Antithrombins Concept

subject area of

• 2014 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation  Journal Articles
• d-Dimer Testing to Determine the Duration of Anticoagulation Therapy  Journal Articles
• A novel and de novo spontaneous point mutation (Glu271STOP) of the antithrombin gene results in a type I deficiency and thrombophilia  Journal Articles
• A novel antithrombin-heparin covalent complex  Journal Articles
• A novel long‐acting synthetic factor Xa inhibitor (SanOrg34006) to replace warfarin for secondary prevention in deep vein thrombosis. A Phase II evaluation  Journal Articles
• Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine—A Multicenter Trial  Journal Articles
• Activated prothrombin complex concentrate for dabigatran‐associated bleeding  Journal Articles
• Activation of factor X and prothrombin in antithrombin-III depleted plasma: The effects of heparin  Journal Articles
• Acute management of bleeding in patients on novel oral anticoagulants  Journal Articles
• Adherence to anticoagulant treatment with dabigatran in a real‐world setting  Journal Articles
• Advances in Antithrombotic Therapy: Novel Agents  Journal Articles
• Advances in the management of venous thromboembolism  Journal Articles
• Advances in the management of venous thromboembolism.  Journal Articles
• Algorithm for Rapid Exclusion of Clinically Relevant Plasma Levels of Direct Oral Anticoagulants in Patients Using the DOAC Dipstick: An Expert Consensus Paper  Journal Articles
• American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism  Journal Articles
• American Society of Hematology 2023 guidelines for management of venous thromboembolism: thrombophilia testing  Journal Articles
• Amino acid substitutions of the P2 residue of human antithrombin that either enhance or impair function  Journal Articles
• An important role for the activation peptide domain in controlling factor IX levels in the blood of haemophilia B mice  Conferences
• An open-label study of the pharmacokinetics and pharmacodynamics of dabigatran etexilate 150 mg once daily in Caucasian patients with moderate renal impairment undergoing primary unilateral elective total knee or hip replacement surgery  Journal Articles
• Analysis of Inhibition Rate Enhancement by Covalent Linkage of Antithrombin to Heparin as a Potential Predictor of Reaction Mechanism  Journal Articles
• Angiotensin-converting enzyme 2 (ACE2) levels in relation to risk factors for COVID-19 in two large cohorts of patients with atrial fibrillation  Journal Articles
• Anticoagulant mechanisms of covalent antithrombin-heparin investigated by thrombelastography  Journal Articles
• Antithrombin alfa in hereditary antithrombin deficient patients: A phase 3 study of prophylactic intravenous administration in high risk situations  Journal Articles
• Antithrombin-Heparin Covalent Complex  Journal Articles
• Antithrombin-Independent Anticoagulation by Hypersulfated Low-Molecular-Weight Heparin  Journal Articles
• Antithrombin-heparin covalent complex reduces microemboli during cardiopulmonary bypass in a pig model  Journal Articles
• Antithrombins: Their Potential as Antithrombotic Agents  Journal Articles
• Antithrombotic Agents  Journal Articles
• Antithrombotic Therapy for Coronary Artery Disease  Journal Articles
• Argatroban Anticoagulation in Patients With Heparin-Induced Thrombocytopenia  Journal Articles
• Balancing the Benefits and Risks of 2 Doses of Dabigatran Compared With Warfarin in Atrial Fibrillation  Journal Articles
• Basic coagulation tests as surrogates of dabigatran levels in a pre-operative setting: Analysis of five activated partial thromboplastin time reagents and thrombin time  Journal Articles
• Beyond Heparin and Aspirin  Journal Articles
• Biodistribution of covalent antithrombin-heparin complexes  Journal Articles
• Biologic rationale for the therapeutic role of specific antithrombins  Journal Articles
• Bivalent Binding to γA/γ′-Fibrin Engages Both Exosites of Thrombin and Protects It from Inhibition by the Antithrombin-Heparin Complex  Journal Articles
