Journal article
Angiotensin-converting enzyme 2 (ACE2) levels in relation to risk factors for COVID-19 in two large cohorts of patients with atrial fibrillation
Abstract
AIMS: The global COVID-19 pandemic is caused by the SARS-CoV-2 virus entering human cells using angiotensin-converting enzyme 2 (ACE2) as a cell surface receptor. ACE2 is shed to the circulation, and a higher plasma level of soluble ACE2 (sACE2) might reflect a higher cellular expression of ACE2. The present study explored the associations between sACE2 and clinical factors, cardiovascular biomarkers, and genetic variability.
METHODS AND …
Authors
Wallentin L; Lindbäck J; Eriksson N; Hijazi Z; Eikelboom JW; Ezekowitz MD; Granger CB; Lopes RD; Yusuf S; Oldgren J
Journal
European Heart Journal, Vol. 41, No. 41, pp. 4037–4046
Publisher
Oxford University Press (OUP)
Publication Date
November 1, 2020
DOI
10.1093/eurheartj/ehaa697
ISSN
0195-668X