selected scholarly activity
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chapters
- 41 Heparin-Induced Thrombocytopenia. 741-767. 2019
- Acquired Thrombocytopenia. 135-148. 2019
- Heparin-Induced Thrombocytopenia. 741-767. 2019
- Heparin-Induced Thrombocytopenia. 491-527. 2019
- If the Platelets Are Low, Is It HIT?. 455-479. 2019
- Chapter 132 Thrombocytopenia Caused by Platelet Destruction, Hypersplenism, or Hemodilution. 1955-1972. 2018
- Chapter 133 Heparin-Induced Thrombocytopenia. 1973-1983. 2018
- Heparin-Induced Thrombocytopenia. 1973-1983. 2018
- Thrombocytopenia Caused by Platelet Destruction, Hypersplenism, or Hemodilution. 1955-1972. 2018
- Heparin‐Induced Thrombocytopenia. 341-356. 2017
- Heparin-Induced Thrombocytopenia. 789-811. 2017
- Heparin-Induced Thrombocytopenia. 1973-1983. 2017
- Management of immune‐mediated thrombocytopenia. 245-264. 2016
- Laboratory Evaluation of Heparin‐Induced Thrombocytopenia. 174-191. 2013
- Heparin‐Induced Thrombocytopenia. 322-334. 2013
- 25 Heparin-Induced Thrombocytopenia. 442-473. 2013
- Chapter 42 Heparin-Induced Thrombocytopenia. 851-882. 2013
- Heparin-Induced Thrombocytopenia. 442-473. 2013
- Heparin-Induced Thrombocytopenia. 851-882. 2013
- Acquired Thrombocytopenia. 154-173. 2011
- Treatment of Heparin-Induced Thrombocytopenia. 269-288. 2009
- Management of Immune Thrombocytopenia. 344-375. 2009
- Diagnosis and Management of Heparin‐Induced Thrombocytopenia. 158-167. 2008
- Anticoagulants. 107-112. 2008
- Heparin-Induced Thrombocytopenia. 1344-1351. 2007
- Clinical Picture of Heparin-Induced Thrombocytopenia. 21-66. 2007
- Frequency of Heparin-Induced Thrombocytopenia. 67-116. 2007
- History of Heparin-Induced Thrombocytopenia. 1-20. 2007
- Laboratory Testing for Heparin-Induced Thrombocytopenia. 227-260. 2007
- Pseudo-Heparin-Induced Thrombocytopenia. 261-282. 2007
- Treatment of Heparin-Induced Thrombocytopenia: An Overview. 283-318. 2007
- CHAPTER 44 The Diagnosis and Management of Heparin-Induced Thrombocytopenia. 395-403. 2007
- Chapter 25 Heparin-Induced Thrombocytopenia. 421-445. 2007
- Contributing Authors. ix-xi. 2007
- Heparin-Induced Thrombocytopenia. 421-445. 2007
- The Diagnosis and Management of Heparin-Induced Thrombocytopenia. 395-403. 2007
- Heparin-induced thrombocytopenia. 179-221. 2006
- Chapter 24 Heparin-Induced Thrombocytopenia. 673-697. 2005
- Heparin-Induced Thrombocytopenia. 673-697. 2005
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conferences
- An evaluation of the clinical impacts of 7‐day platelets. Transfusion. 480-493. 2023
- Transfusion Reactions Following the Implementation of Seven Day Platelets. Transfusion. 256A-256A. 2020
- A case of cerebral venous sinus thrombosis (CVST) secondary to spontaneous heparin-induced thrombocytopenia (HIT). International Journal of Stroke. 15-15. 2019
- Autoimmune HIT due to apheresis catheter heparin flushes for stem cell harvesting before autotransplantation for myeloma. Blood. 1679-1682. 2017
- Analysis of Red Blood Cell Storage Duration and in-Hospital Mortality Using Time Dependent Exposure: Is the Oldest Blood Bad?. Transfusion. 33A-33A. 2017
- Informing Fresh Versus Old Red Cell Management (INFORM) Trial: A Large International Pragmatic Randomized Trial. Transfusion. 5A-5A. 2016
- Rivaroxaban for Treatment of Suspected or Confirmed Heparin-Induced Thrombocytopenia Study. Blood. 3468-3468. 2015
- Difficulties in Establishing the Cause of Thrombocytopenia Among Ambulatory Patients Referred to Hematology: An Agreement Study. Blood. 3521-3521. 2014
- lLow Level Platelet-Activating Antibodies in Patients Suspected of Having Heparin-Induced Thrombocytopenia but Testing Negative in the "Gold Standard" Functional Test. Blood. 2014
