Antithrombins Concept

subject area of

• 2014 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation  Academic Article
• d-Dimer Testing to Determine the Duration of Anticoagulation Therapy  Academic Article
• A novel and de novo spontaneous point mutation (Glu271STOP) of the antithrombin gene results in a type I deficiency and thrombophilia  Academic Article
• A novel antithrombin-heparin covalent complex  Academic Article
• A novel long‐acting synthetic factor Xa inhibitor (SanOrg34006) to replace warfarin for secondary prevention in deep vein thrombosis. A Phase II evaluation  Academic Article
• Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine—A Multicenter Trial  Academic Article
• Activated prothrombin complex concentrate for dabigatran-associated bleeding  Academic Article
• Activation of factor X and prothrombin in antithrombin-III depleted plasma: The effects of heparin  Academic Article
• Acute management of bleeding in patients on novel oral anticoagulants  Academic Article
• Adherence to anticoagulant treatment with dabigatran in a real‐world setting  Academic Article
• Advances in Antithrombotic Therapy: Novel Agents  Academic Article
• Advances in the management of venous thromboembolism.  Academic Article
• American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism  Academic Article
• Amino acid substitutions of the P2 residue of human antithrombin that either enhance or impair function  Academic Article
• An important role for the activation peptide domain in controlling factor IX levels in the blood of haemophilia B mice  Conference Paper
• An open-label study of the pharmacokinetics and pharmacodynamics of dabigatran etexilate 150 mg once daily in Caucasian patients with moderate renal impairment undergoing primary unilateral elective total knee or hip replacement surgery  Academic Article
• Analysis of Inhibition Rate Enhancement by Covalent Linkage of Antithrombin to Heparin as a Potential Predictor of Reaction Mechanism  Academic Article
• Analysis of Upper Gastrointestinal Adverse Events Among Patients Given Dabigatran in the RE-LY Trial  Academic Article
• Angiotensin-converting enzyme 2 (ACE2) levels in relation to risk factors for COVID-19 in two large cohorts of patients with atrial fibrillation  Academic Article
• Antiangiogenic Antithrombin Induces Global Changes in the Gene Expression Profile of Endothelial Cells  Academic Article
• Antiangiogenic antithrombin down-regulates the expression of the proangiogenic heparan sulfate proteoglycan, perlecan, in endothelial cells  Academic Article
• Anticoagulant mechanisms of covalent antithrombin-heparin investigated by thrombelastography  Academic Article
• Antithrombin alfa in hereditary antithrombin deficient patients: A phase 3 study of prophylactic intravenous administration in high risk situations  Academic Article
• Antithrombin-Heparin Covalent Complex  Academic Article
• Antithrombin-Independent Anticoagulation by Hypersulfated Low-Molecular-Weight Heparin  Academic Article
• Antithrombin-heparin covalent complex reduces microemboli during cardiopulmonary bypass in a pig model  Academic Article
• Antithrombins: Their Potential as Antithrombotic Agents  Academic Article
• Antithrombotic Agents  Academic Article
• Argatroban Anticoagulation in Patients With Heparin-Induced Thrombocytopenia  Academic Article
• Assessing the impact of dabigatran and warfarin on health-related quality of life: Results from an RE-LY sub-study  Academic Article
• Balancing the Benefits and Risks of 2 Doses of Dabigatran Compared With Warfarin in Atrial Fibrillation  Academic Article
• Basic coagulation tests as surrogates of dabigatran levels in a pre-operative setting: Analysis of five activated partial thromboplastin time reagents and thrombin time  Academic Article
• Beyond Heparin and Aspirin  Academic Article
• Biodistribution of covalent antithrombin-heparin complexes  Academic Article
• Biologic rationale for the therapeutic role of specific antithrombins  Academic Article
• Bivalent Binding to γA/γ′-Fibrin Engages Both Exosites of Thrombin and Protects It from Inhibition by the Antithrombin-Heparin Complex  Academic Article
• Bivalent direct thrombin inhibitors: hirudin and bivalirudin  Academic Article