• Bivalent direct thrombin inhibitors: hirudin and bivalirudin  Journal Articles
• Bivalirudin in patients with heparin-induced thrombocytopenia undergoing percutaneous coronary intervention.  Journal Articles
• Bivalirudin versus Unfractionated Heparin during Percutaneous Coronary Intervention in Patients with Non‐ST‐Segment Elevation Acute Coronary Syndrome Initially Treated with Fondaparinux: Results from an International, Multicenter, Randomized Pilot Study (SWITCH III)  Journal Articles
• Bivalirudin, thrombin and platelets: clinical implications and future directions.  Journal Articles
• Bivalirudin: a review  Journal Articles
• Bleeding Complications in Patients with Acute Coronary Syndromes: Are They Important and How Can We Prevent Them?  Journal Articles
• Bleeding events with dabigatran or warfarin in patients with venous thromboembolism  Journal Articles
• Blood-compatible biomaterials by surface coating with a novel antithrombin–heparin covalent complex  Journal Articles
• By Increasing the Affinity of Heparin for Fibrin, Zn²⁺ Promotes the Formation of a Ternary Heparin–Thrombin–Fibrin Complex That Protects Thrombin from Inhibition by Antithrombin  Journal Articles
• Causes of Death and Influencing Factors in Patients With Atrial Fibrillation  Journal Articles
• Characterization of a highly polymorphic trinucleotide short tandem repeat within the human antithrombin gene  Journal Articles
• Chronic performance of polyurethane catheters covalently coated with ATH complex: A rabbit jugular vein model  Journal Articles
• Clinical Implications of Reversal Agents for Direct Oral Anticoagulants  Journal Articles
• Comparison of Characteristics and Outcomes of Dabigatran Versus Warfarin in Hypertensive Patients With Atrial Fibrillation (from the RE-LY Trial)  Journal Articles
• Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the Randomized Evaluation of PCI Linking Angiomax to Reduced Clinical Events [REPLACE]-1 trial)  Journal Articles
• Comparison of bleeding risk scores in patients with atrial fibrillation: insights from the RE‐LY trial  Journal Articles
• Comparison of dabigatran versus warfarin in diabetic patients with atrial fibrillation: Results from the RE-LY trial  Journal Articles
• Comparison of recombinant and plasma-derived antithrombin biodistribution in a rabbit model  Journal Articles
• Comparison of the effect of dabigatran and dalteparin on thrombus stability in a murine model of venous thromboembolism  Journal Articles
• Conditions Affecting the Responses of Human Platelets to Epinephrine  Journal Articles
• Cost-effectiveness analysis of dabigatran and anticoagulation monitoring strategies of vitamin K antagonist  Journal Articles
• Covalent antithrombin-heparin effect on thrombin-thrombomodulin and activated protein C reaction with factor V/Va  Journal Articles
• Covalent antithrombin–heparin complexes  Journal Articles
• Covalently linking heparin to antithrombin enhances prothrombinase inhibition on activated platelets  Journal Articles
• Current agents for the treatment of patients with heparin-induced thrombocytopenia  Journal Articles
• Dabigatran Persistence and Outcomes Following Discontinuation in Atrial Fibrillation Patients from the GLORIA-AF Registry  Journal Articles
• Dabigatran Reversal With Idarucizumab in Patients Requiring Urgent Surgery  Journal Articles
• Dabigatran Reversal With Idarucizumab in Patients With Renal Impairment  Journal Articles
• Dabigatran Reversal with Idarucizumab  Journal Articles
• Dabigatran Treatment of Acute Noncardioembolic Ischemic Stroke  Journal Articles
• Dabigatran Versus Warfarin  Journal Articles
• Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function  Journal Articles
• Dabigatran attenuates thrombin generation to a lesser extent than warfarin: could this explain their differential effects on intracranial hemorrhage and myocardial infarction?  Journal Articles
• Dabigatran following acute transient ischemic attack and minor stroke II (DATAS II)  Journal Articles
