Tumor Suppressor Proteins
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A Gene Variant in CERS2 Is Associated with Rate of Increase in Albuminuria in Patients with Diabetes from ONTARGET and TRANSCEND Academic Article
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A Role of p73 in Mitotic Exit Academic Article
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A novel nonsense mutation in TUSC3 is responsible for non-syndromic autosomal recessive mental retardation in a consanguineous Iranian family Academic Article
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A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients. Academic Article
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ATM activation is accompanied with earlier stages of prostate tumorigenesis Academic Article
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ATM activity contributes to the tumor-suppressing functions of p14ARF Academic Article
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ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes Academic Article
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ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence Academic Article
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ATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance Academic Article
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Aberrant interferon-signaling is associated with aggressive chronic lymphocytic leukemia Academic Article
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Activation of the Hedgehog Signaling Pathway in the Developing Lens Stimulates EctopicFoxE3Expression and Disruption in Fiber Cell Differentiation Academic Article
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Aging, oxidative responses, and proliferative capacity in cultured mouse aortic smooth muscle cells Academic Article
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Amplification of the prolactin receptor gene in mammary lobular neoplasia Academic Article
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An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity Academic Article
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Analysis of p73 expression pattern in acute myeloid leukemias: lack of ΔN-p73 expression is a frequent feature of acute promyelocytic leukemia Academic Article
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Atypical Teratoid Rhabdoid Tumors (ATRTs): The British Columbia's Children's Hospital's Experience, 1986-2006 Academic Article
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Blood flow reprograms lymphatic vessels to blood vessels Academic Article
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Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation Academic Article
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CYB5D2 displays tumor suppression activities towards cervical cancer Academic Article
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Cell of Origin in AML: Susceptibility to MN1-Induced Transformation Is Regulated by the MEIS1/AbdB-like HOX Protein Complex Academic Article
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Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73 Academic Article
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Che-1 Promotes Tumor Cell Survival by Sustaining Mutant p53 Transcription and Inhibiting DNA Damage Response Activation Academic Article
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Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21WAF1/CIP1 and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity Academic Article
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Compromised genomic integrity impedes muscle growth after Atrx inactivation Academic Article
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Current status and future innovations of hormonal agents, chemotherapy and investigational agents in endometrial cancer Academic Article
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DNA Damage-Dependent Acetylation of p73 Dictates the Selective Activation of Apoptotic Target Genes Academic Article
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Decreased levels of the cell-cycle inhibitor p27Kip1 protein: Prognostic implications in primary breast cancer Academic Article
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Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas Academic Article
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Differential Regulation of Components of the Ubiquitin-Proteasome Pathway during Lens Cell Differentiation Academic Article
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Differential expression pattern of ZAC in developing mouse and human pancreas Academic Article
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ERK Activation Mediates Cell Cycle Arrest and Apoptosis after DNA Damage Independently of p53 Academic Article
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Editorial Comment on: Metastin Inhibits Migration and Invasion of Renal Cell Carcinoma with Overexpression of Metastin Receptor Academic Article
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Enteric neurons synthesize netrins and are essential for the development of the vagal sensory innervation of the fetal gut Academic Article
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Expression of p27 in Residual Rectal Cancer after Preoperative Chemoradiation Predicts Long-term Outcome Academic Article
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Expression of the β4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells Academic Article
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Extrinsic signals determine myeloid-erythroid lineage switch in MN1 leukemia Academic Article
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From p63 to p53 across p73 Academic Article
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Functional role of BAALC in leukemogenesis Academic Article
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Gender, mutant p53 and PML: A growing “affaire” in tumor suppression and oncogenesis Academic Article
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Guidance signalling regulates leading edge behaviour during collective cell migration of cardiac cells in Drosophila Academic Article
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Host Cell Factor-1 Interacts with and Antagonizes Transactivation by the Cell Cycle Regulatory Factor Miz-1 Academic Article
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IQGAP2, A candidate tumour suppressor of prostate tumorigenesis Academic Article
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Identification of Direct p73 Target Genes Combining DNA Microarray and Chromatin Immunoprecipitation Analyses Academic Article
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Identification of an ataxia telangiectasia-mutated protein mediated surveillance system to regulate Bcl-2 overexpression Academic Article
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Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma: results of the HGG-2006 phase I/II trial Academic Article
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Integrins Regulate Responsiveness to Slit Repellent Signals Academic Article
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Interaction of c-Abl and p73α and their collaboration to induce apoptosis Academic Article
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Interaction of mutant p53 with p73: A Surface Plasmon Resonance and Atomic Force Spectroscopy study Academic Article
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Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells Academic Article
