Journal article
Meta-analysis of randomized trials: Looking back and looking ahead
Abstract
Meta-analyses as currently practiced are usually retrospective. They can be made more rigorous by developing a protocol that incorporates prospectively the elements that are usually necessary in a well-designed trial. Meta-analysis and large trials are complementary. Meta-analysis of small trials is useful in generating the hypotheses and assisting in the design of the large trials that are needed. Once the large trials have been completed, …
Authors
Yusuf S
Journal
Contemporary Clinical Trials, Vol. 18, No. 6, pp. 594–601
Publisher
Elsevier
Publication Date
12 1997
DOI
10.1016/s0197-2456(97)00052-4
ISSN
1551-7144