Sample Size Concept

subject area of

• (Sample) Size Matters! An Examination of Sample Size From the SPRINT Trial Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients With Tibial Fractures  Academic Article
• A MAP-Based Image Interpolation Method via Viterbi Decoding of Markov Chains of Interpolation Functions  Academic Article
• A Meta-Analytic Review of the Effect of Exercise on Smoking Cessation  Academic Article
• A Perioperative Smoking Cessation Intervention with Varenicline  Academic Article
• A Systematic Review of Power and Sample Size Reporting in Randomized Controlled Trials within Plastic Surgery  Academic Article
• A Systematic Review of Surgical Randomized Controlled Trials  Academic Article
• A closer look at the distribution of number needed to treat (NNT): a Bayesian approach  Academic Article
• A comparison of a new multinomial stopping rule with stopping rules of fleming and gehan in single arm phase II cancer clinical trials  Academic Article
• A comparison of methods to detect publication bias in meta-analysis  Academic Article
• A genome-wide linkage and association scan reveals novel loci for autism  Academic Article
• A meta-research study of randomized controlled trials found infrequent and delayed availability of protocols  Academic Article
• A practitioner's guide to developing critical appraisal skills  Academic Article
• A process evaluation accompanying an attempted randomized controlled trial of an evidence service for health system policymakers  Academic Article
• A randomised controlled trial assessing the use of citalopram, sertraline, fluoxetine and mirtazapine in preventing relapse in primary care patients who are taking long-term maintenance antidepressants (ANTLER: ANTidepressants to prevent reLapse in dEpRession): study protocol for a randomised controlled trial  Academic Article
• A randomized ablation-based atrial fibrillation rhythm control versus rate control trial in patients with heart failure and high burden atrial fibrillation: The RAFT-AF trial rationale and design  Academic Article
• A randomized controlled trial of resistance exercise in individuals with ALS  Academic Article
• A randomized trial to assess the impact of an antithrombotic decision aid in patients with nonvalvular atrial fibrillation: the DAAFI trial protocol [ISRCTN14429643]  Academic Article
• A small p-value from an observed data is not evidence of adequate power for future similar-sized studies: A cautionary note  Academic Article
• A stepped wedge design for testing an effect of intranasal insulin on cognitive development of children with Phelan-McDermid syndrome: A comparison of different designs  Academic Article
• A systematic review and meta-analysis of sample size methodology for traumatic hemorrhage trials  Academic Article
• A systematic review of the reporting of sample size calculations and corresponding data components in observational functional magnetic resonance imaging studies  Academic Article
• ACCOUNTING FOR BETWEEN-STUDY VARIATION IN INCREMENTAL NET BENEFIT IN VALUE OF INFORMATION METHODOLOGY  Academic Article
• Accounting for treatment by center interaction in sample size determinations and the use of surrogate outcomes in the pessary for the prevention of preterm birth trial: a simulation study  Academic Article
• Adding Gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty  Academic Article
• Advanced statistics: Understanding Medical Record Review (MRR) Studies  Academic Article
• Advances in Understanding “High on-Treatment Platelet Reactivity”  Academic Article
• Alcohol Consumption and Endometrial Cancer: Some Unresolved Issues  Academic Article
• Ambulatory Toxicity Management (AToM) in patients receiving adjuvant or neo-adjuvant chemotherapy for early stage breast cancer - a pragmatic cluster randomized trial protocol  Academic Article
• An empirical study using permutation-based resampling in meta-regression  Academic Article
• An improved method for analysis of interrupted time series (ITS) data: accounting for patient heterogeneity using weighted analysis  Academic Article
• An opportunity cost approach to sample size calculation in cost-effectiveness analysis  Academic Article
• Analysis and reporting of stratified cluster randomized trials—a systematic survey  Academic Article
• Analysis, Sample Size, and Power for Estimating Incremental Net Health Benefit from Clinical Trial Data  Academic Article
• Apparently conclusive meta-analyses may be inconclusive—Trial sequential analysis adjustment of random error risk due to repetitive testing of accumulating data in apparently conclusive neonatal meta-analyses  Academic Article