• Bivalirudin in patients with heparin-induced thrombocytopenia undergoing percutaneous coronary intervention.  Academic Article
• Bivalirudin versus Unfractionated Heparin during Percutaneous Coronary Intervention in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome Initially Treated with Fondaparinux: Results from an International, Multicenter, Randomized Pilot Study (  Academic Article
• Bivalirudin, thrombin and platelets: clinical implications and future directions.  Academic Article
• Bivalirudin: a review  Academic Article
• Bleeding Complications in Patients with Acute Coronary Syndromes: Are They Important and How Can We Prevent Them?  Academic Article
• Bleeding events with dabigatran or warfarin in patients with venous thromboembolism  Academic Article
• Blood-compatible biomaterials by surface coating with a novel antithrombin–heparin covalent complex  Academic Article
• By Increasing the Affinity of Heparin for Fibrin, Zn²⁺ Promotes the Formation of a Ternary Heparin–Thrombin–Fibrin Complex That Protects Thrombin from Inhibition by Antithrombin  Academic Article
• Causes of Death and Influencing Factors in Patients With Atrial Fibrillation  Academic Article
• Characterization of a highly polymorphic trinucleotide short tandem repeat within the human antithrombin gene  Academic Article
• Chronic performance of polyurethane catheters covalently coated with ATH complex: A rabbit jugular vein model  Academic Article
• Clinical implications of reversal agents for direct oral anticoagulants  Academic Article
• Comparison of Characteristics and Outcomes of Dabigatran Versus Warfarin in Hypertensive Patients With Atrial Fibrillation (from the RE-LY Trial)  Academic Article
• Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the Randomized Evaluation of PCI Linking Angiomax to Reduced Clinical Events [REPLACE]-1 trial)  Academic Article
• Comparison of bleeding risk scores in patients with atrial fibrillation: insights from the RE-LY trial  Academic Article
• Comparison of dabigatran versus warfarin in diabetic patients with atrial fibrillation: Results from the RE-LY trial  Academic Article
• Comparison of recombinant and plasma-derived antithrombin biodistribution in a rabbit model  Academic Article
• Comparison of the effect of dabigatran and dalteparin on thrombus stability in a murine model of venous thromboembolism  Academic Article
• Cost-effectiveness analysis of dabigatran and anticoagulation monitoring strategies of vitamin K antagonist  Academic Article
• Covalent antithrombin-heparin effect on thrombin-thrombomodulin and activated protein C reaction with factor V/Va  Academic Article
• Covalent antithrombin–heparin complexes  Academic Article
• Covalently linking heparin to antithrombin enhances prothrombinase inhibition on activated platelets  Academic Article
• Current agents for the treatment of patients with heparin-induced thrombocytopenia  Academic Article
• Dabigatran Reversal With Idarucizumab in Patients Requiring Urgent Surgery  Academic Article
• Dabigatran Reversal With Idarucizumab in Patients With Renal Impairment  Academic Article
• Dabigatran Reversal with Idarucizumab  Academic Article
• Dabigatran Treatment of Acute Noncardioembolic Ischemic Stroke  Academic Article
• Dabigatran Versus Warfarin  Academic Article
• Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function  Academic Article
• Dabigatran attenuates thrombin generation to a lesser extent than warfarin: could this explain their differential effects on intracranial hemorrhage and myocardial infarction?  Academic Article
• Dabigatran following acute transient ischemic attack and minor stroke II (DATAS II)  Academic Article
• Dabigatran in clinical practice: Contemporary overview of the evidence  Academic Article
• Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial  Academic Article
• Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve‐Induced Thrombin Generation  Academic Article
• Dabigatran monitoring made simple?  Academic Article
• Dabigatran reversal by idarucizumab in the setting of intracranial hemorrhage: A systematic review of the literature  Academic Article
• Dabigatran versus Warfarin for Acute Venous Thromboembolism in Elderly or Impaired Renal Function Patients: Pooled Analysis of RE-COVER and RE-COVER II.  Academic Article
