Journal article
Biphasic Alteration of Butyrylcholinesterase (BChE) During Prostate Cancer Development
Abstract
Butyrylcholinesterase (BChE) is a plasma enzyme that hydrolyzes ghrelin and bioactive esters, suggesting a role in modulating metabolism. Serum BChE is reduced in cancer patients. In prostate cancer (PC), the down-regulation is associated with disease recurrence. Nonetheless, how BChE is expressed in PC and its impact on PC remain unclear. We report here the biphasic changes of BChE expression in PC. In vitro, BChE expression was decreased in …
Authors
Gu Y; Chow MJ; Kapoor A; Mei W; Jiang Y; Yan J; De Melo J; Seliman M; Yang H; Cutz J-C
Journal
Translational Oncology, Vol. 11, No. 4, pp. 1012–1022
Publisher
Elsevier
Publication Date
August 2018
DOI
10.1016/j.tranon.2018.06.003
ISSN
1944-7124