• Are injuries correlated? Interpreting the intraclass correlation coefficient  Academic Article
• Are large simple trials for dementia prevention possible?  Academic Article
• Assessing Arm Volume in People During and After Treatment for Breast Cancer: Reliability and Convergent Validity of the LymphaTech System  Academic Article
• Assessment and Implication of Prognostic Imbalance in Randomized Controlled Trials with a Binary Outcome – A Simulation Study  Academic Article
• Autism spectrum disorder: When biochemical and genetic profiles don't match — Is sample size and selection bias the culprit?  Academic Article
• Bayesian methods for pilot studies  Academic Article
• Brief Communication: Preoperative Anticoagulant Activity after Bridging Low-Molecular-Weight Heparin for Temporary Interruption of Warfarin  Academic Article
• CHALLENGES IN CURRENT ADULT FISH LABORATORY REPRODUCTIVE TESTS: SUGGESTIONS FOR REFINEMENT USING A MUMMICHOG (FUNDULUS HETEROCLITUS) CASE STUDY  Academic Article
• CIHR Candrive Cohort Comparison with Canadian Household Population Holding Valid Driver’s Licenses  Academic Article
• Central coordination as an alternative for local coordination in a multicenter randomized controlled trial: the FAITH trial experience  Academic Article
• Cervical spine findings on MRI in people with neck pain compared with pain‐free controls: A systematic review and meta‐analysis  Academic Article
• Characterizing systematic challenges in sample size determination for sepsis trials  Academic Article
• Chronic Conditions and Disabilities Among Seniors  Academic Article
• Clinical decision making and the expected value of information  Academic Article
• Cochrane in CORR®: Strategies to Improve Recruitment to Randomised Trials  Academic Article
• Commentary #1  Academic Article
• Common errors in the design of orthopaedic trials: Has anything changed?  Academic Article
• Comparative responsiveness of generic and specific quality-of-life instruments  Academic Article
• Comparing dedicated and designated models of integrating mental health into chronic disease care: study protocol for a cluster randomized controlled trial  Academic Article
• Comparison of Arthroplasty Trial Publications After Registration in ClinicalTrials.gov  Academic Article
• Comparison of Preprint Postings of Randomized Clinical Trials on COVID-19 and Corresponding Published Journal Articles  Academic Article
• Comparison of fentanyl and sufentanil as adjuncts to bupivacaine for labor epidural analgesia  Academic Article
• Complex procedural skills are retained for a minimum of 1 yr after a single high-fidelity simulation training session  Academic Article
• Conducting EQ-5D Valuation Studies in Resource-Constrained Countries: The Potential Use of Shrinkage Estimators to Reduce Sample Size  Academic Article
• Confidence interval of risk difference by different statistical methods and its impact on the study conclusion in antibiotic non-inferiority trials  Academic Article
• Confidence intervals for cost-effectiveness ratios: An application of Fieller's theorem  Academic Article
• Confidence intervals for intraclass correlation coefficients in variance components models  Academic Article
• Conflict of interest is not associated with positive conclusions in toothpaste trials: a systematic survey  Academic Article
• Continued stabilization of trabecular metal tibial monoblock total knee arthroplasty components at 5 years—measured with radiostereometric analysis  Academic Article
• Correction: Reported Methodologic Quality and Discrepancies between Large and Small Randomized Trials in Meta-Analyses  Academic Article
• Correlation of single arm versus randomised phase 2 oncology trial characteristics with phase 3 outcome  Academic Article
• Cost-effective recruitment methods for a large randomised trial in people with diabetes: A Study of Cardiovascular Events iN Diabetes (ASCEND)  Academic Article
• Current State of Evidence on Kidney Transplantation: How Fragile Are the Results?  Academic Article
• Dabigatran following acute transient ischemic attack and minor stroke II (DATAS II)  Academic Article
• Decomposition-enhanced spike-triggered averaging: Contraction level effects  Academic Article
• Design and analysis of factorial clinical trials: The impact of one treatment's effectiveness on the statistical power and required sample size of the other  Academic Article
• Design and analysis of studies evaluating smoking cessation interventions where effects vary between practices or practitioners  Academic Article
• Design and methods of the MAINTAIN study: A randomized controlled clinical trial of micronutrient and antioxidant supplementation in untreated HIV infection  Academic Article
