal Articles
• Impaired endothelial antithrombotic activity following short-term interruption of continuous subcutaneous insulin infusion in type1 diabetic patients  Journal Articles
• Inadequate monitoring of warfarin dosage [letter] [see comments]  Journal Articles
• Incorporation of Factor Va into Prothrombinase Is Required for Coordinated Cleavage of Prothrombin by Factor Xa  Journal Articles
• Inferior Vena Cava Ligation Rapidly Induces Tissue Factor Expression and Venous Thrombosis in Rats  Journal Articles
• Influence of Mechanical Stretch on Thrombin Regulation by Fetal Mixed Lung Cells  Journal Articles
• Inhibition of platelet-dependent prothrombinase activity and thrombin generation by glycoprotein IIb/IIIa receptor-directed antagonists: potential contributing mechanism of benefit in acute coronary syndromes.  Journal Articles
• Is the dose of warfarin prescribed by American physicians unnecessarily high?  Journal Articles
• Kinetic Analysis of a Unique Direct Prothrombinase, fgl2, and Identification of a Serine Residue Critical for the Prothrombinase Activity  Journal Articles
• Laboratory monitoring of oral anticoagulant therapy.  Journal Articles
• Leukocyte-versus microparticle-mediated tissue factor transfer during arteriolar thrombus development  Journal Articles
• Low-Molecular-Weight Heparin as an Adjunct to Thrombolysis in ST Elevation Myocardial Infarction  Journal Articles
• Mechanism of Action and Monitoring of Anticoagulants  Journal Articles
• Mechanism of inhibition of the prothrombinase complex by a covalent antithrombin-heparin complex  Journal Articles
• Microangiopathic Haemolytic Anaemia (MHA)  Journal Articles
• Multicentric Evaluation of a New PT Reagent Based on Recombinant Human Tissue Factor and Synthetic Phospholipids  Journal Articles
• Multicentric evaluation of heparinase on aPTT, thrombin clotting time and a new PT reagent based on recombinant human tissue factor  Journal Articles
• New Anticoagulants  Journal Articles
• Oncogenes as Regulators of Tissue Factor Expression in Cancer: Implications for Tumor Angiogenesis and Anti-Cancer Therapy  Journal Articles
• Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis  Journal Articles
• Oral anticoagulant therapy. Urgent need for standardization.  Journal Articles
• Organ-specific bleeding patterns of anticoagulant therapy: lessons from clinical trials  Journal Articles
• Overexpression of the 78-kDa Glucose-regulated Protein/Immunoglobulin-binding Protein (GRP78/BiP) Inhibits Tissue Factor Procoagulant Activity  Journal Articles
• Plasma factor VII and thrombin–antithrombin III levels indicate increased tissue factor activity in sickle cell patients  Journal Articles
• Plasma fibrinopeptide A levels in symptomatic venous thromboembolism  Journal Articles
• Platelet factor 3 availability and the platelet release reaction  Other
• Platelet factor V New York: A defect in factor V distinct from that in factor V Quebec resulting in impaired prothrombinase generation  Journal Articles
• Probable regulation of factor VIIa–tissue factor and prothrombinase by factor Xa–TFPI and TFPI in vivo  Journal Articles
• Procoagulants in fetus rejection: the role of the OX-2 (CD200) tolerance signal  Journal Articles
• Prolonged Expression of Procoagulant Activity of Human Platelets Degranulated by Thrombin  Journal Articles
• Prolonged Prothrombin Time and Partial Thromboplastin Time in Disseminated Intravascular Coagulation not Due to Deficiency of Factors V and VIII  Journal Articles
• Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse  Journal Articles
• Reliability of the international normalized ratio for monitoring the induction phase of warfarin: Comparison with the prothrombin time ratio  Journal Articles
• Role of the tissue factor pathway in the biology of tumor initiating cells  Journal Articles
• Serum-induced platelet procoagulant activity: An assay for the characterization of prothrombotic disorders  Journal Articles
• Small Molecules Targeting GRP78 Mitigate Anti- GRP78 Autoantibody-Mediated Tissue Factor Procoagulant Activity in Cultured Endothelial Cells  Journal Articles
• Small Subcutaneous Doses of Heparin in Prevention of Venous Thrombosis  Journal Articles
• Substandard monitoring of warfarin in North America. Time for change  Journal Articles
• THE DEVELOPMENT OF UROKINASE AS A THROMBOLYTIC AGENT. MAINTENANCE OF A SUSTAINED THROMBOLYTIC STATE IN MAN BY ITS INTRAVENOUS INFUSION.  Journal Articles
• Th1 Cytokines and the Prothrombinase fgl2 in Stress‐triggered and Inflammatory Abortion  Journal Articles
• The Activated Partial Thromboplastin Time in the Control of Heparin Treatment  Journal Articles
• The Antithrombotic Properties of Human Prothrombin Fragment 1.2 in Mice  Journal Articles
• The Emerging Role of Immunoregulation of Fibrinogen‐Related Procoagulant Fgl2 in the Success or Spontaneous Abortion of Early Pregnancy in Mice and Humans  Journal Articles
• The M358R variant of α 1 -proteinase inhibitor inhibits coagulation factor VIIa  Journal Articles
• The Value of Plasma Calibrants in Correcting Coagulometer Effects on International Normalized Ratios:An International Multicenter Study  Journal Articles
• The activation of coagulation by extracts of mucus: a possible pathway of intravascular coagulation accompanying adenocarcinomas.  Journal Articles
• The anticoagulant action of puff adder (B. arietans) venom.  Journal Articles
• The direct binding of human factor VII in plasma to recombinant human tissue factor  Journal Articles
• The effects of chemotherapeutic agents on the regulation of thrombin on cell surfaces  Journal Articles
• The first epidermal growth factor domain of human coagulation factor VII is essential for binding with tissue factor  Journal Articles
• The inhibition of the anticoagulant activity of heparin by platelets, brain phospholipids, and tissue factor  Journal Articles
• The interaction of fragment 1 of prothrombin with the membrane surface is a prerequisite for optimum expression of factor Va cofactor activity within prothrombinase  Journal Articles
• The onerous task of comparing treatments in inhibitor patients  Journal Articles
• The optimal intensity of oral anticoagulant therapy  Journal Articles
• The role of leukocytes in thrombosis  Journal Articles
• The role of tumor-and host-related tissue factor pools in oncogene-driven tumor progression  Journal Articles
• The tissue factor pathway in ischemic stroke  Journal Articles
• The value of monitoring heparin therapy in the prevention of recurrence in patients with venous thromboembolic disease.  Journal Articles
• Thrombin and Antithrombotics  Journal Articles
• Thrombotic characteristics of extracellular vesicles derived from prostate cancer cells  Journal Articles
• Tissue Factor and Thrombosis Models  Journal Articles
• Tissue factor microparticles and haemophilia  Journal Articles
• Urokinase Therapy: Dosage Schedules and Coagulant Side Effects  Journal Articles
• Vascular Endothelial Tissue Factor Pathway Inhibitor Kinetics in Culture Following Exposure to DX-9065a—A Selective and Direct Factor Xa Inhibitor  Journal Articles
• Volutrauma activates the clotting cascade in the newborn but not adult rat  Journal Articles
• “Therapeutic Range” for Oral Anticoagulant Therapy  Journal Articles