CD4-Positive T-Lymphocytes Concept

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• A Human Type 5 Adenovirus–Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus Immunity  Academic Article
• A Switch in Costimulation from CD28 to 4-1BB during Primary versus Secondary CD8 T Cell Response to Influenza In Vivo  Academic Article
• A randomized controlled trial of HIV therapeutic vaccination using ALVAC with or without Remune  Academic Article
• A role for CD4+ T cells in the pathogenesis of skin fibrosis in tight skin mice  Academic Article
• ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes  Academic Article
• Activation of CD8 T Cells by Mycobacterial Vaccination Protects against Pulmonary Tuberculosis in the Absence of CD4 T Cells  Academic Article
• Adaptive Resistance to Cancer Immunotherapy  Academic Article
• Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial  Academic Article
• Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models  Academic Article
• Adenoviral-Mediated Gene Transfer of Lymphotactin to the Lungs of Mice and Rats Results in Infiltration and Direct Accumulation of CD4⁺, CD8⁺, and NK Cells  Academic Article
• Adoptive Cell Therapy Using In Vitro Generated Human CD4+CD25+ Regulatory T Cells With Indirect Allospecificity to Promote Donor-Specific Transplantation Tolerance  Academic Article
• Autoimmune VariantPTPN22C1858T Is Associated With Impaired Responses to Influenza Vaccination  Academic Article
• Behavioral heterogeneity in an animal model of neuropsychiatric lupus  Academic Article
• Benralizumab attenuates airway eosinophilia in prednisone-dependent asthma  Academic Article
• CD11c+ antigen presenting cells from the alveolar space, lung parenchyma and spleen differ in their phenotype and capabilities to activate naïve and antigen-primed T cells  Academic Article
• CD4 T Cells and Major Histocompatibility Complex Class II Expression Influence Worm Expulsion and Increased Intestinal Muscle Contraction during Trichinella spiralis Infection  Academic Article
• CD4+ T cell-mediated immunological control of enterochromaffin cell hyperplasia and 5-hydroxytryptamine production in enteric infection  Academic Article
• CD4+ T-Cell Modulation of Visceral Nociception in Mice  Academic Article
• CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis  Academic Article
• CD4+ T-cells are important in regulating macrophage polarization in C57BL/6 wild-type mice  Academic Article
• CD4⁺ T-cell recovery after initiation of antiretroviral therapy in a resource-limited setting: A prospective cohort analysis  Academic Article
• CD56 ^bright natural killer regulatory cells in filgrastim primed donor blood or marrow products regulate chronic graft- versus -host disease: the Canadian Blood and Marrow Transplant Group randomized 0601 study results  Academic Article
• CELL SURFACE LOCALIZATION OF THE 60 kDa HEAT SHOCK CHAPERONIN PROTEIN (hsp60) IN MAMMALIAN CELLS  Academic Article
• Cat allergen peptide immunotherapy reduces CD4+ T cell responses to cat allergen but does not alter suppression by CD4+ CD25+ T cells: a double-blind placebo-controlled study  Academic Article
• Changes in interferon-γ production following specific allergen immunotherapy: biology vs methodology  Academic Article
• Chemokine Receptor CXCR3 Expression in Inflammatory Bowel Disease  Academic Article
• Chronic Brucellosis Patients Retain Low Frequency of CD4+ T-Lymphocytes Expressing CD25 and CD28 afterEscherichia coliLPS Stimulation of PHA-Cultured PBMCs  Academic Article
• Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice  Academic Article
• Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity  Academic Article
• Combined protein and nucleic acid imaging reveals virus-dependent B cell and macrophage immunosuppression of tissue microenvironments  Academic Article