• Design, analysis, and presentation of crossover trials  Academic Article
• Determining optimal sample sizes for multi-stage randomized clinical trials using value of information methods  Academic Article
• Determining optimal sample sizes for multistage adaptive randomized clinical trials from an industry perspective using value of information methods  Academic Article
• Determining the sample size in a clinical trial  Academic Article
• Development of the IRIS-AR strategy: an intervention to improve rates of accrual and retention for the VTE-PRO randomized controlled trial  Academic Article
• Different meta-analysis methods can change judgements about imprecision of effect estimates: a meta-epidemiological study  Academic Article
• Digital palpation of endotracheal tube tip as a method of confirming endotracheal tube position in neonates: an open-label, three-armed randomized controlled trial  Academic Article
• Early invasive compared with a selective invasive strategy in women with non-ST-elevation acute coronary syndromes: a substudy of the OASIS 5 trial and a meta-analysis of previous randomized trials  Academic Article
• Edoxaban for treatment of venous thromboembolism in patients with cancer  Academic Article
• Effect of 7 days of exercise on exogenous carbohydrate oxidation and insulin resistance in children with obesity  Academic Article
• Effect of continuous versus dichotomous outcome variables on study power when sample sizes of orthopaedic randomized trials are small  Academic Article
• Effect sizes can be calculated for studies reporting ranges for outcome variables in systematic reviews  Academic Article
• Effectiveness and cost-effectiveness of cognitive adaptation training as a nursing intervention in long-term residential patients with severe mental illness: study protocol for a randomized controlled trial  Academic Article
• Effectiveness of pharmaceutical care at discharge in the emergency department: study protocol of a randomized controlled trial  Academic Article
• Effects of Sample Size on Estimates of Population Growth Rates Calculated with Matrix Models  Academic Article
• Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial  Academic Article
• Efficacy of ultra-micronized palmitoylethanolamide (um-PEA) in geriatric patients with chronic pain: study protocol for a series of N-of-1 randomized trials  Academic Article
• Emerging Trends in Clinical Trial Design  Academic Article
• Establishment of micromethods for macronutrient contents analysis in breast milk  Academic Article
• Estimating required information size by quantifying diversity in random-effects model meta-analyses  Academic Article
• Estimating the number needed to treat (NNT) index when the data are subject to error  Academic Article
• Estimation, Power and Sample Size Calculations for Stochastic Cost and Effectiveness Analysis  Academic Article
• Ethnic Group Differences in Bullying Perpetration: A Meta‐Analysis  Academic Article
• Evaluating Agreement: Conducting a Reliability Study  Academic Article
• FIT for FUNCTION: study protocol for a randomized controlled trial  Academic Article
• Family impact of child oral and oro-facial conditions  Academic Article
• Faà di Bruno’s formula and the distributions of random partitions in population genetics and physics  Conference Paper
• Forced Euvolemic Diuresis With Mannitol and Furosemide for Prevention of Contrast-Induced Nephropathy in Patients With CKD Undergoing Coronary Angiography: A Randomized Controlled Trial  Academic Article
• Fragility of Results in Ophthalmology Randomized Controlled Trials  Academic Article
• Fragility of clinical trials across research fields: A synthesis of methodological reviews  Academic Article
• Fragility of results from randomized controlled trials supporting the guidelines for the treatment of osteoporosis: a retrospective analysis  Academic Article
• Fragility of statistically significant findings from randomized trials in comparing laparoscopic versus robotic abdominopelvic surgeries  Academic Article
• Fragility of statistically significant outcomes in randomized trials comparing bariatric surgeries  Academic Article
• From the Corrections Officer: Why We Correct for Multiple Tests  Academic Article
• GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach  Academic Article
• GRADE Leitlinien: 5. Einschätzung der Qualität der Evidenz – Publikationsbias  Academic Article
• GRADE Leitlinien: 6. Einschätzung der Qualität der Evidenz – Unzureichende Präzision  Academic Article
• GRADE guidelines 6. Rating the quality of evidence—imprecision  Academic Article
