Journal article
Management and Outcomes of Major Bleeding During Treatment With Dabigatran or Warfarin
Abstract
BACKGROUND: The aim of this study was to compare the management and prognosis of major bleeding in patients treated with dabigatran or warfarin.
METHODS AND RESULTS: Two independent investigators reviewed bleeding reports from 1034 individuals with 1121 major bleeds enrolled in 5 phase III trials comparing dabigatran with warfarin in 27 419 patients treated for 6 to 36 months. Patients with major bleeds on dabigatran (n=627 of 16 755) were …
Authors
Majeed A; Hwang H-G; Connolly SJ; Eikelboom JW; Ezekowitz MD; Wallentin L; Brueckmann M; Fraessdorf M; Yusuf S; Schulman S
Journal
Circulation, Vol. 128, No. 21, pp. 2325–2332
Publisher
Wolters Kluwer
Publication Date
November 19, 2013
DOI
10.1161/circulationaha.113.002332
ISSN
0009-7322