Journal article
Specific Reduction of Fas-Associated Protein with Death Domain (FADD) in Clear Cell Renal Cell Carcinoma
Abstract
Fas-associated protein with death domain (FADD) plays a major role in the execution of apoptosis. Attenuation of apoptosis is a hallmark of cancer. Through systemic examination of FADD in renal cell carcinoma (RCC) and adjacent nontumor kidney tissues from 85 patients, we demonstrated a significant reduction of FADD in clear cell RCC (ccRCC) compared to the respective nontumor kidney tissues. In human kidney, FADD is expressed in both the …
Authors
Xu H; He L; Feng X; Kapoor A; Tang D
Journal
Cancer Investigation, Vol. 27, No. 8, pp. 836–843
Publisher
Taylor & Francis
Publication Date
1 2009
DOI
10.1080/07357900902849681
ISSN
0735-7907