• GRADE guidelines: 7. Rating the quality of evidence—inconsistency  Academic Article
• Global Discrepancies in the Diagnosis, Surgical Management, and Investigation of Femoroacetabular Impingement  Academic Article
• Globally optimal trial design for local decision making  Academic Article
• Goodbye, number needed to treat?  Academic Article
• Health years equivalents as a measurement of preferences for dental interventions.  Academic Article
• How many, precisely?  Academic Article
• Identifying trial recruitment uncertainties using a James Lind Alliance Priority Setting Partnership – the PRioRiTy (Prioritising Recruitment in Randomised Trials) study  Academic Article
• Implementing evidence-based recommended practices for the management of patients with mild traumatic brain injuries in Australian emergency care departments: study protocol for a cluster randomised controlled trial  Academic Article
• In the Era of Systematic Reviews, Does the Size of an Individual Trial Still Matter?  Academic Article
• Integrating Mortality and Morbidity Outcomes  Academic Article
• Interval estimation and optimal design for the within-subject coefficient of variation for continuous and binary variables  Academic Article
• Intrauterine resuscitation during the second stage of term labour by maternal hyperoxygenation versus conventional care: study protocol for a randomised controlled trial (INTEREST O2)  Academic Article
• Is NNT now the number needed to traumatize?  Academic Article
• Is There Really a Power Shortage in Clinical Trials Testing the “Homocysteine Hypothesis?”  Academic Article
• Is there a role for anterior zone sampling as part of saturation trans-rectal ultrasound guided prostate biopsy?  Academic Article
• Issues in the planning and conduct of randomised trials  Academic Article
• Justifying the number of animals for each experiment  Academic Article
• Kidney Function Endpoints in Kidney Transplant Trials: A Struggle for Power  Academic Article
• LOST to follow-up Information in Trials (LOST-IT): a protocol on the potential impact  Academic Article
• Lateral Extra-articular Tenodesis Reduces Rotational Laxity When Combined With Anterior Cruciate Ligament Reconstruction: A Systematic Review of the Literature  Academic Article
• Likert scales, levels of measurement and the “laws” of statistics  Academic Article
• Lossy-to-lossless compression of medical volumetric data using three-dimensional integer wavelet transforms  Academic Article
• L’observance incomplète de l’algorithme de prise en charge de l’intubation difficile de l’ASA demeure inchangée au terme d’une séance de simulation haute fidélité  Academic Article
• MRI in the diagnosis of pediatric multiple sclerosis  Academic Article
• Meta-analysis of randomized trials: Looking back and looking ahead  Academic Article
• Methodological and reporting quality of non-inferiority randomized controlled trials comparing antifungal therapies: a systematic review  Academic Article
• Methodological design for economic evaluation in Public Access Defibrillation (PAD) trial  Academic Article
• Methodological issues in infertility research  Academic Article
• Methodological survey of designed uneven randomization trials (DU-RANDOM): a protocol  Academic Article
• Methods for confidence interval estimation of a ratio parameter with application to location quotients  Academic Article
• Modelling heterogeneity variances in multiple treatment comparison meta-analysis – Are informative priors the better solution?  Academic Article
• Morphometric Analysis of Mouse Airways After Chronic Allergen Challenge  Academic Article
• Multimorbidity risk assessment in adolescents and adults with cerebral palsy: a protocol for establishing a core outcome set for clinical research and practice  Academic Article
• N of 1 randomized trials: a commentary  Academic Article
• New methods can extend the use of minimal important difference units in meta-analyses of continuous outcome measures  Academic Article
• No Difference in Superiority Trial Does Not Equate Noninferiority  Academic Article
• Non-surgical management of stress urinary incontinence: ambulatory treatments for leakage associated with stress (ATLAS) trial  Academic Article
• North American Vasovagal Pacemaker Study: Study Design and Organization  Academic Article
• Number needed to treat (NNT): estimation of a measure of clinical benefit  Academic Article
• Optimal Context Quantization in Lossless Compression of Image Data Sequences  Academic Article
• Optimal clinical trial design using value of information methods with imperfect implementation  Academic Article