- Combination Of 4T’s Score and Rapid Gel Centrifugation Assay Excludes HIT In a Prospective Cohort Study. Blood. 3535-3535. 2013
- Serological investigation of 20 patients re-exposed to heparin with a previous history of heparin-induced thrombocytopenia (HIT). Journal of Thrombosis and Haemostasis. 132-132. 2013
- The clincal impact of anti-protamine/heparin antibodies in patients undergoing cardiac surgery. Journal of Thrombosis and Haemostasis. 412-412. 2013
- EPIDEMIOLOGY OF HEPARIN INDUCED THROMBOCYTOPENIA IN THE INTENSIVE CARE UNIT. Critical Care Medicine. U213-U213. 2012
- Heparin-Induced Thrombocytopenia In The ICU: ELISA Versus SRA Testing. A47. DIAGNOSTIC TECHNIQUES AND MONITORING. a1669-a1669. 2012
- The pathogenesis of warfarin-associated venous limb ischemia and gangrene complicating cancer: clinical and laboratory parallels with heparin-induced thrombocytopenia (HIT). Thrombosis Research. S159-S160. 2012
- What is the Utility of Two Different ELISAs and the 4T's Score in Determining the Probability of Heparin-Induced Thrombocytopenia Following Cardiac Surgery?. Circulation. 2011
- Identifying Drugs Implicated in Drug-Induced Immune Thrombocytopenia Using Levels of Evidence Applied to Laboratory Tests. Blood. 1421-1421. 2011
- Laboratory HIT Testing in Critically III Patients. Blood. 93-93. 2011
- 111 Pre-operative, intra-operative and post-operative factors associated with heparin induced thrombocytopenia post cardiac surgery. Canadian Journal of Cardiology. S103-S103. 2011
- Can We Do a 25,000 Patient Pragmatic Study to Address the Age of Blood and Mortality Controversy? A Pilot to Determine Feasibility. Transfusion. 193A-193A. 2011
- Utilizing Automation to Improve Blood Product Delivery to Patients. Transfusion. 267A-267A. 2011
- Arterial thromboembolectomy and intraoperative anticoagulation in the setting of heparin-induced thrombocytopenia (HIT). Journal of Thrombosis and Haemostasis. 333-334. 2011
- Fondaparinux treatment of acute heparin-induced thrombocytopenia (HIT) confirmed by a positive serotonin-release assay (SRA plus ). Journal of Thrombosis and Haemostasis. 267-267. 2011
- HIT paradigms and paradoxes. Journal of Thrombosis and Haemostasis. 253-253. 2011
- A RANDOMIZED, DOUBLE-BLIND STUDY TO ASSESS SERUM TRANSAMINASE ELEVATIONS AND ANTIBODY FORMATION FOLLOWING REPEAT SUBCUTANEOUS DOSING OF LMWH, UFH OR THE NOVEL ANTICOAGULANT M118 IN HEALTHY VOLUNTEERS.. Clinical Pharmacology and Therapeutics. S72-S72. 2011
- INTER-RATER VARIABILITY OF THE 4TS AND CHONG SCORE FOR HEPARIN INDUCED THROMBOCYTOPENIA. Critical Care Medicine. U207-U207. 2010
- Central Statistical Monitoring Of An International Thromboprophylaxis Trial. American Journal of Respiratory and Critical Care Medicine. 2010
- Inter-Rater Reliability of the 4Ts Scoring System for Diagnosing Heparin-Induced Thrombocytopenia in Critically III Patients. Blood. 1535-1535. 2009
- Impact of Just In Time (JIT) Delivery of Blood Products on the Crossmatch/Transfusion (C/T) Ratio. Transfusion. 268A-268A. 2009
- Laboratory Information System - The Key Enabler to Consolidating Transfusion Services. Transfusion. 303A-303A. 2009
- Managing bleeding in anticoagulated patients with a focus on novel therapeutic agents. Journal of Thrombosis and Haemostasis. 107-110. 2009
- A Prospective Multicenter Cohort Study On Heparin-induced Thrombocytopenia In Acute Ischemic Stroke Patients. Stroke. E156-E156. 2009
- Incidence of HPA-9b in Testing for Neonatal Alloimmune Thrombocytopenia.. Blood. 3214-3214. 2007
- An algorithm for "indeterminate" test results in the platelet serotonin release assay for heparin-induced thrombocytopenia (HIT).. Blood. 312A-312A. 2006
