Journal article
Risk of Cardiovascular Events and Mortality Among Elderly Patients With Reduced GFR Receiving Direct Oral Anticoagulants
Abstract
RATIONALE & OBJECTIVE: Evidence for the efficacy of direct oral anticoagulants (DOACs) to prevent cardiovascular (CV) events and mortality in older individuals with a low estimated glomerular filtration rate (eGFR) is lacking. We sought to characterize the association of oral anticoagulant use with CV morbidity in elderly patients with or without reductions in eGFRs, comparing DOACs with vitamin K antagonists (VKAs).
STUDY DESIGN: Population-bas…
Authors
Ashley J; McArthur E; Bota S; Harel Z; Battistella M; Molnar AO; Jun M; Badve SV; Garg AX; Manuel D
Journal
American Journal of Kidney Diseases, Vol. 76, No. 3, pp. 311–320
Publisher
Elsevier
Publication Date
September 2020
DOI
10.1053/j.ajkd.2020.02.446
ISSN
0272-6386
Associated Experts
Fields of Research (FoR)
Sustainable Development Goals (SDG)
Medical Subject Headings (MeSH)
AgedAged, 80 and overAntithrombinsBrain IschemiaCause of DeathComorbidityDabigatranFemaleGlomerular Filtration RateHemorrhageHumansMaleMortalityMyocardial InfarctionMyocardial RevascularizationOntarioProcedures and Techniques UtilizationPropensity ScoreProportional Hazards ModelsPyrazolesPyridonesRenal Insufficiency, ChronicRetrospective StudiesRivaroxabanThrombophiliaVitamin K