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Laminin terminates the Netrin/DCC mediated attraction of vagal sensory axons Academic Article
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MN1 C-terminal truncation syndrome is a novel neurodevelopmental and craniofacial disorder with partial rhombencephalosynapsis Academic Article
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MRE11–RAD50–NBS1 and ATM function as co-mediators of TRF1 in telomere length control Academic Article
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Mammalian target of rapamycin complex 1 activation sensitizes human glioma cells to hypoxia-induced cell death Academic Article
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Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation Academic Article
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Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK Academic Article
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Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13 Academic Article
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Monoclonal antibodies raised against Xenopus p53 interact with human p73 Academic Article
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Multicenter evaluation of an amperometric immunosensor for plasma fatty acid-binding protein: Academic Article
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Neonatal diabetes, with hypoplastic pancreas, intestinal atresia and gall bladder hypoplasia: search for the aetiology of a new autosomal recessive syndrome Academic Article
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Netrin/DCC-mediated attraction of vagal sensory axons to the fetal mouse gut Academic Article
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PML has a predictive role in tumor cell permissiveness to interferon-sensitive oncolytic viruses Academic Article
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PML, YAP, and p73 Are Components of a Proapoptotic Autoregulatory Feedback Loop Academic Article
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Phase II study of targeted therapy with temozolomide in acute myeloid leukaemia and high-risk myelodysplastic syndrome patients pre-screened for low O6-methylguanine DNA methyltransferase expression Academic Article
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Physical Interaction with Human Tumor-derived p53 Mutants Inhibits p63 Activities Academic Article
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Physical Interaction with Yes-associated Protein Enhances p73 Transcriptional Activity Academic Article
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Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73 Academic Article
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Pin1 Links the Activities of c-Abl and p300 in Regulating p73 Function Academic Article
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Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination Academic Article
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Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53 Academic Article
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Regulation of the cell cycle in response to inhibition of mitochondrial generated energy Academic Article
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Roles for MSI2 and PROX1 in hematopoietic stem cell activity Academic Article
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S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation Academic Article
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S100A7 (psoriasin) expression is associated with aggressive features and alteration of Jab1 in ductal carcinoma in situof the breast Academic Article
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Signal transducer and activator of transcription 3 and 5 regulate system Xc- and redox balance in human breast cancer cells Academic Article
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TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer Academic Article
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Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs OXPHOS and prostate cancer metastatic spread Academic Article
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Telomere maintenance by telomerase and by recombination can coexist in human cells Academic Article
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The Hippo Tumor Suppressor Pathway: A Brainstorming WorkshopA report on the research meeting “The Hippo Tumor Suppressor Pathway: A Brainstorming Workshop” sponsored mainly by the Regina Elena Cancer Center and the Nicola Foundation and held in Rome, Italy, on 22 and 23 April 2009. Academic Article
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The Prognostic Implication of the Basal-Like (Cyclin Ehigh/p27low/p53+/Glomeruloid-Microvascular-Proliferation+) Phenotype of
BRCA1
-Related Breast Cancer Academic Article
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The Transcriptional Coactivator Yes-Associated Protein Drives p73 Gene-Target Specificity in Response to DNA Damage Academic Article
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The Transcriptional Repressor ZEB Regulates p73 Expression at the Crossroad between Proliferation and Differentiation Academic Article
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The cytoplasmic domain is critical to the tumor suppressor activity of TSLC1 in non-small cell lung cancer. Academic Article
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The disruption of the protein complex mutantp53/p73 increases selectively the response of tumor cells to anticancer drugs Academic Article
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The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells Academic Article
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Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1) Academic Article
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Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73 Academic Article
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Tumor Suppressor in Lung Cancer (TSLC)1 Suppresses Epithelial Cell Scattering and Tubulogenesis Academic Article
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YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer Academic Article
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YAP1 Meets Tumor Suppression Academic Article
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YAP: At the crossroad between transformation and tumor suppression Academic Article
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p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor Academic Article
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p63 regulation by microRNAs Academic Article
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p73 Is Regulated by Phosphorylation at the G2/M Transition Academic Article
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p73 and p63: Why Do We Still Need Them? Academic Article
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p73-Mediated Chemosensitivity: A Preferential Target of Oncogenic Mutant p53 Academic Article
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p73-induced apoptosis: A question of compartments and cooperation Academic Article
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ΔN-p73 is a transcriptional target of the PML/RARα oncogene in myeloid differentiation Academic Article
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α-Mannosidase 2C1 attenuates PTEN function in prostate cancer cells Academic Article
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δEF1 repressor controls selectively p53 family members during differentiation Academic Article