CD4-Positive T-Lymphocytes Concept

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• Ahnak-knockout mice show susceptibility toBartonella henselaeinfection because of CD4+ T cell inactivation and decreased cytokine secretion  Journal Articles
• A Human Type 5 Adenovirus–Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus Immunity  Journal Articles
• A Switch in Costimulation from CD28 to 4-1BB during Primary versus Secondary CD8 T Cell Response to Influenza In Vivo  Journal Articles
• A randomized controlled trial of HIV therapeutic vaccination using ALVAC with or without Remune  Journal Articles
• A role for CD4⁺ T cells in the pathogenesis of skin fibrosis in tight skin mice  Journal Articles
• ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes  Journal Articles
• Activation of CD8 T Cells by Mycobacterial Vaccination Protects against Pulmonary Tuberculosis in the Absence of CD4 T Cells  Journal Articles
• Adaptive Resistance to Cancer Immunotherapy  Journal Articles
• Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial  Journal Articles
• Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models  Journal Articles
• Adenoviral-Mediated Gene Transfer of Lymphotactin to the Lungs of Mice and Rats Results in Infiltration and Direct Accumulation of CD4⁺, CD8⁺, and NK Cells  Journal Articles
• Adoptive Cell Therapy Using In Vitro Generated Human CD4+CD25+ Regulatory T Cells With Indirect Allospecificity to Promote Donor-Specific Transplantation Tolerance  Journal Articles
• Autoimmune VariantPTPN22C1858T Is Associated With Impaired Responses to Influenza Vaccination  Journal Articles
• Behavioral heterogeneity in an animal model of neuropsychiatric lupus  Journal Articles
• Benralizumab attenuates airway eosinophilia in prednisone-dependent asthma  Journal Articles
• CD11c+ antigen presenting cells from the alveolar space, lung parenchyma and spleen differ in their phenotype and capabilities to activate naïve and antigen-primed T cells  Journal Articles
• CD4 T Cells and Major Histocompatibility Complex Class II Expression Influence Worm Expulsion and Increased Intestinal Muscle Contraction duringTrichinella spiralisInfection  Journal Articles
• CD4+ T cell-mediated immunological control of enterochromaffin cell hyperplasia and 5-hydroxytryptamine production in enteric infection  Journal Articles
• CD4+ T-Cell Modulation of Visceral Nociception in Mice  Journal Articles
• CD4+ T-cells are important in regulating macrophage polarization in C57BL/6 wild-type mice  Journal Articles
• CD4⁺ T‐cell‐mediated anti‐tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis  Journal Articles
• CD4⁺T-cell recovery after initiation of antiretroviral therapy in a resource-limited setting: A prospective cohort analysis  Journal Articles
• CD56 ^bright natural killer regulatory cells in filgrastim primed donor blood or marrow products regulate chronic graft- versus -host disease: the Canadian Blood and Marrow Transplant Group randomized 0601 study results  Journal Articles
• CELL SURFACE LOCALIZATION OF THE 60 kDa HEAT SHOCK CHAPERONIN PROTEIN (hsp60) IN MAMMALIAN CELLS  Journal Articles
• Cat allergen peptide immunotherapy reduces CD4⁺ T cell responses to cat allergen but does not alter suppression by CD4⁺ CD25⁺ T cells: a double‐blind placebo‐controlled study  Journal Articles
• Changes in interferon‐γ production following specific allergen immunotherapy: biology vs methodology  Journal Articles
• Chemokine Receptor CXCR3 Expression in Inflammatory Bowel Disease  Journal Articles
• Chronic Brucellosis Patients Retain Low Frequency of CD4+ T-Lymphocytes Expressing CD25 and CD28 afterEscherichia coliLPS Stimulation of PHA-Cultured PBMCs  Journal Articles
• Chronic Immune Activation and CD4+ T Cell Lymphopenia in Healthy African Individuals: Perspectives for SARS-CoV-2 Vaccine Efficacy  Journal Articles
• Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice  Journal Articles
• Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity  Journal Articles
• Combined protein and nucleic acid imaging reveals virus-dependent B cell and macrophage immunosuppression of tissue microenvironments  Journal Articles
• Comparing Current and Next-Generation Humanized Mouse Models for Advancing HIV and HIV/Mtb Co-Infection Studies  Journal Articles
