selected scholarly activity
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chapters
- Impact of prostate cancer stem cell niches on prostate cancer tumorigenesis and progression. 177-204. 2021
- Chapter 22 Downregulation of the Raf kinase inhibitory protein (RKIP) in clear cell renal cell carcinoma associates with poor prognosis. 435-457. 2020
- Downregulation of the Raf kinase inhibitory protein (RKIP) in clear cell renal cell carcinoma associates with poor prognosis. 435-457. 2020
- Cyclin-dependent kinase 5 (Cdk5) and neuron-specific Cdk5 activators. Progress in cell cycle research. 205-216. 1996
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conferences
- Abstract 1621: Contactin 1 (CNTN1) promotes prostate cancer tumorigenesis in transgenic models. Cancer Research. 1621-1621. 2020
- Assessing interrater variation with funnel plots in 2,190 prostate biopsies. Virchows Archiv. S27-S27. 2017
- Abstract P4-22-19: Time on treatment of everolimus versus endocrine monotherapy or chemotherapy for early-line treatment of HR+/HER2- metastatic breast cancer: A retrospective chart review study in the US. Cancer Research. 2017
- 168 DEFINING CONDITIONS TO GENERATE AND MAINTAIN PROSTATE CANCER STEM CELLS. Investigative Urology. E70-E71. 2011
- Methylation of Retinoic Acid Receptor, Beta (RARB) Gene Increases Risk for Prostate Cancer in African-American Men. Cancer Epidemiology, Biomarkers and Prevention. 718-718. 2011
- Neighborhood Socio-Economic Status and Individual Smoking Status Interact to Predict PAH-DNA Adduct Levels in Prostate Tissue. Cancer Epidemiology, Biomarkers and Prevention. 897-898. 2010
- Polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts. in prostate cancer. Genetic Epidemiology. 492-492. 2007
- Stretch-induced Raf-1 activation in mesangial cells requires focal adhesion-cytoskeletal integrity.. Journal of the American Society of Nephrology. 336A-336A. 2003
- NAT2 interactions on breast cancer risk: SULT1A1 and cooked meat.. Breast Cancer Research and Treatment. S153-S153. 2002
- Stretch-induced MAPK activation in mesangial cells requires Rho-mediated cytoskeletal reorganization.. Journal of the American Society of Nephrology. 87A-87A. 2002
- Gene expression in human prostate carcinoma treated with heat shock and radiation. Cell Stress and Chaperones. 499-499. 2000
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journal articles
- IQGAP3 is relevant to prostate cancer: A detailed presentation of potential pathomechanisms. Journal of Advanced Research. 54:195-210. 2023
- Taxifolin Inhibits the Growth of Non-Small-Cell Lung Cancer via Downregulating Genes Displaying Novel and Robust Associations with Immune Evasion Factors. Cancers. 15:4818-4818. 2023
- HSD17B6 delays type 2 diabetes development via inhibiting SREBP activation. Metabolism: Clinical and Experimental. 145:155631-155631. 2023
- Peroxiredoxin 1 aggravates acute kidney injury by promoting inflammation through Mincle/Syk/NF-κB signaling. Kidney International. 104:305-323. 2023
- Taxifolin Inhibits Breast Cancer Growth by Facilitating CD8+ T Cell Infiltration and Inducing a Novel Set of Genes including Potential Tumor Suppressor Genes in 1q21.3. Cancers. 15:3203-3203. 2023
- PCSK9 facilitates melanoma pathogenesis via a network regulating tumor immunity. Journal of Experimental and Clinical Cancer Research. 42:2. 2023
- Prediction of Adrenocortical Carcinoma Relapse and Prognosis with a Set of Novel Multigene Panels. Cancers. 14:2805-2805. 2022
- Insights of RKIP-Derived Suppression of Prostate Cancer. Cancers. 13:6388-6388. 2021
- Prognostic and Therapeutic Potential of the OIP5 Network in Papillary Renal Cell Carcinoma. Cancers. 13:4483-4483. 2021
- Mechanisms of Primary Membranous Nephropathy. Biomolecules. 11:513-513. 2021
- Differential Expression of a Panel of Ten CNTN1-Associated Genes during Prostate Cancer Progression and the Predictive Properties of the Panel towards Prostate Cancer Relapse. Genes. 12:257-257. 2021