• Comparing Current and Next-Generation Humanized Mouse Models for Advancing HIV and HIV/Mtb Co-Infection Studies  Academic Article
• Concomitant airway expression of granulocyte-macrophage colony-stimulating factor and decorin, a natural inhibitor of transforming growth factor-β, breaks established inhalation tolerance  Academic Article
• Continuous and Discontinuous Cigarette Smoke Exposure Differentially Affects Protective Th1 Immunity against Pulmonary Tuberculosis  Academic Article
• Control of Pathogenic CD4 T Cells and Lethal Immunopathology by Signaling Immunoadaptor DAP12 during Influenza Infection  Academic Article
• Costimulation through CD86 is involved in airway antigen-presenting cell and T cell responses to allergen in atopic asthmatics.  Academic Article
• Critical Role of Natural Killer Cells in Lung Immunopathology During Influenza Infection in Mice  Academic Article
• Cytotoxic T-lymphocytes from HIV-infected individuals recognize an activation-dependent, non-polymorphic molecule on uninfected CD4+ lymphocytes  Academic Article
• Decreased CTLA4+ and Foxp3+ CD25highCD4+ Cells in Induced Sputum from Patients with Mild Atopic Asthma  Academic Article
• Dendritic Cell-Derived IL-12 Is Not Required for the Generation of Cytotoxic, IFN-γ-Secreting, CD8⁺CTL In Vivo  Academic Article
• Design, characterization and testing of tRNA3Lys-based hammerhead ribozymes  Academic Article
• Development of Cell-Based Tuberculosis Vaccines: Genetically Modified Dendritic Cell Vaccine Is a Much More Potent Activator of CD4 and CD8 T Cells Than Peptide- or Protein-Loaded Counterparts  Academic Article
• Different profiles of T-cell IFN-γ and IL-12 in allergen-induced early and dual responders with asthma  Academic Article
• Differential Elevation of Inflammation and CD4+ T Cell Activation in Kenyan Female Sex Workers and Non-Sex Workers Using Depot-Medroxyprogesterone Acetate  Academic Article
• Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model  Academic Article
• Disruption of M-T5, a novel myxoma virus gene member of poxvirus host range superfamily, results in dramatic attenuation of myxomatosis in infected European rabbits  Academic Article
• Early Intestinal Th1 Inflammation and Mucosal T Cell Recruitment During Acute Graft-Versus-Host Reaction  Academic Article
• Effects of inhaled ciclesonide on circulating T-helper type 1/T-helper type 2 cells in atopic asthmatics after allergen challenge  Academic Article
• Effects of inhaled fluticasone propionate on CTLA-4-positive CD4+CD25+ cells in induced sputum in mild asthmatics  Academic Article
• Electroporation Enables Plasmid Vaccines to Elicit CD8⁺T Cell Responses in the Absence of CD4⁺T Cells  Academic Article
• Elevated Frequencies of Self-reactive CD8+ T Cells following Immunization with a Xenoantigen Are Due to the Presence of a Heteroclitic CD4+ T-Cell Helper Epitope  Academic Article
• Endometrial epithelial cell response to semen from HIV-infected men during different stages of infection is distinct and can drive HIV-1-long terminal repeat  Academic Article
• Enhanced HER-2/neu-specific antitumor immunity by cotransduction of mouse dendritic cells with two genes encoding HER-2/neu and alpha tumor necrosis factor  Academic Article
• Enhanced immunogenicity of BCG vaccine by using a viral-based GM-CSF transgene adjuvant formulation  Academic Article
• Enhancement of Antituberculosis Immunity in a Humanized Model System by a Novel Virus-Vectored Respiratory Mucosal Vaccine  Academic Article
• Estradiol Enhances Antiviral CD4 ⁺ Tissue-Resident Memory T Cell Responses following Mucosal Herpes Simplex Virus 2 Vaccination through an IL-17-Mediated Pathway  Academic Article
• Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway  Academic Article
• Evaluation of the preclinical analgesic efficacy of naturally derived, orally administered oil forms of Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD), and their 1:1 combination  Academic Article