• Dabigatran vs. warfarin in relation to the presence of left ventricular hypertrophy in patients with atrial fibrillation— the Randomized Evaluation of Long-term anticoagulation therapY (RE-LY) study  Academic Article
• Dabigatran-Induced Acute Hepatitis  Academic Article
• Dabigatran-related coagulopathy: when can we assume the effect has “worn off”?  Academic Article
• Decreased concentration of antithrombin after preoperative therapeutic heparin does not cause heparin resistance during cardiopulmonary bypass  Academic Article
• Defining the heparin-binding domain of antithrombin  Academic Article
• Definition of clinically relevant non‐major bleeding in studies of anticoagulants in atrial fibrillation and venous thromboembolic disease in non‐surgical patients: communication from the SSC of the ISTH  Academic Article
• Delayed but not Early Treatment with DNase Reduces Organ Damage and Improves Outcome in a Murine Model of Sepsis  Academic Article
• Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatran  Academic Article
• Diagnosis and management of inherited and acquired thrombophilias.  Academic Article
• Differences between perspectives of physicians and patients on anticoagulation in patients with atrial fibrillation: observational study Commentary: Varied preferences reflect the reality of clinical practice  Academic Article
• Direct Oral Anticoagulant- or Warfarin-Related Major Bleeding  Academic Article
• Direct Oral Anticoagulants Versus Vitamin K Antagonists in Patients Undergoing Cardioversion for Atrial Fibrillation: a Systematic Review and Meta-analysis  Academic Article
• Direct Thrombin Inhibitors  Conference Paper
• Direct comparative effectiveness and safety between non-vitamin K antagonist oral anticoagulants for stroke prevention in nonvalvular atrial fibrillation: a systematic review and meta-analysis of observational studies  Academic Article
• Direct thrombin inhibitors for treatment of arterial thrombosis: potential differences between bivalirudin and hirudin  Conference Paper
• Direct thrombin inhibitors in acute coronary syndromes: effect in patients undergoing early percutaneous coronary intervention  Academic Article
• Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data  Academic Article
• Direct thrombin inhibitors in cardiovascular disease  Academic Article
• Discordance between the anti-Xa activity and the antithrombotic activity of an ultra-low molecular weight heparin fraction  Academic Article
• Discrepancy between antithrombin activity methods revealed in Antithrombin Stockholm: do factor Xa–based methods overestimate antithrombin activity in some patients?  Academic Article
• Do sick newborn infants benefit from participation in a randomized clinical trial?  Academic Article
• Effect of Covalent Serpin–Heparinoid Complexes on Plasma Thrombin Generation on Fetal Distal Lung Epithelium  Academic Article
• Effect of covalent antithrombin-heparin complex on developmental mechanisms in the lung  Academic Article
• Effect of covalent antithrombin-heparin on activated protein C inactivation by protein C inhibitor  Academic Article
• Effect of substrate and fibrin polymerization inhibitor on determination of plasma thrombin generation in vitro  Academic Article
• Effects of dabigatran according to age in atrial fibrillation  Academic Article
• Efficacy of dabigatran versus warfarin in patients with acute venous thromboembolism in the presence of thrombophilia: Findings from RE-COVER^®, RE-COVER™ II, and RE-MEDY™  Academic Article
• Emergency care of patients receiving non-vitamin K antagonist oral anticoagulants  Academic Article
• Enhanced TRAP-induced platelet aggregation with dabigatran — Clinical perspective  Academic Article
• Establishing Therapeutic Equivalence of Complex Pharmaceuticals: The Case of Dabigatran  Academic Article
• Evaluation of Potential Early Markers of Chorioamnionitis Associated with Preterm Premature Ruptured Membranes  Academic Article
• Exosites 1 and 2 Are Essential for Protection of Fibrin-bound Thrombin from Heparin-catalyzed Inhibition by Antithrombin and Heparin Cofactor II  Academic Article
• Factor Xa or thrombin: Is thrombin a better target?  Conference Paper
• Genetic linkage studies in antithrombin-deficient kindreds using a highly polymorphic trinucleotide short tandem repeat (str) within the human antithrombin gene  Academic Article
• HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions  Academic Article
• HS3ST1 genotype regulates antithrombin's inflammomodulatory tone and associates with atherosclerosis  Academic Article
• Hemodialysis for the treatment of dabigatran‐associated bleeding: a case report and systematic review  Academic Article
• Hemorrhagic complications in association with percutaneous coronary intervention: can the risk be attenuated?  Academic Article
• Heparin and low molecular weight heparins as scaffolds for assembling antithrombin and serine proteases  Academic Article
• Heparin-induced thrombocytopenia and its treatment.  Conference Paper
• Hirudin and thrombosis prophylaxis  Academic Article
• How I Diagnose and Manage HIT  Academic Article
• How I treat target-specific oral anticoagulant–associated bleeding  Academic Article
• How to use unfractionated heparin to treat neonatal thrombosis in clinical practice  Academic Article
• Hypercoagulability.  Academic Article
• Hypercoagulable States  Academic Article
• Hypersulfated Low Molecular Weight Heparin with Reduced Affinity for Antithrombin Acts as an Anticoagulant by Inhibiting Intrinsic Tenase and Prothrombinase  Academic Article
• Idarucizumab  Academic Article
• Idarucizumab for dabigatran overdose  Academic Article
• Immobilization of an antithrombin–heparin complex on gold: Anticoagulant properties and platelet interactions  Academic Article
• Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex  Academic Article
• In vivo rabbit acute model tests of polyurethane catheters coated with a novel antithrombin-heparin covalent complex  Academic Article
• In-vitro assessment of the effect of dabigatran on thrombosis of adult and neonatal plasma  Academic Article
• Incidence of Direct Oral Anticoagulant Prescriptions in Kidney Transplant Recipients in Ontario, Canada  Academic Article
• Individual Treatment Effect Estimation of 2 Doses of Dabigatran on Stroke and Major Bleeding in Atrial Fibrillation  Academic Article
• Inhibition of Fibrin-Bound Thrombin by a Covalent Antithrombin-Heparin Complex  Academic Article
• Inhibition of plasmin generation in plasma by heparin, low molecular weight heparin, and a covalent antithrombin–heparin complex  Academic Article
• Inhibition of the prothrombinase complex on red blood cells by heparin and covalent antithrombin-heparin complex  Academic Article
• Insights into the role of thrombin in the pathogenesis of recurrent ischaemia after acute coronary syndrome  Academic Article
• Interactions of antithrombin and proteins in the plasma contact activation system with immobilized functional heparin  Academic Article
• Interactions of heparin and a covalently-linked antithrombin-heparin complex with components of the fibrinolytic system  Academic Article
• Intracellular events determine the fate of antithrombin Utah  Academic Article
• Intravascular Targeting of a New Anticoagulant Heparin Compound  Academic Article
• Investigation of the Anticoagulant Mechanisms of a Covalent Antithrombin-Heparin Complex  Academic Article
• Is there really misuse and abuse of dabigatran?  Academic Article
• Isoform composition of antithrombin in a covalent antithrombin–heparin complex  Academic Article
• Key references: Protein C, protein S, and antithrombin deficiencies.  Academic Article
• Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants  Academic Article
• Laboratory Measurement of the Anticoagulant Activity of the Non–Vitamin K Oral Anticoagulants  Academic Article
• Laboratory Monitoring of Non–Vitamin K Antagonist Oral Anticoagulant Use in Patients With Atrial Fibrillation  Academic Article
• Letter by Van de Werf et al Regarding Article, “Using Dabigatran in Patients With Stroke: A Practical Guide for Clinicians”  Academic Article
• Life-Threatening Thrombosis in Mice With Targeted Arg48-to-Cys Mutation of the Heparin-Binding Domain of Antithrombin  Academic Article
• Locations and Mucosal Lesions Responsible for Major Gastrointestinal Bleeding in Patients on Warfarin or Dabigatran  Academic Article
• Long-Term Oral Anticoagulant Therapy in Patients With Unstable Angina or Suspected Non–Q-Wave Myocardial Infarction  Academic Article