• Dabigatran in clinical practice: Contemporary overview of the evidence  Journal Articles
• Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial  Journal Articles
• Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve‐Induced Thrombin Generation  Journal Articles
• Dabigatran monitoring made simple?  Journal Articles
• Dabigatran reversal by idarucizumab in the setting of intracranial hemorrhage: A systematic review of the literature  Journal Articles
• Dabigatran versus Warfarin for Acute Venous Thromboembolism in Elderly or Impaired Renal Function Patients: Pooled Analysis of RE-COVER and RE-COVER II  Journal Articles
• Dabigatran versus Warfarin for Acute Venous Thromboembolism in Elderly or Impaired Renal Function Patients: Pooled Analysis of RE-COVER and RE-COVER II.  Journal Articles
• Dabigatran vs. warfarin in relation to the presence of left ventricular hypertrophy in patients with atrial fibrillation— the Randomized Evaluation of Long-term anticoagulation therapY (RE-LY) study  Journal Articles
• Dabigatran-Induced Acute Hepatitis  Journal Articles
• Dabigatran-related coagulopathy: when can we assume the effect has “worn off”?  Journal Articles
• Decreased concentration of antithrombin after preoperative therapeutic heparin does not cause heparin resistance during cardiopulmonary bypass  Journal Articles
• Defining heparin resistance: communication from the ISTH SSC Subcommittee of Perioperative and Critical Care Thrombosis and Hemostasis  Journal Articles
• Defining the heparin-binding domain of antithrombin  Journal Articles
• Definition of clinically relevant non‐major bleeding in studies of anticoagulants in atrial fibrillation and venous thromboembolic disease in non‐surgical patients: communication from the SSC of the ISTH  Journal Articles
• Delayed but not Early Treatment with DNase Reduces Organ Damage and Improves Outcome in a Murine Model of Sepsis  Journal Articles
• Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatran  Journal Articles
• Diagnosis and management of inherited and acquired thrombophilias.  Journal Articles
• Differences between perspectives of physicians and patients on anticoagulation in patients with atrial fibrillation: observational study Commentary: Varied preferences reflect the reality of clinical practice  Journal Articles
• Direct Oral Anticoagulant- or Warfarin-Related Major Bleeding  Journal Articles
• Direct Oral Anticoagulants Versus Vitamin K Antagonists in Patients Undergoing Cardioversion for Atrial Fibrillation: a Systematic Review and Meta-analysis  Journal Articles
• Direct Thrombin Inhibitors  Conferences
• Direct comparative effectiveness and safety between non-vitamin K antagonist oral anticoagulants for stroke prevention in nonvalvular atrial fibrillation: a systematic review and meta-analysis of observational studies  Journal Articles
• Direct thrombin inhibitors for treatment of arterial thrombosis: potential differences between bivalirudin and hirudin  Conferences
• Direct thrombin inhibitors in acute coronary syndromes: effect in patients undergoing early percutaneous coronary intervention  Journal Articles
• Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data  Journal Articles
• Direct thrombin inhibitors in cardiovascular disease  Journal Articles
• Discordance between the anti-Xa activity and the antithrombotic activity of an ultra-low molecular weight heparin fraction  Journal Articles
• Discrepancy between antithrombin activity methods revealed in Antithrombin Stockholm: do factor Xa–based methods overestimate antithrombin activity in some patients?  Journal Articles
• Do sick newborn infants benefit from participation in a randomized clinical trial?  Journal Articles
• Dual surface modification of polydimethylsiloxane (PDMS) with antithrombin-heparin complex (ATH) and tissue plasminogen activator (t-PA) for enhanced antithrombotic activity.  Journal Articles
• Effect of Covalent Serpin–Heparinoid Complexes on Plasma Thrombin Generation on Fetal Distal Lung Epithelium  Journal Articles