• Concomitant airway expression of granulocyte‐macrophage colony‐stimulating factor and decorin, a natural inhibitor of transforming growth factor‐β, breaks established inhalation tolerance  Journal Articles
• Continuous and Discontinuous Cigarette Smoke Exposure Differentially Affects Protective Th1 Immunity against Pulmonary Tuberculosis  Journal Articles
• Control of Pathogenic CD4 T Cells and Lethal Immunopathology by Signaling Immunoadaptor DAP12 during Influenza Infection  Journal Articles
• Costimulation Through CD86 Is Involved in Airway Antigen-Presenting Cell and T Cell Responses to Allergen in Atopic Asthmatics  Journal Articles
• Critical Role of Natural Killer Cells in Lung Immunopathology During Influenza Infection in Mice  Journal Articles
• Cytotoxic T-lymphocytes from HIV-infected individuals recognize an activation-dependent, non-polymorphic molecule on uninfected CD4+ lymphocytes  Journal Articles
• Decreased CTLA4+ and Foxp3+ CD25highCD4+ Cells in Induced Sputum from Patients with Mild Atopic Asthma  Journal Articles
• Dendritic Cell-Derived IL-12 Is Not Required for the Generation of Cytotoxic, IFN-γ-Secreting, CD8+ CTL In Vivo  Journal Articles
• Design, characterization and testing of tRNA3Lys-based hammerhead ribozymes  Journal Articles
• Determinants of CD4 Counts Among HIV-Negative Ethiopians: Role of Body Mass Index, Gender, Cigarette Smoking, Khat (Catha Edulis) Chewing, and Possibly Altitude?  Journal Articles
• Development of Cell-Based Tuberculosis Vaccines: Genetically Modified Dendritic Cell Vaccine Is a Much More Potent Activator of CD4 and CD8 T Cells Than Peptide- or Protein-Loaded Counterparts  Journal Articles
• Different profiles of T-cell IFN-γ and IL-12 in allergen-induced early and dual responders with asthma  Journal Articles
• Differential Elevation of Inflammation and CD4+ T Cell Activation in Kenyan Female Sex Workers and Non-Sex Workers Using Depot-Medroxyprogesterone Acetate  Journal Articles
• Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model  Journal Articles
• Disruption of M-T5, a novel myxoma virus gene member of poxvirus host range superfamily, results in dramatic attenuation of myxomatosis in infected European rabbits  Journal Articles
• Early Intestinal Th1 Inflammation and Mucosal T Cell Recruitment During Acute Graft-Versus-Host Reaction  Journal Articles
• Effects of inhaled ciclesonide on circulating T‐helper type 1/T‐helper type 2 cells in atopic asthmatics after allergen challenge  Journal Articles
• Effects of inhaled fluticasone propionate on CTLA‐4‐positive CD4+CD25+ cells in induced sputum in mild asthmatics  Journal Articles
• Electroporation Enables Plasmid Vaccines to Elicit CD8+ T Cell Responses in the Absence of CD4+ T Cells  Journal Articles
• Elevated Frequencies of Self-reactive CD8+ T Cells following Immunization with a Xenoantigen Are Due to the Presence of a Heteroclitic CD4+ T-Cell Helper Epitope  Journal Articles
• Endometrial epithelial cell response to semen from HIV-infected men during different stages of infection is distinct and can drive HIV-1-long terminal repeat  Journal Articles
• Enhanced HER-2/neu-specific antitumor immunity by cotransduction of mouse dendritic cells with two genes encoding HER-2/neu and alpha tumor necrosis factor  Journal Articles
• Enhanced immunogenicity of BCG vaccine by using a viral-based GM-CSF transgene adjuvant formulation  Journal Articles
• Enhancement of Antituberculosis Immunity in a Humanized Model System by a Novel Virus-Vectored Respiratory Mucosal Vaccine  Journal Articles
• Estradiol Enhances Antiviral CD4⁺Tissue-Resident Memory T Cell Responses following Mucosal Herpes Simplex Virus 2 Vaccination through an IL-17-Mediated Pathway  Journal Articles
• Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway  Journal Articles
• Evaluation of the preclinical analgesic efficacy of naturally derived, orally administered oil forms of Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD), and their 1:1 combination  Journal Articles
• Expression of Chemokine Receptors CCR5 and CXCR4 on CD4+ T Cells and Plasma Chemokine Levels During Treatment of Active Tuberculosis in HIV-1-Coinfected Patients  Journal Articles