• Long-term evaluation of dabigatran 150 vs. 110 mg twice a day in patients with non-valvular atrial fibrillation  Academic Article
• Management and Outcomes of Major Bleeding During Treatment With Dabigatran or Warfarin  Academic Article
• Management of Anticoagulation Around Pacemaker and Defibrillator Surgery  Academic Article
• Management of Patients with Acute Coronary Syndromes  Academic Article
• Management of Patients with Hereditary Hypercoagulable Disorders  Academic Article
• Management of heparin-induced thrombocytopenia: a critical comparison of lepirudin and argatroban  Academic Article
• Measurement of Dabigatran Drug Levels to Manage Patients Taking Interacting Drugs: A Case Report  Academic Article
• Measuring Dabigatran Levels: What Tests Are Available and What Still Needs to Be Done?  Academic Article
• Mechanism of Catalysis of Inhibition of Factor IXa by Antithrombin in the Presence of Heparin or Pentasaccharide  Academic Article
• Mechanism of inhibition of the prothrombinase complex by a covalent antithrombin-heparin complex  Academic Article
• Mechanisms for the Anticoagulant Effects of Synthetic Antithrombins  Academic Article
• Meta-Analysis Comparing Bivalirudin Versus Heparin Monotherapy on Ischemic and Bleeding Outcomes After Percutaneous Coronary Intervention  Academic Article
• Meta-Analysis of Effects of Bivalirudin Versus Heparin on Myocardial Ischemic and Bleeding Outcomes After Percutaneous Coronary Intervention  Academic Article
• Mixing study to diagnose heparin‐resistance caused by functional antithrombin deficiency  Academic Article
• Modification of Polyurethane Surface with an Antithrombin–Heparin Complex for Blood Contact: Influence of Molecular Weight of Polyethylene Oxide Used as a Linker/Spacer  Academic Article
• Molecular basis of inherited human antithrombin deficiency  Academic Article
• Mortality outcomes in patients receiving direct oral anticoagulants: a systematic review and meta‐analysis of randomized controlled trials  Academic Article
• Mutation of Any Site of N-Linked Glycosylation Accelerates the In Vivo Clearance of Recombinant Rabbit Antithrombin  Academic Article
• Myocardial Ischemic Events in Patients With Atrial Fibrillation Treated With Dabigatran or Warfarin in the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) Trial  Academic Article
• NOAC monitoring, reversal agents, and post-approval safety and effectiveness evaluation: A cardiac safety research consortium think tank  Academic Article
• New anticoagulants.  Academic Article
• Nonheparin Anticoagulants for Heparin-Induced Thrombocytopenia  Academic Article
• Novel oral anticoagulants in gastroenterology practice  Academic Article
• Only high levels of dabigatran attenuate catheter thrombosis in vitro and in rabbits  Academic Article
• Oral Anticoagulant Therapy  Academic Article
• Overview of the New Oral Anticoagulants  Academic Article
• Parenteral Anticoagulants  Academic Article
• Perioperative Management of Dabigatran  Academic Article
• Perioperative management of patients who are receiving a novel oral anticoagulant  Academic Article
• Periprocedural Management and Approach to Bleeding in Patients Taking Dabigatran  Academic Article
• Persistence With Dabigatran Therapy at 2 Years in Patients With Atrial Fibrillation  Academic Article
• Plasminogen II accumulates five times faster than plasminogen I at the site of a balloon de-endothelializing injury in vivo to the rabbit aorta: Comparison with other hemostatic proteins  Academic Article
• Polyphosphate binds with high affinity to exosite II of thrombin  Academic Article
• Polyurethane modified with an antithrombin-heparin complex via polyethylene oxide linker/spacers: Influence of PEO molecular weight and PEO-ATH bond on catalytic and direct anticoagulant functions  Academic Article
• Potent Antithrombin Activity and Delayed Clearance From the Circulation Characterize Recombinant Hirudin Genetically Fused to Albumin  Academic Article
• Practical management of bleeding in patients receiving non-vitamin K antagonist oral anticoagulants  Academic Article
• Preference-Based Antithrombotic Therapy in Atrial Fibrillation: Implications for Clinical Decision Making  Academic Article
• Preparation and partial characterization of human plasma depleted of antithrombin-III by heparin-sepharose affinity chromatography  Academic Article
