Journal article
Sample Size and Power When Designing a Randomized Trial for the Estimation of Treatment, Selection, and Preference Effects
Abstract
BACKGROUND: A 2-stage randomized trial design, incorporating participant choice, provides unbiased estimates of the effects of the treatment or intervention (treatment effect), the difference between outcomes for participants who prefer one treatment compared with another (selection effect), and the interaction between participants' preferences for treatment and the treatment actually received (preference effect). It is important to ensure that …
Authors
Turner RM; Walter SD; Macaskill P; McCaffery KJ; Irwig L
Journal
Medical Decision Making, Vol. 34, No. 6, pp. 711–719
Publisher
SAGE Publications
Publication Date
August 2014
DOI
10.1177/0272989x14525264
ISSN
0272-989X