• Expression of Dual TCR on DO11.10 T Cells Allows for Ovalbumin-Induced Oral Tolerance to Prevent T Cell-Mediated Colitis Directed against Unrelated Enteric Bacterial Antigens  Journal Articles
• Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics.  Journal Articles
• FoxP3 overexpression and CD1a+ and CD3+ depletion in anal tissue as possible mechanisms for increased risk of human papillomavirus-related anal carcinoma in HIV infection  Journal Articles
• Functional characterization of CD4+ T cell receptors crossreactive for SARS-CoV-2 and endemic coronaviruses  Journal Articles
• GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice.  Journal Articles
• Gamma Interferon Responses of CD4 and CD8 T-Cell Subsets Are Quantitatively Different and Independent of Each Other during PulmonaryMycobacterium bovisBCG Infection  Journal Articles
• Genetically modified dendritic cells prime autoreactive T cells through a pathway independent of CD40L and interleukin 12: implications for cancer vaccines.  Journal Articles
• Gluten-Dependent Activation of CD4+ T Cells by MHC Class II–Expressing Epithelium  Journal Articles
• Gut commensal microvesicles reproduce parent bacterial signals to host immune and enteric nervous systems  Journal Articles
• HERV-K–specific T cells eliminate diverse HIV-1/2 and SIV primary isolates  Journal Articles
• HIV‐serology and lymphocyte subsets in relation to therapy and clinical development in haemophiliacs  Journal Articles
• Hematopoietic Processes in Eosinophilic Asthma  Journal Articles
• Herpes Simplex Virus Type 2 Coinfection Does Not Accelerate CD4 Count Decline in Untreated HIV Infection  Journal Articles
• Herpes simplex virus-2 in the genital mucosa  Journal Articles
• Heterologous Boosting of Recombinant Adenoviral Prime Immunization With a Novel Vesicular Stomatitis Virus–vectored Tuberculosis Vaccine  Journal Articles
• IL-10 production in circulating T cells differs between allergen-induced isolated early and dual asthmatic responders  Journal Articles
• IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: Relationship to expression of allergic disease  Journal Articles
• Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells  Journal Articles
• Immune recovery in HIV-1 infected patients with sustained viral suppression under long-term antiretroviral therapy in Ethiopia  Journal Articles
• Immune response to changes in training intensity and volume in runners  Journal Articles
• Immunopathology in influenza virus infection: Uncoupling the friend from foe  Journal Articles
• Immunophenotyping of blood lymphocytes at birth, during childhood, and during adulthood in HIV-1-uninfected Ethiopians  Journal Articles
• Immunosenescence in the nursing home elderly  Journal Articles
• Impact of Standard Bacterial Vaginosis Treatment on the Genital Microbiota, Immune Milieu, and Ex Vivo Human Immunodeficiency Virus Susceptibility  Journal Articles
• Impact of hepatitis C viral replication on CD4+ T-lymphocyte progression in HIV–HCV coinfection before and after antiretroviral therapy  Journal Articles
• In vitro analysis of the herbal compound Essiac.  Journal Articles
• In vitro expanded alloantigen-specific CD4+CD25+ regulatory T cell treatment for the induction of donor-specific transplantation tolerance  Journal Articles
• In-vitro generation and characterisation of murine CD4+CD25+ regulatory T cells with indirect allospecificity  Journal Articles
• Indirect Recognition of T-Cell Epitopes Derived from the α3 and Transmembrane Domain of HLA-A2  Journal Articles
• Induced sputum, bronchoalveolar lavage and blood from mild asthmatics: inflammatory cells, lymphocyte subsets and soluble markers compared  Journal Articles
• Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12  Journal Articles
• Influence of breastfeeding versus formula feeding on lymphocyte subsets in infants at risk of coeliac disease: the PROFICEL study  Journal Articles
• Influence of the Tissue Microenvironment on Toll-Like Receptor Expression by CD11c⁺Antigen-Presenting Cells Isolated from Mucosal Tissues  Journal Articles
• Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice  Journal Articles
• Inhibition of HIV replication by CD8+ T cells correlates with CD4 counts and clinical stage of disease  Journal Articles
• Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism  Journal Articles
• Innate and adaptive immunity against herpes simplex virus type 2 in the genital mucosa  Journal Articles
• Interactions Between the Immune System and Cancer: A Brief Review of Non-spatial Mathematical Models  Journal Articles
• Interleukin-18 expression, CD8+ T cells, and eosinophils in lungs of nonsmokers with fatal asthma  Journal Articles
• Interrupting reactivation of immunologic memory diverts the allergic response and prevents anaphylaxis  Journal Articles
• Intramuscular immunization with a monogenic plasmid DNA tuberculosis vaccine: Enhanced immunogenicity by electroporation and co-expression of GM-CSF transgene  Journal Articles
• Intranasal Boosting with an Adenovirus-Vectored Vaccine Markedly Enhances Protection by Parenteral Mycobacterium bovis BCG Immunization against Pulmonary Tuberculosis  Journal Articles
• Invariant NKT cells sustain specific B cell responses and memory  Journal Articles
• Is it still worthwhile to perform quarterly cd4+ t lymphocyte cell counts on hiv-1 infected stable patients?  Journal Articles
• Low CD4 T Cell Counts before HIV‐1 Seroconversion Do Not Affect Disease Progression in Ethiopian Factory Workers  Journal Articles
• Lymphocyte-mediated regulation of β-endorphin in the myenteric plexus  Journal Articles
• Lysis of CD4+ lymphocytes by non-HLA-restricted cytotoxic T lymphoe from HIV-infected individuals  Journal Articles
• Mechanisms of Mucosal and Parenteral Tuberculosis Vaccinations: Adenoviral-Based Mucosal Immunization Preferentially Elicits Sustained Accumulation of Immune Protective CD4 and CD8 T Cells within the Airway Lumen  Journal Articles
• Mesenchymal Stromal Cells but Not Cardiac Fibroblasts Exert Beneficial Systemic Immunomodulatory Effects in Experimental Myocarditis  Journal Articles
• Morphometric analysis of inflammation in bronchial biopsies following exposure to inhaled diesel exhaust and allergen challenge in atopic subjects  Journal Articles
• Mucosal-Pull Induction of Lung-Resident Memory CD8 T Cells in Parenteral TB Vaccine-Primed Hosts Requires Cognate Antigens and CD4 T Cells  Journal Articles
• NET-EN treatment leads to delayed HSV-2 infection, enhanced mucin and T cell functions in the female genital tract when compared to DMPA in a preclinical mouse model.  Journal Articles
• NK cells require antigen-specific memory CD4+ T cells to mediate superior effector functions during HSV-2 recall responses in vitro  Journal Articles
• Normalization of obesity-associated insulin resistance through immunotherapy  Journal Articles
• Novel Role for Interleukin-17 in Enhancing Type 1 Helper T Cell Immunity in the Female Genital Tract following Mucosal Herpes Simplex Virus 2 Vaccination  Journal Articles
• Of cats and men: immunodominance and the role of HLA‐DP/DQ  Journal Articles
• On the Role of CD4+ T Cells in the CD8+ T-Cell Response Elicited by Recombinant Adenovirus Vaccines  Journal Articles
• Oncostatin M induces IL-33 expression in liver endothelial cells in mice and expands ST2⁺CD4⁺lymphocytes  Journal Articles
• Overexpression of Interleukin-15 Compromises CD4-Dependent Adaptive Immune Responses against Herpes Simplex Virus 2  Journal Articles
• Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population  Journal Articles
• Processing of Tumor Antigen Differentially Impacts the Development of Helper and Effector CD4+ T-cell Responses  Journal Articles
• Protection by CD4 or CD8 T Cells against PulmonaryMycobacterium bovisBacillus Calmette-Guérin Infection  Journal Articles
• Protein kinase A-catalyzed phosphorylation of heat shock protein 60 chaperone regulates its attachment to histone 2B in the T lymphocyte plasma membrane  Journal Articles
• Radiation-Induced Lymphocyte Apoptosis to Predict Radiation Therapy Late Toxicity in Prostate Cancer Patients  Journal Articles
• Recombinant Adenovirus Vaccines Can Successfully Elicit CD8+ T Cell Immunity under Conditions of Extreme Leukopenia  Journal Articles
• Reduced amount of intestinal mucus by treatment with anti‐CD4 antibody interferes with the spontaneous cure of Nippostrongylus brasiliensis‐infection in mice  Journal Articles
