Heat-Shock Proteins Concept

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• 4‐Phenylbutyrate protects against atherosclerotic lesion growth by increasing the expression of HSP25 in macrophages and in the circulation of Apoe ^−/− mice  Journal Articles
• Escherichia coli toxin/antitoxin pair MqsR/MqsA regulate toxin CspD  Journal Articles
• N‐acetyllactosamine‐induced retraction of bundle‐forming pili regulates virulence‐associated gene expression in enteropathogenic Escherichia coli  Journal Articles
• A Fatal, Systemic Mitochondrial Disease with Decreased Mitochondrial Enzyme Activities, Abnormal Ultrastructure of the Mitochondria and Deficiency of Heat Shock Protein 60  Journal Articles
• A Method for Expression and Purification of Soluble, Active Hsp47, a Collagen-Specific Molecular Chaperone  Journal Articles
• A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers  Conferences
• A practical model of low-volume high-intensity interval training induces mitochondrial biogenesis in human skeletal muscle: potential mechanisms  Journal Articles
• AMP-Activated Protein Kinase-Regulated Activation of the PGC-1α Promoter in Skeletal Muscle Cells  Journal Articles
• AMP‐activated protein kinase is required for exercise‐induced peroxisome proliferator‐activated receptor γ co‐activator 1α translocation to subsarcolemmal mitochondria in skeletal muscle  Journal Articles
• Acidic pH changes receptor binding specificity of Helicobacter pylori: a binary adhesion model in which surface heat shock (stress) proteins mediate sulfatide recognition in gastric colonization  Journal Articles
• Activated protein C modulates inflammation, apoptosis and tissue factor procoagulant activity by regulating endoplasmic reticulum calcium depletion in blood monocytes  Journal Articles
• Activation of Synovial Fluid T Lymphocytes by 60‐Kd Heat‐Shock Proteins in Patients with Inflammatory synovitis  Journal Articles
• Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease  Journal Articles
• Acute endurance exercise increases the nuclear abundance of PGC-1α in trained human skeletal muscle  Journal Articles
• Acute β-adrenergic stimulation does not alter mitochondrial protein synthesis or markers of mitochondrial biogenesis in adult men  Journal Articles
• Alterations in Mitochondrial and Apoptosis‐regulating Gene Expression in Photodynamic Therapy‐resistant Variants of HT29 Colon Carcinoma Cells^¶  Journal Articles
• An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1α and activates mitochondrial biogenesis in human skeletal muscle  Journal Articles
• Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions  Journal Articles
• Apatorsen plus docetaxel versus docetaxel alone in platinum-resistant metastatic urothelial carcinoma (Borealis-2)  Journal Articles
• Apoptosis and other effects of radiation in normal human urothelial cells  Journal Articles
• Association of Multiple Cellular Stress Pathways With Accelerated Atherosclerosis in Hyperhomocysteinemic Apolipoprotein E-Deficient Mice  Journal Articles
• Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor  Journal Articles
• Beyond mitochondria: Alternative energy-producing pathways from all strata of life  Journal Articles
• Binding of Anti-GRP78 Autoantibodies to Cell Surface GRP78 Increases Tissue Factor Procoagulant Activity via the Release of Calcium from Endoplasmic Reticulum Stores  Journal Articles
• Brief intense interval exercise activates AMPK and p38 MAPK signaling and increases the expression of PGC-1α in human skeletal muscle  Journal Articles
• Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humans  Journal Articles
• Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy  Journal Articles
• Characterization of the stress-inducing effects of homocysteine  Journal Articles
• Cigarette Smoke Exposure Leads to Follicle Loss via an Alternative Ovarian Cell Death Pathway in a Mouse Model  Journal Articles
• Cloning and characterization of multiple groEL chaperonin-encoding genes in Rhizobium meliloti  Journal Articles