• Effect of covalent antithrombin-heparin complex on developmental mechanisms in the lung  Journal Articles
• Effect of covalent antithrombin-heparin on activated protein C inactivation by protein C inhibitor  Journal Articles
• Effect of endothelium on the anticoagulant activity of a covalent antithrombin-heparin complex.  Journal Articles
• Effect of substrate and fibrin polymerization inhibitor on determination of plasma thrombin generation in vitro  Journal Articles
• Effects of dabigatran according to age in atrial fibrillation  Journal Articles
• Efficacy of dabigatran versus warfarin in patients with acute venous thromboembolism in the presence of thrombophilia: Findings from RE-COVER^®, RE-COVER™ II, and RE-MEDY™  Journal Articles
• Emergency care of patients receiving non-vitamin K antagonist oral anticoagulants  Journal Articles
• Enhanced TRAP-induced platelet aggregation with dabigatran — Clinical perspective  Journal Articles
• Establishing Therapeutic Equivalence of Complex Pharmaceuticals: The Case of Dabigatran  Journal Articles
• Evaluation of Potential Early Markers of Chorioamnionitis Associated with Preterm Premature Ruptured Membranes  Journal Articles
• Exosites 1 and 2 Are Essential for Protection of Fibrin-bound Thrombin from Heparin-catalyzed Inhibition by Antithrombin and Heparin Cofactor II  Journal Articles
• Factor Xa or thrombin: Is thrombin a better target?  Conferences
• Genetic linkage studies in antithrombin‐deficient kindreds using a highly polymorphic trinucleotide short tandem repeat (str) within the human antithrombin gene  Journal Articles
• HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions  Journal Articles
• HS3ST1 genotype regulates antithrombin's inflammomodulatory tone and associates with atherosclerosis  Journal Articles
• Hemodialysis for the treatment of dabigatran‐associated bleeding: a case report and systematic review  Journal Articles
• Hemorrhagic complications in association with percutaneous coronary intervention: can the risk be attenuated?  Journal Articles
• Heparin and low molecular weight heparins as scaffolds for assembling antithrombin and serine proteases  Journal Articles
• Heparin-induced thrombocytopenia and its treatment.  Conferences
• Hirudin and thrombosis prophylaxis  Journal Articles
• How I Diagnose and Manage HIT  Journal Articles
• How I treat target-specific oral anticoagulant–associated bleeding  Journal Articles
• How to use unfractionated heparin to treat neonatal thrombosis in clinical practice  Journal Articles
• Hypercoagulability.  Journal Articles
• Hypercoagulable States  Journal Articles
• Hypersulfated Low Molecular Weight Heparin with Reduced Affinity for Antithrombin Acts as an Anticoagulant by Inhibiting Intrinsic Tenase and Prothrombinase  Journal Articles
• Idarucizumab  Journal Articles
• Idarucizumab for dabigatran overdose  Journal Articles
• Immobilization of an antithrombin–heparin complex on gold: Anticoagulant properties and platelet interactions  Journal Articles
• Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex  Journal Articles
• Impact of SERPINC1 mutation on thrombotic phenotype in children with congenital antithrombin deficiency—first analysis of the International Society on Thrombosis and Haemostasis pediatric antithrombin deficiency database and biorepository  Journal Articles
• Importance of infarct topography in determination of stroke mechanism and recurrence risk: a post-hoc analysis of the dabigatran acute treatment of stroke trial.  Journal Articles
• In DVT, oral DTIs and factor Xa inhibitors reduce major bleeding but not recurrent VTE vs. conventional anticoagulants  Journal Articles
• In vivo rabbit acute model tests of polyurethane catheters coated with a novel antithrombin-heparin covalent complex  Journal Articles
• In-vitro assessment of the effect of dabigatran on thrombosis of adult and neonatal plasma  Journal Articles
• Incidence of Direct Oral Anticoagulant Prescriptions in Kidney Transplant Recipients in Ontario, Canada  Journal Articles