- Efficacy of prothrombin complex (PCC) for reversal of warfarin effect.. Blood. 288A-288A. 2006
- Platelet-activating anti-platelet factor 4/polyanion antibodies without preceding heparin therapy: A transient autoimmune disorder resembling heparin-induced thrombocytopenia ("spontaneous HIT").. Blood. 311A-312A. 2006
- HIT: Lessons Learned. Pathophysiology of Haemostasis and Thrombosis: international journal on haemostasis and thrombosis research. 50-57. 2006
- Towards a conceptual framework for diagnosis of heparin-induced thrombocytopenia (HIT). Blood. 359A-359A. 2005
- Argatroban Inhibits Human Factor Xa at Therapeutic Drug Levels: An Explanation for Its Prolongation of the INR.. Blood. 1845-1845. 2004
- Laboratory testing for HIT antibodies: How much class do we need?. Blood. 825A-826A. 2004
- Comparison of heparin-induced thrombocytopenia antibody (HIT-Ab) generation and in vitro cross-reactivity after elective hip or knee replacement surgery in patients receiving Antithrombotic prophylaxis with fondaparinux or enoxaparin.. Blood. 164A-164A. 2003
- Effect of fondaparinux on platelet activation in the presence of heparin-dependent anti-platelet antibodies. A blinded comparative multicenter study with unfractionated heparin.. Blood. 319A-319A. 2003
- Preliminary evaluation of a clinical scoring system for estimating the pretest probability of heparin-induced thrombocytopenia: The "4 T's".. Blood. 535A-535A. 2003
- Subclass analysis of Anti-Ib/IX autoantibodies in patients with idiopathic thrombocytopenic purpura.. Blood. 294A-295A. 2003
- Phase 1 results from a transfusion committee research project: The status of transfusion committees in Ontario hospitals. Transfusion. 167A-167A. 2003
- Severe hypotension following transfusion of pre-storage leukoreduced red blood cells and acute normovolemic hemodilution whole blood. Transfusion. 112A-112A. 2003
- Agreements Between the Prothrombin Times of Blood Treated In Vitro with Heparinase During Cardiopulmonary Bypass (CPB) and Blood Sampled After CPB and Systemic Protamine. Anesthesia and Analgesia. 15-20. 2003
- Gender and risk of immune heparin-induced thrombocytopenia (HIT).. Blood. 17A-17A. 2002
- Genetic polymorphisms in the noncoding sequences of the PF4 and PF4alt genes are not associated with the development of heparin-induced thrombocytopenia.. Blood. 687A-687A. 2002
- Immunization to platelet alloantigens: A ten-year retrospective study.. Blood. 482A-483A. 2002
- Platelet count monitoring and laboratory testing for heparin-induced thrombocytopenia - Recommendations of the College of American Pathologists. Archives of Pathology and Laboratory Medicine. 1415-1423. 2002
- A novel universal antigen capture assay to measure platelet-bound autoantibodies in immune thrombocytopenic purpura.. Blood. 520A-520A. 2001
- Effect of splenectomy in patients with chronic idiopathic thrombocytopenic purpura.. Blood. 524A-524A. 2001
- Subclass distribution of platelet bound anti-GPIIbIIIa autoantibodies in immune thrombocytopenic purpura.. Blood. 522A-522A. 2001
- Ten-year follow-up of von Willebrand factor (vWF) multimers in two patients with bleeding gastrointestinal (GI) angiodysplasias and aortic stenosis with long-term cessation of bleeding following aortic valve replacement: A novel bleeding syndrome of surgically-reversible acquired von Willebrand's syndrome (vWS-2A).. Blood. 262A-262A. 2001
- Trafficking of autoantibodies in platelets from ITP patients: Investigation using glycoprotein-specific assays.. Blood. 521A-521A. 2001
- Decreased von Willebrand factor proteolytic activity associated with thrombocytopenic disorders.. Blood. 531A-531A. 2000
