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Enhancement in amount of P1 (hsp60) in mutants of...
Journal article

Enhancement in amount of P1 (hsp60) in mutants of Chinese hamster ovary (CHO-K1) cells exhibiting increases in the A system of amino acid transport.

Abstract

Mutants of CHO-K1 cells with varied levels of A system activity, probably the result of increases in absolute amount of the A system transporter, have corresponding increases in levels of peptides banding at 62-66 and 29 kDa. Mutant alar4-H3.9, showing the highest increase of A system activity and of 62- to 66- and 29-kDa peptides, was selected for this study. The N terminus 16-amino acid sequence of the 62- to 66-kDa peptide(s) of this mutant …

Authors

Jones M; Gupta RS; Englesberg E

Journal

Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 3, pp. 858–862

Publisher

Proceedings of the National Academy of Sciences

Publication Date

2 1994

DOI

10.1073/pnas.91.3.858

ISSN

0027-8424