• Individual Treatment Effect Estimation of 2 Doses of Dabigatran on Stroke and Major Bleeding in Atrial Fibrillation  Journal Articles
• Inhibition of Fibrin-Bound Thrombin by a Covalent Antithrombin-Heparin Complex  Journal Articles
• Inhibition of plasmin generation in plasma by heparin, low molecular weight heparin, and a covalent antithrombin–heparin complex  Journal Articles
• Inhibition of the prothrombinase complex on red blood cells by heparin and covalent antithrombin-heparin complex  Journal Articles
• Insights into the role of thrombin in the pathogenesis of recurrent ischaemia after acute coronary syndrome  Journal Articles
• Interactions of antithrombin and proteins in the plasma contact activation system with immobilized functional heparin  Journal Articles
• Interactions of heparin and a covalently-linked antithrombin-heparin complex with components of the fibrinolytic system  Journal Articles
• Intracellular events determine the fate of antithrombin Utah  Journal Articles
• Intravascular Targeting of a New Anticoagulant Heparin Compound  Journal Articles
• Investigation of the Anticoagulant Mechanisms of a Covalent Antithrombin-Heparin Complex  Journal Articles
• Is there really misuse and abuse of dabigatran?  Journal Articles
• Isoform composition of antithrombin in a covalent antithrombin–heparin complex  Journal Articles
• Key references: Protein C, protein S, and antithrombin deficiencies.  Journal Articles
• Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants  Journal Articles
• Laboratory Measurement of the Anticoagulant Activity of the Non–Vitamin K Oral Anticoagulants  Journal Articles
• Laboratory Monitoring of Non–Vitamin K Antagonist Oral Anticoagulant Use in Patients With Atrial Fibrillation  Journal Articles
• Letter by Van de Werf et al Regarding Article, “Using Dabigatran in Patients With Stroke: A Practical Guide for Clinicians”  Journal Articles
• Life-Threatening Thrombosis in Mice With Targeted Arg48-to-Cys Mutation of the Heparin-Binding Domain of Antithrombin  Journal Articles
• Long-Term Oral Anticoagulant Therapy in Patients With Unstable Angina or Suspected Non–Q-Wave Myocardial Infarction  Journal Articles
• Long-term evaluation of dabigatran 150 vs. 110 mg twice a day in patients with non-valvular atrial fibrillation  Journal Articles
• Management and Outcomes of Major Bleeding During Treatment With Dabigatran or Warfarin  Journal Articles
• Management of Anticoagulation Around Pacemaker and Defibrillator Surgery  Journal Articles
• Management of Patients with Acute Coronary Syndromes  Journal Articles
• Management of Patients with Hereditary Hypercoagulable Disorders  Journal Articles
• Management of heparin-induced thrombocytopenia: a critical comparison of lepirudin and argatroban  Journal Articles
• Measurement of Dabigatran Drug Levels to Manage Patients Taking Interacting Drugs: A Case Report  Journal Articles
• Measuring Dabigatran Levels: What Tests Are Available and What Still Needs to Be Done?  Journal Articles
• Mechanism of Catalysis of Inhibition of Factor IXa by Antithrombin in the Presence of Heparin or Pentasaccharide  Journal Articles
• Mechanism of inhibition of the prothrombinase complex by a covalent antithrombin-heparin complex  Journal Articles
• Mechanisms for the Anticoagulant Effects of Synthetic Antithrombins  Journal Articles
• Meta-Analysis Comparing Bivalirudin Versus Heparin Monotherapy on Ischemic and Bleeding Outcomes After Percutaneous Coronary Intervention  Journal Articles
• Meta-Analysis of Effects of Bivalirudin Versus Heparin on Myocardial Ischemic and Bleeding Outcomes After Percutaneous Coronary Intervention  Journal Articles
• Mixing study to diagnose heparin‐resistance caused by functional antithrombin deficiency  Journal Articles
• Modification of Polyurethane Surface with an Antithrombin–Heparin Complex for Blood Contact: Influence of Molecular Weight of Polyethylene Oxide Used as a Linker/Spacer  Journal Articles
• Molecular basis of inherited human antithrombin deficiency  Journal Articles