- Evaluation of platelet morphology and the subcellular distribution of PAIgG in patients with ITP and non-immune thrombocytopenia.. Blood. 249A-249A. 2000
- Expression of CD109 with alternate forms of membrane anchoring unique to platelets and megakaryocytic cell lines.. Blood. 55B-55B. 2000
- In vitro time-dependent changes of surface PAIgG in ITP and non-immune thrombocytopenia.. Blood. 65B-65B. 2000
- Possible pathways of IgG trafficking in platelets.. Blood. 250A-250A. 2000
- The impact of idiopathic thrombocytopenic purpura in pregnancy.. Blood. 248A-248A. 2000
- Transience of heparin-induced thrombocytopenia antibodies.. Blood. 531A-531A. 2000
- Treatment of chronic refractory idiopathic thrombocytopenic purpura with cyclophosphamide and cyclosporine.. Blood. 253A-253A. 2000
- Heparin-induced thrombocytopenia and its treatment.. Journal of Thrombosis and Thrombolysis. 29-35. 2000
- Heparin-induced thrombocytopenia.. Clinical Laboratory. 195-197. 2000
- Morphological investigation of microparticle generation in heparin-induced throbocytopenia using confocal microscope and electron microscopy.. Blood. 16A-16A. 1999
- Proteolysis of human platelet FcRIIa during activation induced by heparin-induced thrombocytopenia (HIT) sera.. Blood. 442A-442A. 1999
- Venous limb gangrene (VLG) complicating warfarin treatment of deep-vein thrombosis (DVT) ln metastatic carcinoma.. Blood. 114B-114B. 1999
- Importance of patient population in the frequency of HIT: A comparison of activation and antigen assays. Thrombosis and Haemostasis. 363-364. 1999
- 'Incidental' unfractionated heparin (UFH) vs normal saline (NS) flushes for intraoperative invasive catheters and the frequency of formation of heparin-induced thrombocytopenia IgG antibodies (HIT-IgG): A randomized, controlled trial.. Blood. 91B-91B. 1998
- Frequency of upper limb deep venous thrombosis (UL-DVT) in relation to central venous catheter (CVC) use in patients with heparin-induced thrombocytopenia (HIT): Evidence for interaction of systemic (HIT) and local (CVC) prothrombotic risk factors.. Blood. 500A-501A. 1998
- Timing of heparin-induced thrombocytopenia (HIT) in relation to previous heparin use: Absence of an anamnestic immune response, and implications for repeat heparin use in patients with a history of HIT.. Blood. 182A-182A. 1998
- Clinical presentation of heparin-induced thrombocytopenia. Seminars in Hematology. 9-16. 1998
- Diagnosis of heparin-induced thrombocytopenia (HIT): Comparison of methods.. Transfusion. 98S-98S. 1998
- Limitations of conventional treatment options for heparin-induced thrombocytopenia. Seminars in Hematology. 17-25. 1998
- A prospective study of antigen capture assays for the investigation of idiopathic thrombocytopenic purpura (ITP).. Blood. 2037-2037. 1997
- Measurement of endogenous and exogenous alpha granular platelet proteins in patients with immune and nonimmune thrombocytopenia.. Blood. 2040-2040. 1997
- Persistence of anti-glycoprotein IIb/IIIa antibodies in patients in complete remission from idiopathic thrombocytopenic purpura (ITP).. Blood. 2038-2038. 1997
- Sequestration of the Gov alloantigens into low density high molecular weight membrane fractions isolated from human platelets.. Blood. 3029-3029. 1997
- Factor V Leiden and thrombotic complications in heparin-induced thrombocytopenia. Thrombosis and Haemostasis. P1287-P1287. 1997
- Heparin-induced thrombocytopenia, heparin-induced skin lesions, and arterial thrombosis. Thrombosis and Haemostasis. P2301-P2301. 1997
- Maternal alloimmunization to the Gov(a)/Gov(b) antigens on human platelets.. Blood. 1271-1271. 1996
- Measurement of platelet procoagulant activity in heparin induced thrombocytopenia.. Blood. 3011-3011. 1996