• Expression of Dual TCR on DO11.10 T Cells Allows for Ovalbumin-Induced Oral Tolerance to Prevent T Cell-Mediated Colitis Directed against Unrelated Enteric Bacterial Antigens  Academic Article
• Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics.  Academic Article
• FoxP3 overexpression and CD1a+ and CD3+ depletion in anal tissue as possible mechanisms for increased risk of human papillomavirus-related anal carcinoma in HIV infection  Academic Article
• Functional characterization of CD4+ T-cell receptors cross-reactive for SARS-CoV-2 and endemic coronaviruses  Academic Article
• GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice.  Academic Article
• Gamma Interferon Responses of CD4 and CD8 T-Cell Subsets Are Quantitatively Different and Independent of Each Other during Pulmonary Mycobacterium bovis BCG Infection  Academic Article
• Genetically modified dendritic cells prime autoreactive T cells through a pathway independent of CD40L and interleukin 12: implications for cancer vaccines.  Academic Article
• Gut commensal microvesicles reproduce parent bacterial signals to host immune and enteric nervous systems  Academic Article
• HERV-K–specific T cells eliminate diverse HIV-1/2 and SIV primary isolates  Academic Article
• HIV-serology and lymphocyte subsets in relation to therapy and clinical development in haemophiliacs  Academic Article
• Hematopoietic Processes in Eosinophilic Asthma  Academic Article
• Herpes Simplex Virus Type 2 Coinfection Does Not Accelerate CD4 Count Decline in Untreated HIV Infection  Academic Article
• Herpes simplex virus-2 in the genital mucosa  Academic Article
• Heterologous Boosting of Recombinant Adenoviral Prime Immunization With a Novel Vesicular Stomatitis Virus–vectored Tuberculosis Vaccine  Academic Article
• IL-10 production in circulating T cells differs between allergen-induced isolated early and dual asthmatic responders  Academic Article
• IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: Relationship to expression of allergic disease  Academic Article
• Immediate Dysfunction of Vaccine-Elicited CD8⁺ T Cells Primed in the Absence of CD4⁺ T Cells  Academic Article
• Immune response to changes in training intensity and volume in runners  Academic Article
• Immunopathology in influenza virus infection: Uncoupling the friend from foe  Academic Article
• Immunosenescence in the nursing home elderly  Academic Article
• Impact of Standard Bacterial Vaginosis Treatment on the Genital Microbiota, Immune Milieu, and Ex Vivo Human Immunodeficiency Virus Susceptibility  Academic Article
• Impact of hepatitis C viral replication on CD4+ T-lymphocyte progression in HIV–HCV coinfection before and after antiretroviral therapy  Academic Article
• In vitro analysis of the herbal compound Essiac.  Academic Article
• In vitro expanded alloantigen-specific CD4+CD25+ regulatory T cell treatment for the induction of donor-specific transplantation tolerance  Academic Article
• In-vitro generation and characterisation of murine CD4+CD25+ regulatory T cells with indirect allospecificity  Academic Article
• Indirect Recognition of T-Cell Epitopes Derived from the ?3 and Transmembrane Domain of HLA-A2  Academic Article
• Induced sputum, bronchoalveolar lavage and blood from mild asthmatics: inflammatory cells, lymphocyte subsets and soluble markers compared  Academic Article
• Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12  Academic Article
• Influence of breastfeeding versus formula feeding on lymphocyte subsets in infants at risk of coeliac disease: the PROFICEL study  Academic Article
• Influence of the Tissue Microenvironment on Toll-Like Receptor Expression by CD11c ⁺ Antigen-Presenting Cells Isolated from Mucosal Tissues  Academic Article
• Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice  Academic Article