• Mortality outcomes in patients receiving direct oral anticoagulants: a systematic review and meta‐analysis of randomized controlled trials  Journal Articles
• Mutation of Any Site of N-Linked Glycosylation Accelerates the In Vivo Clearance of Recombinant Rabbit Antithrombin  Journal Articles
• Myocardial Ischemic Events in Patients With Atrial Fibrillation Treated With Dabigatran or Warfarin in the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) Trial  Journal Articles
• NOAC monitoring, reversal agents, and post-approval safety and effectiveness evaluation: A cardiac safety research consortium think tank  Journal Articles
• New anticoagulants  Conferences
• New anticoagulants.  Journal Articles
• Nonheparin Anticoagulants for Heparin-Induced Thrombocytopenia  Journal Articles
• Novel oral anticoagulants in gastroenterology practice  Journal Articles
• Only high levels of dabigatran attenuate catheter thrombosis in vitro and in rabbits  Journal Articles
• Oral Anticoagulant Therapy  Journal Articles
• Overview of the New Oral Anticoagulants  Journal Articles
• Parenteral Anticoagulants  Journal Articles
• Perioperative Management of Dabigatran  Journal Articles
• Perioperative management of patients who are receiving a novel oral anticoagulant  Journal Articles
• Periprocedural Management and Approach to Bleeding in Patients Taking Dabigatran  Journal Articles
• Persistence With Dabigatran Therapy at 2 Years in Patients With Atrial Fibrillation  Journal Articles
• Plasminogen II accumulates five times faster than plasminogen I at the site of a balloon de-endothelializing injury in vivo to the rabbit aorta: Comparison with other hemostatic proteins  Journal Articles
• Polyurethane modified with an antithrombin‐heparin complex via polyethylene oxide linker/spacers: Influence of PEO molecular weight and PEO‐ATH bond on catalytic and direct anticoagulant functions  Journal Articles
• Potent Antithrombin Activity and Delayed Clearance From the Circulation Characterize Recombinant Hirudin Genetically Fused to Albumin  Journal Articles
• Practical management of bleeding in patients receiving non-vitamin K antagonist oral anticoagulants  Journal Articles
• Preference-Based Antithrombotic Therapy in Atrial Fibrillation: Implications for Clinical Decision Making  Journal Articles
• Preoperative antithrombin supplementation in cardiac surgery: A randomized controlled trial  Journal Articles
• Preparation and partial characterization of human plasma depleted of antithrombin-III by heparin-sepharose affinity chromatography  Journal Articles
• Preventing Cardioembolic Stroke in Atrial Fibrillation with Dabigatran  Journal Articles
• Prevention and treatment of thrombosis: novel strategies arising from our understanding the healthy endothelium.  Journal Articles
• Proceedings: Platelet survival, fibrinolytic activity, antithrombin II (AT III) level and fibrinogen survival in venous thromboembolism (VTE).  Journal Articles
• Profile of patients diagnosed with acute venous thromboembolism in routine practice according to age and renal function: RE-COVERY DVT/PE study  Journal Articles
• Progressive, Fatal Thrombosis Associated With Heparin-Induced Thrombocytopenia After Cardiac Surgery Despite “Therapeutic” Anticoagulation With Argatroban: Potential Role for PTT and ACT Confounding  Journal Articles
• Protein adsorption on polyurethane catheters modified with a novel antithrombin‐heparin covalent complex  Journal Articles
• RE-COVERY DVT/PE: Rationale and design of a prospective observational study of acute venous thromboembolism with a focus on dabigatran etexilate  Journal Articles
• Randomized Comparison of Direct Thrombin Inhibition Versus Heparin in Conjunction With Fibrinolytic Therapy for Acute Myocardial Infarction: Results From the GUSTO-IIb Trial  Journal Articles
• Randomized comparison of direct thrombin inhibition versus heparin in conjunction with fibrinolytic therapy for acute myocardial infarction: results from the GUSTO-IIb Trial. Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes (GUSTO-IIb) Investigators.  Journal Articles
