Journal article
Are large simple trials for dementia prevention possible?
Abstract
New trials of dementia prevention are needed to test novel strategies and agents. Large, simple, cardiovascular trials have successfully discovered treatments with moderate but worthwhile effects to prevent heart attack and stroke. The design of these trials may hold lessons for the dementia prevention. Here we outline suitable populations, interventions and outcomes for large simple trials in dementia prevention. We consider what features are …
Authors
Whiteley WN; Anand S; Bangdiwala SI; Bosch J; Canavan M; Chertkow H; Gerstein HC; Gorelick P; O’Donnell M; Paré G
Journal
Age and Ageing, Vol. 49, No. 2, pp. 154–160
Publisher
Oxford University Press (OUP)
Publication Date
February 27, 2020
DOI
10.1093/ageing/afz152
ISSN
0002-0729