• Inhibition of HIV replication by CD8+ T cells correlates with CD4 counts and clinical stage of disease  Academic Article
• Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion  Academic Article
• Inhibition of HIV-1-Induced Syncytia Formation and Infectivity by Lipophosphoglycan from Leishmania  Academic Article
• Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism  Academic Article
• Innate and adaptive immunity against herpes simplex virus type 2 in the genital mucosa  Academic Article
• Interactions Between the Immune System and Cancer: A Brief Review of Non-spatial Mathematical Models  Academic Article
• Interleukin-18 expression, CD8+ T cells, and eosinophils in lungs of nonsmokers with fatal asthma  Academic Article
• Interrupting reactivation of immunologic memory diverts the allergic response and prevents anaphylaxis  Academic Article
• Intramuscular immunization with a monogenic plasmid DNA tuberculosis vaccine: Enhanced immunogenicity by electroporation and co-expression of GM-CSF transgene  Academic Article
• Intranasal Boosting with an Adenovirus-Vectored Vaccine Markedly Enhances Protection by Parenteral Mycobacterium bovis BCG Immunization against Pulmonary Tuberculosis  Academic Article
• Invariant NKT cells sustain specific B cell responses and memory  Academic Article
• Is it still worthwhile to perform quarterly cd4+ t lymphocyte cell counts on hiv-1 infected stable patients?  Academic Article
• Lymphocyte-mediated regulation of β-endorphin in the myenteric plexus  Academic Article
• Lysis of CD4+ lymphocytes by non-HLA-restricted cytotoxic T lymphoe from HIV-infected individuals  Academic Article
• Mechanisms of Mucosal and Parenteral Tuberculosis Vaccinations: Adenoviral-Based Mucosal Immunization Preferentially Elicits Sustained Accumulation of Immune Protective CD4 and CD8 T Cells within the Airway Lumen  Academic Article
• Mesenchymal Stromal Cells but Not Cardiac Fibroblasts Exert Beneficial Systemic Immunomodulatory Effects in Experimental Myocarditis  Academic Article
• Morphometric analysis of inflammation in bronchial biopsies following exposure to inhaled diesel exhaust and allergen challenge in atopic subjects  Academic Article
• Mucosal-Pull Induction of Lung-Resident Memory CD8 T Cells in Parenteral TB Vaccine-Primed Hosts Requires Cognate Antigens and CD4 T Cells  Academic Article
• NK cells require antigen-specific memory CD4 ⁺ T cells to mediate superior effector functions during HSV-2 recall responses in vitro  Academic Article
• Normalization of obesity-associated insulin resistance through immunotherapy  Academic Article
• Novel Role for Interleukin-17 in Enhancing Type 1 Helper T Cell Immunity in the Female Genital Tract following Mucosal Herpes Simplex Virus 2 Vaccination  Academic Article
• Of cats and men: immunodominance and the role of HLA-DP/DQ  Academic Article
• On the Role of CD4+ T Cells in the CD8+ T-Cell Response Elicited by Recombinant Adenovirus Vaccines  Academic Article
• Oncostatin M induces IL-33 expression in liver endothelial cells in mice and expands ST2⁺CD4⁺lymphocytes  Academic Article
• Overexpression of Interleukin-15 Compromises CD4-Dependent Adaptive Immune Responses against Herpes Simplex Virus 2  Academic Article
• Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population  Academic Article
• Processing of Tumor Antigen Differentially Impacts the Development of Helper and Effector CD4+ T-cell Responses  Academic Article
• Protection by CD4 or CD8 T Cells against Pulmonary Mycobacterium bovis Bacillus Calmette-Guérin Infection  Academic Article
• Protein kinase A-catalyzed phosphorylation of heat shock protein 60 chaperone regulates its attachment to histone 2B in the T lymphocyte plasma membrane  Academic Article
• Radiation-Induced Lymphocyte Apoptosis to Predict Radiation Therapy Late Toxicity in Prostate Cancer Patients  Academic Article
