Journal article
Secretory granule autoantigen in insulin-dependent diabetes mellitus is related to 62 kDa heat-shock protein (hsp60)
Abstract
Recent studies in NOD mice suggest that cellular and humoral responses against beta cell protein(s) cross-reactive with mycobacterial heat-shock protein, hsp60, are implicated in the development of autoimmune diabetes. However, this putative, hsp60-related autoantigen has not yet been identified nor have the preceding events triggering the autoimmunity against it. Our recent studies show that antibodies to the mammalian hsp60 bind specifically …
Authors
Brudzynski K; Martinez V; Gupta RS
Journal
Journal of Autoimmunity, Vol. 5, No. 4, pp. 453–463
Publisher
Elsevier
Publication Date
August 1992
DOI
10.1016/0896-8411(92)90005-b
ISSN
0896-8411