• Optimal sample size determinations from an industry perspective based on the expected value of information  Academic Article
• Optimising the two‐stage randomised trial design when some participants are indifferent in their treatment preferences  Academic Article
• Optimized sampling patterns for multidimensional T2 experiments  Academic Article
• Outcome Measures and Implications for Sample-Size Calculations  Academic Article
• Overcoming the limitations of current meta-analysis of randomised controlled trials  Academic Article
• Patient reported outcome measures in clinical trials should be initially analyzed as continuous outcomes for statistical significance and responder analyses should be reserved as secondary analyses  Academic Article
• Patients undergoing knee surgery provided accurate ratings of preoperative quality of life and function 2 weeks after surgery  Academic Article
• Patients with aortic stenosis: Cardiac complications in non-cardiac surgery  Academic Article
• Physician Pain Reminder as an Intervention to Enhance Analgesia for Extremity and Clavicle Injuries in Pediatric Emergency  Academic Article
• Pitfalls in the design and analysis of efficacy trials in subfertility: Associate editor's commentary: on the article 'Common statistical errors in the design and analysis of subfertility trials' by A.Vail and E.Gardner.  Academic Article
• Pneumococcal Vaccination and Cardiovascular Events in Men  Academic Article
• Poor quality patient reported outcome measures bias effect estimates in orthopaedic randomized studies  Academic Article
• Practical Research Methods for Orthopaedic Surgeons  Academic Article
• Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA2 five-stage study, including a workshop  Academic Article
• Prediction of RECRUITment In randomized clinical Trials (RECRUIT-IT)—rationale and design for an international collaborative study  Academic Article
• Predictors of Increased Fragility Index Scores in Surgical Randomized Controlled Trials: An Umbrella Review  Academic Article
• Preparing a research protocol to improve chances for success  Academic Article
• Promoting deceased organ and tissue donation registration in family physician waiting rooms (RegisterNow-1 trial): study protocol for a pragmatic, stepped-wedge, cluster randomized controlled registry  Academic Article
• Prophylactic Diclectin® reduces the incidence of postoperative vomiting  Academic Article
• Pros and Cons of Composite Endpoints in Anesthesia Trials  Academic Article
• Protocol for a randomised controlled trial to evaluate the effectiveness of improving tuberculosis patients’ treatment adherence via electronic monitors and an app versus usual care in Tibet  Academic Article
• Quality of life and long-term outcomes after hospitalization for COVID-19: Protocol for a prospective cohort study (Coalition VII).  Academic Article
• Quality of randomized clinical trials in juvenile idiopathic arthritis  Academic Article
• Quantitative evaluation of single-arm versus randomized phase II cancer clinical trials  Academic Article
• Random error in cardiovascular meta-analyses: How common are false positive and false negative results?  Academic Article
• Randomised trials with provision for early stopping for benefit (or harm): The impact on the estimated treatment effect  Academic Article
• Randomized controlled trials in non-pharmacological rehabilitation research: a scoping review of the reporting of sample size calculation, randomization procedure, and statistical analyses  Academic Article
• Randomized trials published in higher vs. lower impact journals differ in design, conduct, and analysis  Academic Article
• Randomizing patients by family practice: sample size estimation, intracluster correlation and data analysis  Academic Article
• Rapid recovery of life at ground zero of the end-Cretaceous mass extinction  Academic Article
• Rationale and design of a study assessing treatment strategies of atrial fibrillation in patients with heart failure: The Atrial Fibrillation and Congestive Heart Failure (AF-CHF) trial  Academic Article
• Rationale and methods of an Evaluation of the Effectiveness of the Community Paramedicine at Home (CP@home) program for frequent users of emergency medical services in multiple Ontario regions: a study protocol for a randomized controlled trial  Academic Article
• Recommendations for reporting the results of studies of instrument and scale development and testing  Academic Article
• Reporting of primary outcome measures and sample size calculations in randomized controlled trials in dermatology journals  Academic Article