• Reactivation of coagulation after stopping infusions of recombinant hirudin and unfractionated heparin in unstable angina and myocardial infarction without ST elevation: results of a randomized trial  Journal Articles
• Reactivation of ischemic events in acute coronary syndromes: results from GUSTO-IIb  Journal Articles
• Reactivation of ischemic events in acute coronary syndromes: results from GUSTO-IIb. Gobal Use of Strategies To Open occluded arteries in acute coronary syndromes.  Journal Articles
• Real-world variability in dabigatran levels in patients with atrial fibrillation: reply  Journal Articles
• Real‐world variability in dabigatran levels in patients with atrial fibrillation  Journal Articles
• Reasons for hospitalization and risk of mortality in patients with atrial fibrillation treated with dabigatran or warfarin in the Randomized Evaluation of Long-term Anticoagulation Therapy (RE-LY) trial  Journal Articles
• Recognition, treatment, and prevention of heparin-induced thrombocytopenia: Review and update  Journal Articles
• Recommendation on the nomenclature for anticoagulants: updated communication from the International Society on Thrombosis and Haemostasis Scientific and Standardization Commitee on the Control of Anticoagulation  Journal Articles
• Reduction of thrombus size in murine models of thrombosis following administration of recombinant α1-proteinase inhibitor mutant proteins  Journal Articles
• Reply: regarding the effect of dabigatran plasma concentrations.  Journal Articles
• Response to Letter Regarding Article, “Causes of Death and Influencing Factors in Patients With Atrial Fibrillation: A Competing-Risk Analysis From the Randomized Evaluation of Long-Term Anticoagulant Therapy Study”  Journal Articles
• Retention of hemostatic and immunological properties of frozen plasma and COVID‐19 convalescent apheresis fresh‐frozen plasma produced and freeze‐dried in Canada  Journal Articles
• Retention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells  Journal Articles
• Reversal of dabigatran-associated major bleeding with activated prothrombin concentrate: A prospective cohort study  Journal Articles
• Risk Factors for Intracerebral Hemorrhage in Patients With Atrial Fibrillation on Non–Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention  Journal Articles
• Risk of Cardiovascular Events and Mortality Among Elderly Patients With Reduced GFR Receiving Direct Oral Anticoagulants  Journal Articles
• Risk of Stent Thrombosis and Major Bleeding with Bivalirudin Compared with Active Control: A Systematic Review and Meta-analysis of Randomized Trials  Journal Articles
• Risk of recurrent venous thromboembolism or bleeding in relation to thrombophilic risk factors in patients receiving ximelagatran or placebo for long‐term secondary prevention of venous thromboembolism  Journal Articles
• Risks for Stroke, Bleeding, and Death in Patients With Atrial Fibrillation Receiving Dabigatran or Warfarin in Relation to the CHADS_2 Score: A Subgroup Analysis of the RE-LY Trial  Journal Articles
• Rivaroxaban and Dabigatran for Suppression of Mechanical Heart Valve–Induced Thrombin Generation  Journal Articles
• Safety and Efficacy of Dabigatran Compared With Warfarin for Patients Undergoing Radiofrequency Catheter Ablation of Atrial Fibrillation: A Meta-analysis  Journal Articles
• Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for non‐vitamin K antagonist oral anticoagulant dose adjustment  Journal Articles
• Short-term dabigatran interruption before cardiac rhythm device implantation: multi-centre experience from the RE-LY trial  Journal Articles
• Site‐directed mutagenesis of the P2 residue of human antithrombin  Journal Articles
• Strategies for the prevention and treatment of bleeding in patients treated with dabigatran: an update  Journal Articles
• Surface modification of polydimethylsiloxane with a covalent antithrombin–heparin complex to prevent thrombosis  Journal Articles