- FC(gamma)IIA receptor genotype heterogeneity and platelet activation by heparin-induced thrombocytopenia IgG (HIT-IgG): A possible explanation for the predominance of the ''low responder'' (his(131)) Fc(gamma)IIA receptor genotype in HIT patients.. Blood. 2136-2136. 1995
- Formation of heparin-induced thrombocytopenia IgG (HIT-IgG) without thrombocytopenia: Analysis of a clinical trial.. Blood. 2137-2137. 1995
- Isolation and characterization of cysteine protease in thrombotic thrombocytopenic purpura.. Blood. 1134-1134. 1995
- Lightning strikes twice: Glanzmann's thrombasthenia in two half-sisters.. Blood. 3576-3576. 1995
- Splenectomy reduces the frequency of relapse in patients with chronic relapsing TTP.. Blood. 343-343. 1995
- VENOUS LIMB GANGRENE COMPLICATING HEPARIN-INDUCED THROMBOCYTOPENIA - IMPLICATIONS FOR TRANSFUSION MEDICINE. Transfusion. S97-S97. 1995
- WARFARIN TREATMENT OF DEEP-VEIN THROMBOSIS COMPLICATING HEPARIN-INDUCED THROMBOCYTOPENIA (HIT) IS A RISK FACTOR FOR INITIATION OF VENOUS LIMB GANGRENE - REPORT OF 9 PATIENTS IMPLICATING THE INTERACTING PROCOAGULANT EFFECTS OF 2 ANTICOAGULANT AGENTS. Thrombosis and Haemostasis. 1110-1110. 1995
- A PROSPECTIVE-STUDY OF HEPARIN-INDUCED THROMBOCYTOPENIA - UNFRACTIONATED HEPARIN COMPARED WITH LOW-MOLECULAR-WEIGHT HEPARIN. Blood. A188-A188. 1994
- DETECTION OF PLATELET-ASSOCIATED AUTOANTIBODIES TO THE GP-IIB/IIIA COMPLEX BY DIRECT RADIOIMMUNO-PRECIPITATION - A SPECIFIC TEST FOR IDIOPATHIC THROMBOCYTOPENIC PURPURA. Blood. A185-A185. 1994
- EVALUATION OF THE FC RECEPTOR IIA GENOTYPE FREQUENCIES AMONG PATIENTS WITH HEPARIN-INDUCED THROMBOCYTOPENIA. Blood. A661-A661. 1994
- GENERATION OF PLATELET-DERIVED MICROPARTICLES AND PROCOAGULANT ACTIVITY BY IGG PLATELET AGONISTS - COMPARISON WITH STANDARD PLATELET AGONISTS. Blood. A528-A528. 1994
- HEPARIN-INDUCED THROMBOCYTOPENIA - PREDOMINANCE OF VENOUS THROMBOTIC COMPLICATIONS, AND A HIGH-RISK FOR SUBSEQUENT THROMBOSIS IN PATIENTS WHO ARE INITIALLY RECOGNIZED WITH ISOLATED THROMBOCYTOPENIA. Blood. A188-A188. 1994
- HETEROGENEITY OF THE MEMBRANE ANCHOR FOR GP175 EXPRESSING THE GOV ALLOANTIGEN SYSTEM. Blood. A472-A472. 1994
- THE DEVELOPMENT AND EVALUATION OF A NOVEL TEST FOR HEPARIN-INDUCED THROMBOCYTOPENIA. Blood. A188-A188. 1994
- THE ROLE OF PLATELET ALLOANTIGEN GENOTYPING AND VNTR ANALYSIS USING DNA-DERIVED FROM AMNIOTIC-FLUID IN THE MANAGEMENT OF NEONATAL ALLOIMMUNE THROMBOCYTOPENIA. Blood. A527-A527. 1994
- BIOCHEMICAL-CHARACTERIZATION OF THE GOV ALLOANTIGEN ON HUMAN PLATELETS AND CELL-LINES. Blood. A269-A269. 1993
- CHARACTERIZATION OF MULTIMERIN EXPRESSION ON PLATELETS ACTIVATED IN-VITRO AND IN-VIVO. Blood. A158-A158. 1993
- CIRCULATING PLATELET-DERIVED MICROPARTICLES IN PATIENTS WITH HEPARIN-INDUCED THROMBOCYTOPENIA. Blood. A335-A335. 1993
- IGG FROM PATIENTS WITH HEPARIN-INDUCED THROMBOCYTOPENIA (HIT) BINDS TO A PF4/HEPARIN COMPLEX AND NOT TO HEPARIN ALONE. Blood. A335-A335. 1993
- HEPARIN-INDUCED THROMBOCYTOPENIA IS MORE COMMON WITH UNFRACTIONATED HEPARIN THAN WITH LOW-MOLECULAR-WEIGHT HEPARIN. Thrombosis and Haemostasis. 911-911. 1993
- PLATELET-DERIVED MICROPARTICLES ARE FOUND IN-VIVO IN PATIENTS WITH HEPARIN-INDUCED THROMBOCYTOPENIA (HIT). Thrombosis and Haemostasis. 912-912. 1993
- TRANSIENT GLOBAL AMNESIA FOLLOWING INTRAVENOUS HEPARIN BOLUS THERAPY IS CAUSED BY HEPARIN-INDUCED THROMBOCYTOPENIA. Thrombosis and Haemostasis. 911-911. 1993
- DETERMINANTS OF PLATELET DONOR VARIABILITY IN DIAGNOSTIC TESTING FOR HEPARIN-INDUCED THROMBOCYTOPENIA. Thrombosis and Haemostasis. 1036-1036. 1991
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journal articles