• Resolving methodological and clinical issues in the design of efficacy trials in assisted reproductive technologies: a mini-review  Academic Article
• Results of the First Pilot Randomized Controlled Trial of Fecal Microbiota Transplant In Pediatric Ulcerative Colitis: Lessons, Limitations, and Future Prospects  Academic Article
• Revisiting Sample Size: Are Big Trials the Answer?  Academic Article
• Roland-Morris Scale Reliability  Academic Article
• SAMURAI: Sensitivity analysis of a meta-analysis with unpublished but registered analytical investigations (software)  Academic Article
• Sample Size Determination for Cost-Effectiveness Trials  Academic Article
• Sample Size and Power When Designing a Randomized Trial for the Estimation of Treatment, Selection, and Preference Effects  Academic Article
• Sample Size in Clinical Research: When is Enough Enough?  Academic Article
• Sample size and optimal designs for reliability studies  Academic Article
• Sample size and power considerations in network meta-analysis  Academic Article
• Sample size and power issues in estimating incremental cost-effectiveness ratios from clinical trials data  Academic Article
• Sample size calculations and methacholine challenge tests  Academic Article
• Sample size calculations for educational interventions: principles and methods  Academic Article
• Sample size calculations: should the emperor's clothes be off the peg or made to measure?  Academic Article
• Sample size determination for bibliographic retrieval studies  Academic Article
• Sample sizes for clinical trials using sputum eosinophils as a primary outcome  Academic Article
• Sample sizes, scoops and educational science  Academic Article
• Selecting participants that raise a clinical trial’s population attributable fraction can increase the treatment effect within the trial and reduce the required sample size  Academic Article
• Sensible guidelines for the conduct of large randomized trials  Academic Article
• Simple randomization did not protect against bias in smaller trials  Academic Article
• Sparse Canonical Correlation Analysis with Application to Genomic Data Integration  Academic Article
• Spatial scaling factors explain eccentricity effects on face ERPs  Academic Article
• Statistical methods for unidirectional switch designs: Past, present, and future  Academic Article
• Statistics Commentary Series  Academic Article
• Statistics Commentary Series  Academic Article
• Strategic use of new generation antidepressants for depression: SUN(^_^) D protocol update and statistical analysis plan  Academic Article
• Subgroup Analysis of Trials Is Rarely Easy (SATIRE): a study protocol for a systematic review to characterize the analysis, reporting, and claim of subgroup effects in randomized trials  Academic Article
• Surgery in Patients with Super Obesity: Medium‐Term Follow‐Up Outcomes at a High‐Volume Center  Academic Article
• Survival distributions impact the power of randomized placebo-phase design and parallel groups randomized clinical trials  Academic Article
• TEACH: Trial of Education And Compliance in Heart dysfunction chronic disease and heart failure (HF) as an increasing problem  Academic Article
• Testing against “normal” with environmental data  Academic Article
• The Complexity of Conducting a Multicenter Clinical Trial: Taking It to the Next Level Stipulated by the Federal Agencies  Academic Article
• The Defibrillator in Acute Myocardial Infarction Trial (DINAMIT): Study protocol  Academic Article
• The Fragility of Statistically Significant Findings From Randomized Controlled Trials in Hip and Knee Arthroplasty  Academic Article
• The Fragility of Statistically Significant Findings From Randomized Trials in Sports Surgery: A Systematic Survey  Academic Article
• The Fragility of Statistically Significant Randomized Controlled Trials in Plastic Surgery  Conference Paper
• The Fragility of Statistically Significant Results in Gynaecologic Surgery: A Systematic Review  Academic Article
• The HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol  Academic Article
• The Inhaled Steroid Treatment as Regular Therapy in Early Asthma (START) Study  Academic Article
• The International Quotidian Dialysis Registry: Annual report 2005  Academic Article
• The Intracerebral Haemorrhage Acutely Decreasing Arterial Pressure Trial: ICH ADAPT  Academic Article
• The Need for Large Clinical Studies in Perioperative Medicine  Academic Article
• The Number of Patients and Events Required to Limit the Risk of Overestimation of Intervention Effects in Meta-Analysis—A Simulation Study  Academic Article
• The Relation Between the Minimally Important Difference and Patient Benefit  Academic Article
