Journal article
Fragility of results from randomized controlled trials supporting the guidelines for the treatment of osteoporosis: a retrospective analysis
Abstract
This is the first report on the fragility of results from randomized controlled trials (RCTs) for the treatment of osteoporosis. The results of aforementioned RCTs appear to depend on a small number of events and are generally statistically fragile.IntroductionOsteoporosis remains a health concern worldwide. Evidence-based guideline recommendations that are mainly based on results of clinical trials are important to clinical decision-making. …
Authors
Huang X; Chen B; Thabane L; Adachi JD; Li G
Journal
Osteoporosis International, Vol. 32, No. 9, pp. 1713–1723
Publisher
Springer Nature
Publication Date
September 2021
DOI
10.1007/s00198-021-05865-y
ISSN
0937-941X