Journal article
A Prospective Study of the Value of Monitoring Heparin Treatment with the Activated Partial Thromboplastin Time
Abstract
Two hundred and thirty-four patients treated with continuous intravenous infusions of heparin were studied prospectively to seek a relation between the activated partial thromboplastin time (APTT) and recurrent venous thromboembolism or bleeding during treatment. One hundred and sixty-two patients were treated for venous thromboembolism and the remaining 72 for other diseases. The heparin dose was adjusted to keep the APTT between 1 1/2 and 2 …
Authors
Basu D; Gallus A; Hirsh J; Cade J
Journal
The New England Journal of Medicine, Vol. 287, No. 7, pp. 324–327
Publisher
Massachusetts Medical Society
Publication Date
August 17, 1972
DOI
10.1056/nejm197208172870703
ISSN
0028-4793