• The SYGMA programme of phase 3 trials to evaluate the efficacy and safety of budesonide/formoterol given ‘as needed’ in mild asthma: study protocols for two randomised controlled trials  Academic Article
• The Tactics of Large Randomized Trials  Academic Article
• The assessment of lifestyle changes during the COVID-19 pandemic using a multidimensional scale  Academic Article
• The association between Helicobacter pylori infection and adult height  Academic Article
• The choice of the noninferiority margin in clinical trials was driven by baseline risk, type of primary outcome, and benefits of new treatment  Academic Article
• The fragility of significant results from randomized controlled trials in esophageal surgeries  Academic Article
• The fragility of statistically significant findings from randomized controlled trials in pediatric appendicitis: A systematic review  Academic Article
• The fragility of trial results involves more than statistical significance alone  Academic Article
• The incidence of dementia in Canada  Academic Article
• The long-term impact of treatment with electroconvulsive therapy on discrete memory systems in patients with bipolar disorder.  Academic Article
• The number needed to treat (NNT) can be adjusted for bias when the outcome is measured with error  Academic Article
• The number needed to treat for net effect (NNTnet) as a metric for measuring combined benefits and harms  Academic Article
• The rationale and design of the Beta-blocker to LOwer CArdiovascular Dialysis Events (BLOCADE) Feasibility Study  Academic Article
• The reproducibility and sample size requirements of exercise-induced bronchoconstriction measurements  Academic Article
• The role of randomized cluster crossover trials for comparative effectiveness testing in anesthesia: design of the Benzodiazepine-Free Cardiac Anesthesia for Reduction in Postoperative Delirium (B-Free) trial  Academic Article
• The statistical significance of randomized controlled trial results is frequently fragile: a case for a Fragility Index  Academic Article
• The unclear zone in phase II clinical trials  Academic Article
• The value of information and optimal clinical trial design  Academic Article
• The ‘goddess of randomisation’ in small samples  Academic Article
• Thinking Small: Research Designs Appropriate for Clinical Practice  Academic Article
• Time and Expected Value of Sample Information Wait for No Patient  Academic Article
• Trends in the application of dynamic allocation methods in multi-arm cancer clinical trials  Academic Article
• Trial sample size, but not trial quality, is associated with positive study outcome  Academic Article
• Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis  Academic Article
• Trial sequential analysis reveals insufficient information size and potentially false positive results in many meta-analyses  Academic Article
• Twenty-year trends in racial and ethnic enrollment in large diabetes randomized controlled trials  Academic Article
• Type-II Error Rates (Beta Errors) of Randomized Trials in Orthopaedic Trauma  Academic Article
• Unified approach to optimal estimation of mean and standard deviation from sample summaries  Academic Article
• Using the ratio of means as the effect size measure in combining results of microarray experiments  Academic Article
• Validation of a refined short-term adult fish reproductive test with improved power for mummichog (Fundulus heteroclitus) to test complex effluents  Academic Article
• Value of information methods for planning and analyzing clinical studies optimize decision making and research planning  Academic Article
• Variations in stepped-wedge cluster randomized trial design: Insights from the Patient-Centered Care Transitions in Heart Failure trial  Academic Article
• What are we confident about?  Academic Article
• What differences are detected by superiority trials or ruled out by noninferiority trials? A cross-sectional study on a random sample of two-hundred two-arms parallel group randomized clinical trials  Academic Article
• When should one adjust for measurement error in baseline variables in observational studies?  Academic Article
• Which cancer clinical trials should be considered for economic evaluation? Selection criteria from the National Cancer Institute of Canada's Working Group on Economic Analysis.  Academic Article
• Why perform a priori sample size calculation?  Academic Article
• Why we permute blocks?  Academic Article
• XANTUS: rationale and design of a noninterventional study of rivaroxaban for the prevention of stroke in patients with atrial fibrillation  Academic Article