• Cloning of Giardia lamblia heat shock protein HSP70 homologs: implications regarding origin of eukaryotic cells and of endoplasmic reticulum.  Journal Articles
• Cloning of HSP60 (GroEL) operon from Clostridium perfringens using a polymerase chain reaction based approach  Journal Articles
• Cloning of HSP70 (dnaK) gene from Clostridium perfringens using a general polymerase chain reaction based approach  Journal Articles
• Cloning of a Chinese hamster protein homologous to the mouse t-complex protein TCP-1: Structural similarity to the ubiquitous ‘chaperonin’ family of heat-shock proteins  Journal Articles
• Cloning of the HSP70 gene from Halobacterium marismortui: relatedness of archaebacterial HSP70 to its eubacterial homologs and a model for the evolution of the HSP70 gene  Journal Articles
• Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial–lysosomal axis and alleviates autophagic blockage in Pompe disease  Journal Articles
• Concurrent resistance and aerobic exercise stimulates both myofibrillar and mitochondrial protein synthesis in sedentary middle-aged men  Journal Articles
• Cooperative Interactions between Androgen Receptor (AR) and Heat-Shock Protein 27 Facilitate AR Transcriptional Activity  Journal Articles
• Danger, diversity and priming in innate antiviral immunity  Journal Articles
• Diabetes and heat shock protein  Journal Articles
• ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death  Journal Articles
• Endoplasmic Reticulum Chaperone GRP78 Protects Heart From Ischemia/Reperfusion Injury Through Akt Activation  Journal Articles
• Endoplasmic Reticulum Chaperone Protein GRP78 Protects Cells from Apoptosis Induced by Topoisomerase Inhibitors  Journal Articles
• Enhancement in amount of P1 (hsp60) in mutants of Chinese hamster ovary (CHO-K1) cells exhibiting increases in the A system of amino acid transport.  Journal Articles
• Evidence of Endoplasmic Reticulum Stress Mediating Cell Death in Transplanted Human Islets  Journal Articles
• Evolution of HSP70 gene and its implications regarding relationships between archaebacteria, eubacteria, and eukaryotes  Journal Articles
• Evolutionary relationships among photosynthetic prokaryotes (Heliobacterium chlorum, Chloroflexus aurantiacus, cyanobacteria, Chlorobium tepidum and proteobacteria): implications regarding the origin of photosynthesis  Journal Articles
• Exercise, sex, menstrual cycle phase, and 17β-estradiol influence metabolism-related genes in human skeletal muscle  Journal Articles
• Expression of Human 60-kD Heat Shock Protein (HSP60 or P1) inEscherichia coliand the Development and Characterization of Corresponding Monoclonal Antibodies  Journal Articles
• Expression of recombinant human casein kinase II and recombinant heat shock protein 90 in Escherichia coli and characterization of their interactions.  Journal Articles
• Extracellular Heat Shock Proteins as Therapeutic Targets and Biomarkers in Fibrosing Interstitial Lung Diseases  Journal Articles
• GRP78 (Glucose-Regulated Protein of 78 kDa) Promotes Cardiomyocyte Growth Through Activation of GATA4 (GATA-Binding Protein 4)  Journal Articles
• GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis  Journal Articles
• Genomic and transcriptomic analyses of the tangerine pathotype of Alternaria alternata in response to oxidative stress  Journal Articles
• Getting a GRP on Tissue Factor Activation  Journal Articles
• Glucosamine-Induced Endoplasmic Reticulum Stress Promotes ApoB100 Degradation  Journal Articles
• Glucose‐regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders  Journal Articles
• Guanosine protects against reperfusion injury in rat brains after ischemic stroke  Journal Articles
• Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling  Journal Articles
• Heat shock protein: a hot topic in idiopathic pulmonary fibrosis  Journal Articles
• Heat shock transcription factors regulate heat induced cell death in a rat histiocytoma  Journal Articles
• High-intensity interval training increases SIRT1 activity in human skeletal muscle  Journal Articles
• Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways  Journal Articles