• Recombinant Adenovirus Vaccines Can Successfully Elicit CD8+ T Cell Immunity under Conditions of Extreme Leukopenia  Academic Article
• Reduced amount of intestinal mucus by treatment with anti-CD4 antibody interferes with the spontaneous cure of Nippostrongylus brasiliensis-infection in mice  Academic Article
• Repeated Seasonal Influenza Vaccination: How Much Is Too Much of a Good Thing?  Academic Article
• Respiratory macrophages regulate CD4 T memory responses to mucosal immunization with recombinant adenovirus-based vaccines  Academic Article
• SARS-CoV-2 vaccination diversifies the CD4+ spike-reactive T cell repertoire in patients with prior SARS-CoV-2 infection  Academic Article
• Sensitization to Gliadin Induces Moderate Enteropathy and Insulitis in Nonobese Diabetic-DQ8 Mice  Academic Article
• Serotonin Activates Dendritic Cell Function in the Context of Gut Inflammation  Academic Article
• Severe mental illness at ART initiation is associated with worse retention in care among HIV-infected Ugandan adults  Academic Article
• Single Mucosal, but Not Parenteral, Immunization with Recombinant Adenoviral-Based Vaccine Provides Potent Protection from Pulmonary Tuberculosis  Academic Article
• Sputum T lymphocytes in asthma, COPD and healthy subjects have the phenotype of activated intraepithelial T cells (CD69+ CD103+)  Academic Article
• Survival of HIV-Infected Adolescents on Antiretroviral Therapy in Uganda: Findings from a Nationally Representative Cohort in Uganda  Academic Article
• T Cell Epitope Immunotherapy Induces a CD4+ T Cell Population with Regulatory Activity  Academic Article
• T Cell-Derived Suppressive Activity: Evidence of Autocrine Noncytolytic Control of HIV Type 1 Transcription and Replication  Academic Article
• T Lymphocyte Responses to Nonpolymorphic HLA-Derived Peptides Are Associated With Chronic Renal Allograft Dysfunction  Academic Article
• T-cell immunity generated by recombinant adenovirus vaccines  Academic Article
• T-cell-mediated inflammation does not contribute to the maintenance of airway dysfunction in mice  Academic Article
• The Absence or Overexpression of IL-15 Drastically Alters Breast Cancer Metastasis via Effects on NK Cells, CD4 T Cells, and Macrophages  Academic Article
• The Hayflick Limit May Determine the Effective Clonal Diversity of Naive T Cells  Academic Article
• The Myxoma Virus M-T4 Gene Encodes a Novel RDEL-Containing Protein That Is Retained within the Endoplasmic Reticulum and Is Important for the Productive Infection of Lymphocytes  Academic Article
• The Soluble Tachyzoite Antigen of Toxoplasma gondii Has a Protective Effect on Mouse Allografts  Academic Article
• The anti-idiotypic antibody 1F7 selectively inhibits cytotoxic T cells activated in HIV-1 infection  Academic Article
• The influence of lymphocyte counts and disease progression on circulating and inducible anti-HIV-1 cytotoxic T-cell activity in HIV-1-infected subjects  Academic Article
• The novel CD4+CD25+ regulatory T cell effector molecule fibrinogen-like protein 2 contributes to the outcome of murine fulminant viral hepatitis  Academic Article
• The potential of peptide immunotherapy in allergy and asthma  Academic Article
• Tn-MUC1 DC Vaccination of Rhesus Macaques and a Phase I/II Trial in Patients with Nonmetastatic Castrate-Resistant Prostate Cancer  Academic Article
• Tumor Protection Following Vaccination With Low Doses of Lentivirally Transduced DCs Expressing the Self-antigen erbB2  Academic Article
• T‐Cell Phenotypes Predictive of Frailty and Mortality in Elderly Nursing Home Residents  Academic Article
• Vaccination-Induced Autoimmune Vitiligo Is a Consequence of Secondary Trauma to the Skin  Academic Article
• Visceral pain perception is determined by the duration of colitis and associated neuropeptide expression in the mouse  Academic Article