• Surface modification with an antithrombin–heparin complex for anticoagulation: Studies on a model surface with gold as substrate  Journal Articles
• Synthesis of antithrombin III and alpha-1-antitrypsin by the perfused rat liver  Journal Articles
• THE EFFECTS OF DNASE I AND LOW-MOLECULAR-WEIGHT HEPARIN IN A MURINE MODEL OF POLYMICROBIAL ABDOMINAL SEPSIS  Journal Articles
• The Changing Landscape for Stroke Prevention in AF: Findings From the GLORIA-AF Registry Phase 2  Journal Articles
• The Clearance of Thrombin-antithrombin and Related Serpin-enzyme Complexes from the Circulation: Role of Various Hepatocyte Receptors  Journal Articles
• The Effect of Dabigatran Plasma Concentrations and Patient Characteristics on the Frequency of Ischemic Stroke and Major Bleeding in Atrial Fibrillation Patients  Journal Articles
• The Effect of Heparin Adsorbed on Sepharose-Lysine on the Inactivation of Thrombin by Anti-Thrombin III  Journal Articles
• The Emerging Role of Immunoregulation of Fibrinogen‐Related Procoagulant Fgl2 in the Success or Spontaneous Abortion of Early Pregnancy in Mice and Humans  Journal Articles
• The Long-Term Multicenter Observational Study of Dabigatran Treatment in Patients With Atrial Fibrillation (RELY-ABLE) Study  Journal Articles
• The Procoagulant State of the VX-2 Tumor in Rabbit Lung In Vivo  Journal Articles
• The Risk of Acute Kidney Injury with Oral Anticoagulants in Elderly Adults with Atrial Fibrillation  Journal Articles
• The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial  Journal Articles
• The effects of chemotherapeutic agents on the regulation of thrombin on cell surfaces  Journal Articles
• The evolving role of direct thrombin inhibitors in acute coronary syndromes  Journal Articles
• The evolving role of direct thrombin inhibitors in acute coronary syndromes.  Journal Articles
• The inactivation of thrombin and plasmin by antithrombin III in the presence of Sepharose-heparin  Journal Articles
• The mechanism of action of thrombin inhibitors.  Journal Articles
• Thromboepidemiology: Identifying patients with heritable risk for thrombin-mediated thromboembolic events  Journal Articles
• Timing the First Postoperative Dose of Anticoagulants  Journal Articles
• Transition from apixaban to warfarin—addressing excess stroke, systemic embolism, and major bleeding  Journal Articles
• Translational Success Stories  Journal Articles
• Treatment of Acute Venous Thromboembolism With Dabigatran or Warfarin and Pooled Analysis  Journal Articles
• Treatment of bleeding complications in patients on anticoagulant therapy  Journal Articles
• Treatment of venous thromboembolism with dabigatran  Journal Articles
• Treatment with dabigatran or warfarin in patients with venous thromboembolism and cancer  Journal Articles
• Uptake of heparin cofactor II and antithrombin into the aorta wall after a deendothelializing injury in vivo: Comparison with the behaviors of prothrombin and fibrinogen  Journal Articles
• Use of selective factor Xa inhibitors in special populations.  Journal Articles
• Validation of a patient decision aid for choosing between dabigatran and warfarin for atrial fibrillation.  Journal Articles
• Vasoflux, a New Anticoagulant With a Novel Mechanism of Action  Journal Articles
• Vitamin K antagonist-experienced patients with a history of stroke/transient ischaemic attack who switched from warfarin to dabigatran increased their rate of recurrent stroke/transient ischaemic attack compared with those on warfarin  Journal Articles
• Volutrauma activates the clotting cascade in the newborn but not adult rat  Journal Articles
• Ximelagatran: the first oral direct thrombin inhibitor  Journal Articles
• Ximelagatran: the first oral direct thrombin inhibitor.  Journal Articles
• Zn2+ Mediates High Affinity Binding of Heparin to the αC Domain of Fibrinogen  Journal Articles
• ‘Real world’ use of non-vitamin K antagonist oral anticoagulants (NOACs): Lessons from the Dresden NOAC Registry  Journal Articles