- Antibody Fingerprints Linking Adenoviral Anti-PF4 Disorders. New England Journal of Medicine. 390:1827-1829. 2024
- Rescue Therapy in Chronic Prothrombotic Autoimmune Anti-PF4 Disorder. New England Journal of Medicine. 389:1339-1341. 2023
- Acute thrombocytopenia suggesting thrombotic microangiopathy. American Journal of Hematology. 97:659-665. 2022
- Platelet-activating anti-PF4 antibodies mimic VITT antibodies in an unvaccinated patient with monoclonal gammopathy. Haematologica. 107:1219-1221. 2022
- Post-cardiac surgery thrombotic thrombocytopenic purpura: presence of anti-ADAMTS13 autoantibodies at preoperative baseline. Platelets. 33:479-483. 2022
- Laboratory testing for VITT antibodies. Seminars in Hematology. 59:80-88. 2022
- Platelet-activating anti-PF4 disorders: An overview. Seminars in Hematology. 59:59-71. 2022
- The Epidemiology of Thrombosis With Thrombocytopenia Syndrome: Analogies With Heparin-Induced Thrombocytopenia. ACP journal club. 175:604-605. 2022
- Treatment of vaccine-induced immune thrombotic thrombocytopenia (VITT). Seminars in Hematology. 59:89-96. 2022
- Vaccine-induced immune thrombotic thrombocytopenia (VITT). Seminars in Hematology. 59:57-58. 2022
- Heterogeneity of Vaccine-Induced Immune Thrombotic Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination and Safety of Second Vaccination with BNT162b2. Thrombosis and Haemostasis. 122:304-307. 2022
- Therapeutic strategies in patients with coagulopathy and disseminated intravascular coagulation: awareness of the phase-dependent characteristics. Minerva Medicolegale. 112:701-712. 2022
- Vaccine‐induced immune thrombotic thrombocytopenia (VITT) ‐ update on diagnosis and management considering different resources: Response to Comment from Yamada et al. Journal of Thrombosis and Haemostasis. 20:542-543. 2022
- Recognizing Vaccine-Induced Immune Thrombotic Thrombocytopenia. Critical Care Medicine. 50:e80-e86. 2022
- The authors reply. Critical Care Medicine. 50:e94-e95. 2022
- Vaccine‐induced immune thrombotic thrombocytopenia (VITT): Update on diagnosis and management considering different resources. Journal of Thrombosis and Haemostasis. 20:149-156. 2022
- Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia. Blood. 138:2256-2268. 2021
- Heparin-Induced Thrombocytopenia and Vaccine-Induced Immune Thrombotic Thrombocytopenia Antibodies: Fraternal—Not Identical—Twins. Thrombosis and Haemostasis. 121:1558-1561. 2021
- Spontaneous Heparin-Induced Thrombocytopenia Presenting as Cerebral Venous Sinus Thrombosis. Neurology: Clinical Practice. 11:e929-e931. 2021
- Venous Thromboembolism and Mild Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination. Thrombosis and Haemostasis. 121:1677-1680. 2021
- Heparin induced thrombocytopenia in relation to SARS-CoV-2 infection and ABO blood group. Thrombosis Research. 207:62-65. 2021
- VIPIT versus VITT: what's in a name?. Thrombosis Research. 207:158-160. 2021
- Anti–platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein. Blood. 138:1269-1277. 2021
- Cerebral venous sinus thrombosis associated with spontaneous heparin-induced thrombocytopenia syndrome after total knee arthroplasty. Platelets. 32:936-940. 2021
- Double high-dose immunoglobulin for ChAdOx1 nCov-19 vaccine-induced immune thrombotic thrombocytopenia. Thrombosis Research. 206:14-17. 2021
- Adjunct Immune Globulin for Vaccine-Induced Immune Thrombotic Thrombocytopenia. New England Journal of Medicine. 385:720-728. 2021
- Catastrophic antiphospholipid syndrome refractory to high-dose intravenous immunoglobulin responsive to therapeutic plasma exchange. Platelets. 32:828-831. 2021
- Managing thrombosis and cardiovascular complications of COVID-19: answering the questions in COVID-19-associated coagulopathy. Expert Review of Respiratory Medicine. 15:1003-1011. 2021
