Neuronal cdc-2 like kinase in developing kindling rat hippocampus.

Abstract

OBJECTIVE: To test the hypothesis that neuronal cdc2-like kinase (Cdk5/p35nck5a) plays an important role in neuronal maturation and sprouting. METHODS: Changes kinase activity, expression levels and subcellular localizations of Cdk5 and p35nck5a in the rat hippocampus were studied during kindling progression by Western blot analysis, immunohistochemistry, immunoprecipitation and kinase assay.

Authors

Cai X; Tang D; Xu R

Journal

Chinese Medical Journal, Vol. 114, No. 3, pp. 248–252

Publication Date

3 2001

ISSN

0366-6999

Associated Experts

Damu Tang

Associate Professor (Part-Time), Faculty of Health Sciences

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Fields of Research (FoR)

32 Biomedical and Clinical Sciences 3209 Neurosciences 3201 Cardiovascular medicine and haematology

Medical Subject Headings (MeSH)

Animals Blotting, Western Cyclin-Dependent Kinase 5 Cyclin-Dependent Kinases Hippocampus Immunohistochemistry Kindling, Neurologic Male Nerve Tissue Proteins Rats Rats, Wistar