• Prevalence of antithrombin deficiency in healthy blood donors: A cross-sectional study  Academic Article
• Preventing Cardioembolic Stroke in Atrial Fibrillation with Dabigatran  Academic Article
• Prevention and treatment of thrombosis: novel strategies arising from our understanding the healthy endothelium.  Academic Article
• Proceedings: Platelet survival, fibrinolytic activity, antithrombin II (AT III) level and fibrinogen survival in venous thromboembolism (VTE).  Academic Article
• Progressive, Fatal Thrombosis Associated With Heparin-Induced Thrombocytopenia After Cardiac Surgery Despite “Therapeutic” Anticoagulation With Argatroban: Potential Role for PTT and ACT Confounding  Academic Article
• Protein adsorption on polyurethane catheters modified with a novel antithrombin-heparin covalent complex  Academic Article
• RE-COVERY DVT/PE: Rationale and design of a prospective observational study of acute venous thromboembolism with a focus on dabigatran etexilate  Academic Article
• Randomized comparison of direct thrombin inhibition versus heparin in conjunction with fibrinolytic therapy for acute myocardial infarction: results from the GUSTO-IIb Trial. Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes (GUSTO-IIb) Investigators.  Academic Article
• Reactivation of coagulation after stopping infusions of recombinant hirudin and unfractionated heparin in unstable angina and myocardial infarction without ST elevation: results of a randomized trial  Academic Article
• Reactivation of ischemic events in acute coronary syndromes: results from GUSTO-IIb. Gobal Use of Strategies To Open occluded arteries in acute coronary syndromes.  Academic Article
• Real-world variability in dabigatran levels in patients with atrial fibrillation: reply  Academic Article
• Real‐world variability in dabigatran levels in patients with atrial fibrillation  Academic Article
• Reasons for hospitalization and risk of mortality in patients with atrial fibrillation treated with dabigatran or warfarin in the Randomized Evaluation of Long-term Anticoagulation Therapy (RE-LY) trial  Academic Article
• Recognition, treatment, and prevention of heparin-induced thrombocytopenia: Review and update  Academic Article
• Reduction of thrombus size in murine models of thrombosis following administration of recombinant α1-proteinase inhibitor mutant proteins  Academic Article
• Reply: regarding the effect of dabigatran plasma concentrations.  Academic Article
• Response to Letter Regarding Article, “Causes of Death and Influencing Factors in Patients With Atrial Fibrillation: A Competing-Risk Analysis From the Randomized Evaluation of Long-Term Anticoagulant Therapy Study”  Academic Article
• Retention of hemostatic and immunological properties of frozen plasma and COVID ‐19 convalescent apheresis fresh‐frozen plasma produced and freeze‐dried in Canada  Academic Article
• Retention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells  Academic Article
• Reversal of dabigatran-associated major bleeding with activated prothrombin concentrate: A prospective cohort study  Academic Article
• Reversal of target-specific oral anticoagulants  Academic Article
• Risk of Cardiovascular Events and Mortality Among Elderly Patients With Reduced GFR Receiving Direct Oral Anticoagulants  Academic Article
• Risk of Stent Thrombosis and Major Bleeding with Bivalirudin Compared with Active Control: A Systematic Review and Meta-analysis of Randomized Trials  Academic Article
• Risk of recurrent venous thromboembolism or bleeding in relation to thrombophilic risk factors in patients receiving ximelagatran or placebo for long-term secondary prevention of venous thromboembolism  Academic Article
• Risks for Stroke, Bleeding, and Death in Patients With Atrial Fibrillation Receiving Dabigatran or Warfarin in Relation to the CHADS_2 Score: A Subgroup Analysis of the RE-LY Trial  Academic Article
• Rivaroxaban and Dabigatran for Suppression of Mechanical Heart Valve–Induced Thrombin Generation  Academic Article
• Safety and Efficacy of Dabigatran Compared With Warfarin for Patients Undergoing Radiofrequency Catheter Ablation of Atrial Fibrillation: A Meta-analysis  Academic Article
• Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for non-vitamin K antagonist oral anticoagulant dose adjustment  Academic Article
• Short-term dabigatran interruption before cardiac rhythm device implantation: multi-centre experience from the RE-LY trial  Academic Article
• Site-directed mutagenesis of the P2 residue of human antithrombin  Academic Article
• Strategies for development of novel antithrombotics: modulating thrombin's procoagulant and anticoagulant properties  Academic Article
• Strategies for the prevention and treatment of bleeding in patients treated with dabigatran: an update  Academic Article
• Surface modification of polydimethylsiloxane with a covalent antithrombin–heparin complex to prevent thrombosis  Academic Article
• Surface modification with an antithrombin–heparin complex for anticoagulation: Studies on a model surface with gold as substrate  Academic Article
• Synthesis of antithrombin III and alpha-1-antitrypsin by the perfused rat liver  Academic Article
• The Changing Landscape for Stroke Prevention in AF: Findings From the GLORIA-AF Registry Phase 2  Academic Article
• The Clearance of Thrombin-antithrombin and Related Serpin-enzyme Complexes from the Circulation: Role of Various Hepatocyte Receptors  Academic Article
• The Effect of Dabigatran Plasma Concentrations and Patient Characteristics on the Frequency of Ischemic Stroke and Major Bleeding in Atrial Fibrillation Patients  Academic Article
• The Effect of Heparin Adsorbed on Sepharose-Lysine on the Inactivation of Thrombin by Anti-Thrombin III  Academic Article
• The Emerging Role of Immunoregulation of Fibrinogen-Related Procoagulant Fgl2 in the Success or Spontaneous Abortion of Early Pregnancy in Mice and Humans  Academic Article
• The Long-Term Multicenter Observational Study of Dabigatran Treatment in Patients With Atrial Fibrillation (RELY-ABLE) Study  Academic Article
• The Procoagulant State of the VX-2 Tumor in Rabbit Lung In Vivo  Academic Article
• The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial  Academic Article
• The effects of chemotherapeutic agents on the regulation of thrombin on cell surfaces  Academic Article
• The evolving role of direct thrombin inhibitors in acute coronary syndromes.  Academic Article
• The inactivation of thrombin and plasmin by antithrombin III in the presence of Sepharose-heparin  Academic Article
• The mechanism of action of thrombin inhibitors.  Academic Article
• Thromboepidemiology: Identifying patients with heritable risk for thrombin-mediated thromboembolic events  Academic Article
• Timing the First Postoperative Dose of Anticoagulants  Academic Article
• Transition from apixaban to warfarin—addressing excess stroke, systemic embolism, and major bleeding  Academic Article
• Translational Success Stories  Academic Article
• Treatment of Acute Venous Thromboembolism With Dabigatran or Warfarin and Pooled Analysis  Academic Article
• Treatment of bleeding complications in patients on anticoagulant therapy  Academic Article
• Treatment of venous thromboembolism with dabigatran  Academic Article
• Treatment with dabigatran or warfarin in patients with venous thromboembolism and cancer  Academic Article
• Uptake of heparin cofactor II and antithrombin into the aorta wall after a deendothelializing injury in vivo: Comparison with the behaviors of prothrombin and fibrinogen  Academic Article
• Use of selective factor Xa inhibitors in special populations.  Academic Article
• Validation of a patient decision aid for choosing between dabigatran and warfarin for atrial fibrillation.  Academic Article
• Vasoflux, a New Anticoagulant With a Novel Mechanism of Action  Academic Article
• Vitamin K antagonist-experienced patients with a history of stroke/transient ischaemic attack who switched from warfarin to dabigatran increased their rate of recurrent stroke/transient ischaemic attack compared with those on warfarin  Academic Article
• Volutrauma activates the clotting cascade in the newborn but not adult rat  Academic Article
• Ximelagatran: the first oral direct thrombin inhibitor.  Academic Article
• Zn2+ Mediates High Affinity Binding of Heparin to the αC Domain of Fibrinogen  Academic Article
• ‘Real world’ use of non-vitamin K antagonist oral anticoagulants (NOACs): Lessons from the Dresden NOAC Registry  Academic Article