Journal article
The unclear zone in phase II clinical trials
Abstract
OBJECTIVE: There appears to be considerable confusion about the interpretation of phase II clinical trial conclusions as contrasted with the alternative (HA) and null (H0) hypotheses. This study was conducted to evaluate whether there is congruence with numerical results of phase II trials and their overall verbal conclusions.
METHODS: A literature search of 2006 and 2007 phase II clinical trials was conducted. The alternative and null …
Authors
Allegro S; Pond GR; Hotte SJ
Journal
European Journal of Cancer, Vol. 46, No. 13, pp. 2408–2413
Publisher
Elsevier
Publication Date
September 2010
DOI
10.1016/j.ejca.2010.05.027
ISSN
0959-8049