- Effective Prediction of Prostate Cancer Recurrence through the IQGAP1 Network. Cancers. 13:430-430. 2021
- Construction of a Novel Multigene Panel Potently Predicting Poor Prognosis in Patients with Clear Cell Renal Cell Carcinoma. Cancers. 12:3471-3471. 2020
- Contactin 1: An Important and Emerging Oncogenic Protein Promoting Cancer Progression and Metastasis. Genes. 11:874-874. 2020
- Chronic Inflammatory Demyelinating Polyneuropathy and Concurrent Membranous Nephropathy. Canadian Journal of Neurological Sciences. 47:585-587. 2020
- The Oncogenic Potential of the Centromeric Border Protein FAM84B of the 8q24.21 Gene Desert. Genes. 11:312-312. 2020
- Contributions of DNA Damage to Alzheimer’s Disease. International Journal of Molecular Sciences. 21:1666-1666. 2020
- Oxidative stress contributes to vascular calcification in patients with chronic kidney disease. Journal of Molecular and Cellular Cardiology. 138:256-268. 2020
- Assessment of biochemical recurrence of prostate cancer (Review). International Journal of Oncology. 55:1194-1212. 2019
- The Central Contributions of Breast Cancer Stem Cells in Developing Resistance to Endocrine Therapy in Estrogen Receptor (ER)-Positive Breast Cancer. Cancers. 11:1028-1028. 2019
- Circulating Peroxiredoxin-1 is a novel damage-associated molecular pattern and aggravates acute liver injury via promoting inflammation. Free Radical Biology and Medicine. 137:24-36. 2019
- Downregulation of CYB5D2 is associated with breast cancer progression. Scientific Reports. 9:6624. 2019
- The Contributions of Prostate Cancer Stem Cells in Prostate Cancer Initiation and Metastasis. Cancers. 11:434-434. 2019
- FAM84B promotes prostate tumorigenesis through a network alteration. Therapeutic Advances in Medical Oncology. 11:175883591984637-175883591984637. 2019
- The TGFβ-ERK pathway contributes to Notch3 upregulation in the renal tubular epithelial cells of patients with obstructive nephropathy. Cellular Signalling. 51:139-151. 2018
- Construction of a set of novel and robust gene expression signatures predicting prostate cancer recurrence. Molecular Oncology. 12:1559-1578. 2018
- Biphasic Alteration of Butyrylcholinesterase (BChE) During Prostate Cancer Development. Translational Oncology. 11:1012-1022. 2018
- Polycomb complex protein BMI1 confers resistance to tamoxifen in estrogen receptor positive breast cancer. Cancer Letters. 426:4-13. 2018
- Etoposide-induced DNA damage affects multiple cellular pathways in addition to DNA damage response. Oncotarget. 9:24122-24139. 2018
- A role of SIPL1/SHARPIN in promoting resistance to hormone therapy in breast cancer. Biochimica et Biophysica Acta - Molecular Basis of Disease. 1864:735-745. 2018
- Signatures derived from increase in SHARPIN gene copy number are associated with poor prognosis in patients with breast cancer. BBA Clinical. 8:56-65. 2017
- Overexpression of MUC1 and Genomic Alterations in Its Network Associate with Prostate Cancer Progression. Neoplasia. 19:857-867. 2017
- BMI1 reduces ATR activation and signalling caused by hydroxyurea. Oncotarget. 8:89707-89721. 2017
- Microvesicles Contribute to the Bystander Effect of DNA Damage. International Journal of Molecular Sciences. 18:788-788. 2017
- Upregulation of FAM84B during prostate cancer progression. Oncotarget. 8:19218-19235. 2017
- Progress towards accurate prediction of overall survival in men with metastatic castration-resistant prostate cancer. Journal of Xiangya Medicine. 2:17-17. 2017
- Next Generation Quality: Assessing the Physician in Clinical History Completeness and Diagnostic Interpretations Using Funnel Plots and Normalized Deviations Plots in 3,854 Prostate Biopsies. Journal of Pathology Informatics. 8:43-43. 2017
- Amplification of MUC1 in prostate cancer metastasis and CRPC development. Oncotarget. 7:83115-83133. 2016
- CYB5D2 displays tumor suppression activities towards cervical cancer. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1862:556-565. 2016
- Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer. Cancer Research. 76:1603-1614. 2016
