Journal article
An opportunity cost approach to sample size calculation in cost‐effectiveness analysis
Abstract
The inclusion of economic evaluations as part of clinical trials has led to concerns about the adequacy of trial sample size to support such analysis. The analytical tool of cost-effectiveness analysis is the incremental cost-effectiveness ratio (ICER), which is compared with a threshold value (lambda) as a method to determine the efficiency of a health-care intervention. Accordingly, many of the methods suggested to calculating the sample size …
Authors
Gafni A; Walter SD; Birch S; Sendi P
Journal
Health Economics, Vol. 17, No. 1, pp. 99–107
Publisher
Wiley
Publication Date
January 2008
DOI
10.1002/hec.1244
ISSN
1057-9230