• Human peripheral gamma delta T cells recognize hsp60 molecules on Daudi Burkitt's lymphoma cells.  Journal Articles
• Humoral and cellular immune recognition of Helicobacter pylori proteins are not concordant  Journal Articles
• Identification of Small Molecule Chemical Inhibitors of the Collagen-Specific Chaperone Hsp47  Journal Articles
• Identification of a hTid‐1 mutation which sensitizes gliomas to apoptosis  Journal Articles
• Identification of a protein altered in mutants resistant to microtubule inhibitors as a member of the major heat shock protein (hsp70) family.  Journal Articles
• Identification of endoplasmic reticulum in the primitive eukaryote Giardia lamblia using cryoelectron microscopy and antibody to BiP  Journal Articles
• Immunocytochemical localization of heat-shock protein 60-related protein in Beta-cell secretory granules and its altered distribution in non-obese diabetic mice  Journal Articles
• Impaired endoplasmic reticulum stress response in bipolar disorder: cellular evidence of illness progression  Journal Articles
• Increased BNip3 and decreased mutant p53 in cisplatin-sensitive PDT-resistant HT29 cells  Journal Articles
• Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition  Journal Articles
• Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained  Journal Articles
• Low-Volume Interval Training Improves Muscle Oxidative Capacity in Sedentary Adults  Journal Articles
• Manganese superoxide dismutase and heat shock protein 70 are not necessary for suppression of apoptosis in human peripheral blood neutrophils.  Journal Articles
• Mapping Hsp47 binding site(s) using CNBr peptides derived from type I and type II collagen  Journal Articles
• Massage Therapy Attenuates Inflammatory Signaling After Exercise-Induced Muscle Damage  Journal Articles
• Matched work high-intensity interval and continuous running induce similar increases in PGC-1α mRNA, AMPK, p38, and p53 phosphorylation in human skeletal muscle  Journal Articles
• Men supplemented with 17β-estradiol have increased β-oxidation capacity in skeletal muscle  Journal Articles
• Menin Is a Regulator of the Stress Response in Drosophila melanogaster  Journal Articles
• Metabolic Adaptations to Short-term High-Intensity Interval Training  Journal Articles
• Metabolic Syndrome and Acute Hyperglycemia Are Associated With Endoplasmic Reticulum Stress in Human Mononuclear Cells  Journal Articles
• Microtubules, mitochondria, and molecular chaperones: a new hypothesis for in vivo assembly of microtubules  Journal Articles
• Mitochondria, molecular chaperone proteins and the in vivo assembly of microtubules  Journal Articles
• Mitochondrial import of the human chaperonin (HSP60) protein  Journal Articles
• Mitochondrial precursor protein. Effects of 70-kilodalton heat shock protein on polypeptide folding, aggregation, and import competence.  Journal Articles
• Modulation of adjuvant arthritis in Lewis rats by recombinant vaccinia virus expressing the human 60-kilodalton heat shock protein  Journal Articles
• Molecular cloning, localization and characterization of a 40‐kDa catecholamine‐regulated protein  Journal Articles
• Mycobacteria and human heat shock protein—specific cytotoxic t lymphocytes in rheumatoid synovial inflammation  Journal Articles
• Nuclear SIRT1 activity, but not protein content, regulates mitochondrial biogenesis in rat and human skeletal muscle  Journal Articles
• Nucleotide Sequences and Novel Structural Features of Human and Chinese Hamster hsp60 (Chaperonin) Gene Families  Journal Articles
• Nucleotide sequence of mouse HSP60 (chaperonin, GroEL homolog) cDNA  Journal Articles
• Nucleotide sequence of rat hsp60 (chaperonin, GroEL homolog) cDNA  Journal Articles
• Overexpression of the 78-kDa Glucose-regulated Protein/Immunoglobulin-binding Protein (GRP78/BiP) Inhibits Tissue Factor Procoagulant Activity  Journal Articles
• PGC-1α's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1α and PGC-1β protein  Journal Articles
• PGC‐1α gene expression is down‐regulated by Akt‐mediated phosphorylation and nuclear exclusion of FoxO1 in insulin‐stimulated skeletal muscle  Journal Articles
• Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death  Journal Articles
• Photodynamic Therapy Resistant Human Colon Carcinoma HT29 Cells Show Cross‐Resistance to UVA but not UVC Light  Journal Articles
• Phylogenetic Analysis of Mycoplasmas Based on Hsp70 Sequences: Cloning of the dnaK (hsp70) Gene Region of Mycoplasma capricolum  Journal Articles
• Potentiation of Aminoglycoside Activity in Pseudomonas aeruginosa by Targeting the AmgRS Envelope Stress-Responsive Two-Component System  Journal Articles
• Presence and Cellular Distribution of a 60-kDa Protein Related to Mitochondrial HSP60 in Giardia lamblia  Journal Articles
• Primary structure of a human mitochondrial protein homologous to the bacterial and plant chaperonins and to the 65-kilodalton mycobacterial antigen.  Journal Articles
• Proteomic Profiling of Hepatic Endoplasmic Reticulum-associated Proteins in an Animal Model of Insulin Resistance and Metabolic Dyslipidemia  Journal Articles
• Proteomic changes in the rat brain induced by homogenous irradiation and by the bystander effect resulting from high energy synchrotron X-ray microbeams  Journal Articles
• Proteotoxicity and Cardiac Dysfunction — Alzheimer's Disease of the Heart?  Journal Articles
• Regulation of Heat and Radiation Stress Responses in Yeast by hsp-104  Journal Articles
• Role of Endoplasmic Reticulum Calcium Disequilibria in the Mechanism of Homocysteine-Induced ER Stress  Journal Articles
• RpoS regulation of gene expression during exponential growth of Escherichia coli K12  Journal Articles
• Secretory granule autoantigen in insulin-dependent diabetes mellitus is related to 62 kDa heat-shock protein (hsp60)  Journal Articles
• Sequence and structural homology between a mouse T-complex protein TCP-1 and the 'chaperonin' family of bacterial (GroEL, 60-65 kDa heat shock antigen) and eukaryotic proteins.  Journal Articles
• Similar metabolic adaptations during exercise after low volume sprint interval and traditional endurance training in humans  Journal Articles
• Small Molecules Targeting GRP78 Mitigate Anti- GRP78 Autoantibody-Mediated Tissue Factor Procoagulant Activity in Cultured Endothelial Cells  Journal Articles
• Staining of endothelial cells and macrophages in atherosclerotic lesions with human heat-shock protein-reactive antisera.  Journal Articles
• Stressproteine bei der Pathogenese des Prostatakarzinoms  Journal Articles
• Structure–function studies on Hsp47: pH-dependent inhibition of collagen fibril formation in vitro  Journal Articles
• Systemic administration of guanosine promotes functional and histological improvement following an ischemic stroke in rats  Journal Articles
• The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-β Oligomer Toxicity  Journal Articles
• The Unfolded Protein Response in Health and Disease  Journal Articles
• The environmental and genetic regulation of obake expressivity: morphogenetic fields as evolvable systems  Journal Articles
• The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury  Journal Articles
• The phylogeny of proteobacteria: relationships to other eubacterial phyla and eukaryotes  Journal Articles
• The sequences of heat shock protein 40 (DnaJ) homologs provide evidence for a close evolutionary relationship between the Deinococcus- Thermus group and cyanobacteria  Journal Articles
• The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout  Journal Articles
• Transcriptome data reveal conserved patterns of fruiting body development and response to heat stress in the mushroom-forming fungus Flammulina filiformis  Journal Articles
• Translational activation of maternal mRNA encoding the heat-shock protein hsp90 during sea urchin embryogenesis  Journal Articles
• Unusual Cellular Disposition of the Mitochondrial Molecular Chaperones Hsp60, Hsp70 and Hsp10  Journal Articles
• Up-regulation of Hsp27 Plays a Role in the Resistance of Human Colon Carcinoma HT29 Cells to Photooxidative Stress¶  Journal Articles
• X-irradiation- and carcinogen-induced proteins in cultured CHO cells  Journal Articles