- Dataset on the effects of CYB5D2 on the distribution of HeLa cervical cancer cell cycle. Genomics Data. 6:811-816. 2016
- Hematoporphyrin monomethyl ether combined with He–Ne laser irradiation-induced apoptosis in canine breast cancer cells through the mitochondrial pathway. Journal of Veterinary Science. 17:235-235. 2016
- A Novel Aspect of Tumorigenesis—BMI1 Functions in Regulating DNA Damage Response. Biomolecules. 5:3396-3415. 2015
- Prostate Cancer Stem-like Cells Contribute to the Development of Castration-Resistant Prostate Cancer. Cancers. 7:2290-2308. 2015
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P eroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis. Nephrology. 20:832-842. 2015 - Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs OXPHOS and prostate cancer metastatic spread. Oncotarget. 6:24061-24074. 2015
- BMI1, ATM and DDR. Oncoscience. 2:665-666. 2015
- Factors Promoting Tamoxifen Resistance in Breast Cancer via Stimulating Breast Cancer Stem Cell Expansion. Current Medicinal Chemistry. 22:2360-2374. 2015
- BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation. Oncogene. 34:3063-3075. 2015
- Elevation of SIPL1 (SHARPIN) Increases Breast Cancer Risk. PLoS ONE. 10:e0127546-e0127546. 2015
- IQGAP2 Displays Tumor Suppression Functions. Journal of Analytical Oncology. 4:86-93. 2015
- PKM2 contributes to cancer metabolism. Cancer Letters. 356:184-191. 2015
- SIPL1-facilitated PTEN ubiquitination contributes to its association with PTEN. Cellular Signalling. 26:2749-2756. 2014
- Prostate cancer stem-like cells proliferate slowly and resist etoposide-induced cytotoxicity via enhancing DNA damage response. Experimental Cell Research. 328:132-142. 2014
- Common reduction of the Raf kinase inhibitory protein in clear cell renal cell carcinoma. Oncotarget. 5:7406-7419. 2014
- SIPL1 enhances the proliferation, attachment, and migration of CHO cells by inhibiting PTEN function. International Journal of Molecular Medicine. 34:835-841. 2014
- Changes in PKM2 Associate with Prostate Cancer Progression. Cancer Investigation. 32:330-338. 2014
- Aldehyde dehydrogenase 3A1 associates with prostate tumorigenesis. British Journal of Cancer. 110:2593-2603. 2014
- The Protein-Protein Interaction-Mediated Inactivation of PTEN. Current Molecular Medicine. 14:22-33. 2014
- Fluorofenidone Offers Improved Renoprotection at Early Interventions during the Course of Diabetic Nephropathy in db/db Mice via Multiple Pathways. PLoS ONE. 9:e111242-e111242. 2014
- ERK kinases modulate the activation of PI3 kinase related kinases (PIKKs) in DNA damage response.. Histology and Histopathology. 28:1547-1554. 2013
- Effect of hematoporphyrin monomethyl ether-mediated PDT on the mitochondria of canine breast cancer cells. Photodiagnosis and Photodynamic Therapy. 10:414-421. 2013
- SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells. Cellular Signalling. 25:2734-2742. 2013
- Clear cell renal cell carcinoma induces fibroblast-mediated production of stromal periostin. European Journal of Cancer. 49:3537-3546. 2013
- Gene Therapy, A Targeted Treatment for Diabetic Nephropathy. Current Medicinal Chemistry. 20:3774-3784. 2013
- Deficiency of TDAG51 Protects Against Atherosclerosis by Modulating Apoptosis, Cholesterol Efflux, and Peroxiredoxin‐1 Expression. Journal of the American Heart Association. 2:e000134. 2013
- Balanced translocation t(3;18)(p13;q22.3) and points mutation in the ZNF407 gene detected in patients with both moderate non-syndromic intellectual disability and autism. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1832:431-438. 2013
- Contactin-1 Reduces E-Cadherin Expression Via Activating AKT in Lung Cancer. PLoS ONE. 8:e65463-e65463. 2013
- Differential proteomic analysis of renal tissue in mesangial proliferative glomerulonephritis using iTRAQ technology. Journal of Nephrology. 26:191-198. 2013
- Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1833:90-100. 2013
- PKM2, a Central Point of Regulation in Cancer Metabolism. International Journal of Cell Biology. 2013:1-11. 2013
- Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation. PLoS ONE. 8:e61716-e61716. 2013
- Regulation of the Tumor Suppressor PTEN through Exosomes: A Diagnostic Potential for Prostate Cancer. PLoS ONE. 8:e70047-e70047. 2013
- IQGAP2, A candidate tumour suppressor of prostate tumorigenesis. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1822:875-884. 2012
- Extracellular Signal-Regulated Kinases Modulate DNA Damage Response - A Contributing Factor to Using MEK Inhibitors in Cancer Therapy. Current Medicinal Chemistry. 18:5476-5482. 2011
- Apoptosis induced by hematoporphyrin monomethyl ether combined with He–Ne laser irradiation in vitro on canine breast cancer cells. The Veterinary Journal. 188:325-330. 2011
- CYB5D2 enhances HeLa cells survival of etoposide-induced cytotoxicity. Biochemistry and Cell Biology. 89:341-350. 2011
- Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1813:683-694. 2011
- ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation. Cellular Signalling. 23:259-268. 2011
- α-Mannosidase 2C1 attenuates PTEN function in prostate cancer cells. Nature Communications. 2:307. 2011
- Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation. Cellular Signalling. 22:1783-1789. 2010
- Shank-interacting protein–like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells. Journal of Clinical Investigation. 120:2094-2108. 2010
- PTEN inhibits BMI1 function independently of its phosphatase activity. Molecular Cancer. 8:98. 2009
- Specific Reduction of Fas-Associated Protein with Death Domain (FADD) in Clear Cell Renal Cell Carcinoma. Cancer Investigation. 27:836-843. 2009
- Bmi1 promotes prostate tumorigenesis via inhibiting p16INK4A and p14ARF expression. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1782:642-648. 2008
- Interaction of p14ARF with Brca1 in cancer cell lines and primary breast cancer. Cell Biology International. 32:1302-1309. 2008
- Oncostatin M induction of eotaxin-1 expression requires the convergence of PI3′K and ERK1/2 MAPK signal transduction pathways. Cellular Signalling. 20:1142-1150. 2008
- Co-existence of high levels of the PTEN protein with enhanced Akt activation in renal cell carcinoma. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1772:1134-1142. 2007
- Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44(+)alpha 2 beta 1(+) cell population is enriched in tumor-initiating cells. (vol 67, pg 6796, 2007). Cancer Research. 67:8973-8973. 2007
- Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2. International Journal of Biochemistry and Cell Biology. 39:1843-1851. 2007
- ATM activation is accompanied with earlier stages of prostate tumorigenesis. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1763:1090-1097. 2006
- Identification of an ataxia telangiectasia-mutated protein mediated surveillance system to regulate Bcl-2 overexpression. Oncogene. 25:5601-5611. 2006
- p14ARF inhibits the growth of p53 deficient cells in a cell-specific manner. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1763:787-796. 2006
- ERK activity facilitates activation of the S-phase DNA damage checkpoint by modulating ATR function. Oncogene. 25:1153-1164. 2006
- Akt Mediates Mechanical Strain-Induced Collagen Production by Mesangial Cells. Journal of the American Society of Nephrology. 16:1661-1672. 2005
- Identification of a novel Wee1 isoform. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1729:1-9. 2005
- Stretch-induced Raf-1 activation in mesangial cells requires actin cytoskeletal integrity. Cellular Signalling. 17:311-320. 2005
- Identification of a hTid‐1 mutation which sensitizes gliomas to apoptosis. FEBS Letters. 578:323-330. 2004
- ATM activity contributes to the tumor-suppressing functions of p14ARF. Oncogene. 23:7355-7365. 2004
- Activation of mesangial cell MAPK in responseto homocysteine. Kidney International. 66:733-745. 2004
- Nitric Oxide Inhibits Stretch-Induced MAPK Activation in Mesangial Cells Through RhoA Inactivation. Journal of the American Society of Nephrology. 14:2790-2800. 2003
- TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia. Journal of Biological Chemistry. 278:30317-30327. 2003
- Developments in mitogen-induced extracellular kinase 1 inhibitors and their use in the treatment of disease. Expert Opinion on Therapeutic Patents. 12:1795-1811. 2002
- ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. (vol 277, pg 12710, 2002). Journal of Biological Chemistry. 277:21110-21110. 2002
- Apoptotic Release of Histones from Nucleosomes. Journal of Biological Chemistry. 277:12001-12008. 2002
- ERK Activation Mediates Cell Cycle Arrest and Apoptosis after DNA Damage Independently of p53. Journal of Biological Chemistry. 277:12710-12717. 2002
- Flux Through the Hexosamine Pathway Is a Determinant of Nuclear Factor κB– Dependent Promoter Activation. Diabetes. 51:1146-1156. 2002
- Akt Is Activated in Response to an Apoptotic Signal. Journal of Biological Chemistry. 276:30461-30466. 2001
- Neuronal cdc-2 like kinase in developing kindling rat hippocampus.. National Medical Journal of China. 114:248-252. 2001
- The association between glutathione S-transferase M1 genotype and polycyclic aromatic hydrocarbon-DNA adducts in breast tissue.. Cancer Epidemiology, Biomarkers and Prevention. 9:1079-1085. 2000
- The relationship between genetic damage from polycyclic aromatic hydrocarbons in breast tissue and breast cancer. Carcinogenesis. 21:1281-1289. 2000
- [Microsatellite instability in urine sediments from patients with transitional cell carcinoma of bladder and its clinical value].. Zhonghua wai ke za zhi [Chinese journal of surgery]. 38:294-296. 2000
- Caspase-8 Activation and Bid Cleavage Contribute to MCF7 Cellular Execution in a Caspase-3-dependent Manner during Staurosporine-mediated Apoptosis. Journal of Biological Chemistry. 275:9303-9307. 2000
- Cycloheximide-induced T-cell Death Is Mediated by a Fas-associated Death Domain-dependent Mechanism. Journal of Biological Chemistry. 274:7245-7252. 1999
- Identification and Structure Characterization of a Cdk Inhibitory Peptide Derived from Neuronal-specific Cdk5 Activator. Journal of Biological Chemistry. 274:7120-7127. 1999
- Cleavage of DFF-45/ICAD by Multiple Caspases Is Essential for Its Function during Apoptosis. Journal of Biological Chemistry. 273:28549-28552. 1998
- The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus. EMBO Journal. 17:3351-3362. 1998
- Phosphorylation of PITSLRE p110 Isoforms Accompanies Their Processing by Caspases during Fas-mediated Cell Death. Journal of Biological Chemistry. 273:16601-16607. 1998
- Association of Neurofilament Proteins with Neuronal Cdk5 Activator. Journal of Biological Chemistry. 273:2329-2335. 1998
- Changes in the expression of novel Cdk5 activator messenger RNA (p39nck5ai mRNA) during rat brain development. Neuroscience Research. 28:355-360. 1997
- Cyclin-dependent Kinase 5 (Cdk5) Activation Domain of Neuronal Cdk5 Activator. Journal of Biological Chemistry. 272:12318-12327. 1997
- Neuronal Cdc2-like kinase: from cell cycle to neuronal function. Biochemistry and Cell Biology. 74:419-429. 1996
- Cyclin-dependent kinase 5 (Cdk5) and neuron-specific Cdk5 activators. Progress in cell cycle research. 2:205-216. 1996
- Interaction of Cyclin-dependent Kinase 5 (Cdk5) and Neuronal Cdk5 Activator in Bovine Brain. Journal of Biological Chemistry. 271:1538-1543. 1996
- An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator. Journal of Biological Chemistry. 270:26897-26903. 1995
- Regulatory properties of neuronal cdc2-like kinase. Molecular and Cellular Biochemistry. 149-150:35-39. 1995
- Binding of reovirus to receptor leads to conformational changes in viral capsid proteins that are reversible upon virus detachment.. Journal of Biological Chemistry. 269:17043-17047. 1994
- Evidence That the Epidermal Growth Factor Receptor on Host Cells Confers Reovirus Infection Efficiency. Virology. 197:405-411. 1993
- Recognition of the Epidermal Growth Factor Receptor by Reovirus. Virology. 197:412-414. 1993