• Repeated Seasonal Influenza Vaccination: How Much Is Too Much of a Good Thing?  Journal Articles
• Respiratory macrophages regulate CD4 T memory responses to mucosal immunization with recombinant adenovirus-based vaccines  Journal Articles
• Role of incidental and/or cured intestinal parasitic infections on profile of CD4+ and CD8+ T cell subsets and activation status in HIV-1 infected and uninfected adult Ethiopians  Journal Articles
• Role ofLeishmania donovaniand Its Lipophosphoglycan in CD4⁺T-cell Activation-Induced Human Immunodeficiency Virus Replication  Journal Articles
• SARS-CoV-2 vaccination diversifies the CD4+ spike-reactive T cell repertoire in patients with prior SARS-CoV-2 infection  Journal Articles
• Sensitization to Gliadin Induces Moderate Enteropathy and Insulitis in Nonobese Diabetic-DQ8 Mice  Journal Articles
• Serotonin Activates Dendritic Cell Function in the Context of Gut Inflammation  Journal Articles
• Severe mental illness at ART initiation is associated with worse retention in care among HIV‐infected Ugandan adults  Journal Articles
• Single Mucosal, but Not Parenteral, Immunization with Recombinant Adenoviral-Based Vaccine Provides Potent Protection from Pulmonary Tuberculosis  Journal Articles
• Sputum T lymphocytes in asthma, COPD and healthy subjects have the phenotype of activated intraepithelial T cells (CD69+ CD103+)  Journal Articles
• Stable pattern of HIV-1 subtype C Gag-specific T-cell responses coincides with slow rate of CD4 T-cell decline in HIV-infected Ethiopians  Journal Articles
• Survival of HIV-Infected Adolescents on Antiretroviral Therapy in Uganda: Findings from a Nationally Representative Cohort in Uganda  Journal Articles
• T Cell Epitope Immunotherapy Induces a CD4+ T Cell Population with Regulatory Activity  Journal Articles
• T Cell-Derived Suppressive Activity: Evidence of Autocrine Noncytolytic Control of HIV Type 1 Transcription and Replication  Journal Articles
• T Lymphocyte Responses to Nonpolymorphic HLA-Derived Peptides Are Associated With Chronic Renal Allograft Dysfunction  Journal Articles
• T-cell immunity generated by recombinant adenovirus vaccines  Journal Articles
• T-cell-mediated inflammation does not contribute to the maintenance of airway dysfunction in mice  Journal Articles
• The Absence or Overexpression of IL-15 Drastically Alters Breast Cancer Metastasis via Effects on NK Cells, CD4 T Cells, and Macrophages  Journal Articles
• The Hayflick Limit May Determine the Effective Clonal Diversity of Naive T Cells  Journal Articles
• The Myxoma Virus M-T4 Gene Encodes a Novel RDEL-Containing Protein That Is Retained within the Endoplasmic Reticulum and Is Important for the Productive Infection of Lymphocytes  Journal Articles
• The Soluble Tachyzoite Antigen of Toxoplasma gondii Has a Protective Effect on Mouse Allografts  Journal Articles
• The anti‐idiotypic antibody 1F7 selectively inhibits cytotoxic T cells activated in HIV‐1 infection  Journal Articles
• The influence of lymphocyte counts and disease progression on circulating and inducible anti-HIV-1 cytotoxic T-cell activity in HIV-1-infected subjects  Journal Articles
• The novel CD4+CD25+ regulatory T cell effector molecule fibrinogen-like protein 2 contributes to the outcome of murine fulminant viral hepatitis  Journal Articles
• The potential of peptide immunotherapy in allergy and asthma  Journal Articles
• The role of CD4+ lymphocytes in the susceptibility of mice to stress-induced reactivation of experimental colitis  Journal Articles
• Timing of blood sampling for CD4 T-cell counting influences HAART decisions.  Journal Articles
• Tn-MUC1 DC Vaccination of Rhesus Macaques and a Phase I/II Trial in Patients with Nonmetastatic Castrate-Resistant Prostate Cancer  Journal Articles
• Tumor Protection Following Vaccination With Low Doses of Lentivirally Transduced DCs Expressing the Self-antigen erbB2  Journal Articles
• T‐Cell Phenotypes Predictive of Frailty and Mortality in Elderly Nursing Home Residents  Journal Articles
• Vaccination-Induced Autoimmune Vitiligo Is a Consequence of Secondary Trauma to the Skin  Journal Articles
• Visceral pain perception is determined by the duration of colitis and associated neuropeptide expression in the mouse  Journal Articles