- Spontaneous HIT syndrome: Knee replacement, infection, and parallels with vaccine-induced immune thrombotic thrombocytopenia. Thrombosis Research. 204:40-51. 2021
- Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2. Blood. 138:299-303. 2021
- Thrombotic Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination. New England Journal of Medicine. 385:e11. 2021
- Thrombocytopénie induite par l’héparine. CANADIAN MEDICAL ASSOCIATION JOURNAL. 193:E1067-E1068. 2021
- Anemia-Induced Bleeding in Patients with Platelet Disorders. Transfusion Medicine Reviews. 35:22-28. 2021
- Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination. New England Journal of Medicine. 384:2092-2101. 2021
- Heparin-induced thrombocytopenia. CANADIAN MEDICAL ASSOCIATION JOURNAL. 193:E736-E736. 2021
- A comparative study of platelet factor 4‐enhanced platelet activation assays for the diagnosis of heparin‐induced thrombocytopenia. Journal of Thrombosis and Haemostasis. 19:1096-1102. 2021
- Symmetrical peripheral gangrene in critical illness. Transfusion and Apheresis Science. 60:103094-103094. 2021
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Serotonin‐release assay‐positive but platelet factor 4‐dependent enzyme‐immunoassay negative:
HIT or notHIT ?. American Journal of Hematology. 96:320-329. 2021 - Proposal of the Definition for COVID-19-Associated Coagulopathy. Journal of Clinical Medicine. 10:191-191. 2021
- Proposal of the Definition for COVID-19-Associated Coagulopathy 2021
- COVID-19 versus HIT hypercoagulability. Thrombosis Research. 196:38-51. 2020
- The unique characteristics of COVID-19 coagulopathy. Critical Care. 24:360. 2020
- Genome-Wide Association Study Identifies Variation in ABO As Risk Factor for Platelet Reactivity in Heparin-Induced Thrombocytopenia. Blood. 136:38-39. 2020
- Challenges in Detecting Clinically Relevant Heparin-Induced Thrombocytopenia Antibodies. Hamostaseologie. 40:472-484. 2020
- Management of heparin-induced thrombocytopenia: systematic reviews and meta-analyses. Blood Advances. 4:5184-5193. 2020
- Colloid Transfusion, Natural Anticoagulant Depletion, and Symmetric Peripheral Gangrene. New England Journal of Medicine. 383:1592-1594. 2020
- ISTH DIC subcommittee communication on anticoagulation in COVID‐19. Journal of Thrombosis and Haemostasis. 18:2138-2144. 2020
- Limitations of the particle immunofiltration assay test for diagnosis of heparin‐induced thrombocytopenia. American Journal of Hematology. 95:E250-E254. 2020
- High‐dose IVIG plus cangrelor platelet “anesthesia” during urgent heparin‐CPB in a patient with recent SRA‐negative HIT‐thrombosis with persisting platelet‐activating antibodies. Research and Practice in Thrombosis and Haemostasis. 4:1060-1064. 2020
- Maximum 24‐hour platelet count fall: Metric for improving the diagnosis of heparin‐induced thrombocytopenia among patients with intermediate probability 4Ts scores. Journal of Thrombosis and Haemostasis. 18:2018-2024. 2020
- Combination of two complementary automated rapid assays for diagnosis of heparin‐induced thrombocytopenia (HIT). Journal of Thrombosis and Haemostasis. 18:1435-1446. 2020
- RE: The prothrombin time ratio is not a more effective marker for evaluating sepsis‐induced coagulopathy than fibrin‐related markers: Response to the Letter‐to‐the‐Editor by Dr Wada. Journal of Thrombosis and Haemostasis. 18:1507-1509. 2020
- Venous limb gangrene and pulseless electrical activity (PEA) cardiac arrest during management of deep‐vein thrombosis and progressive limb ischemic necrosis following vascular surgery. American Journal of Hematology. 95:712-717. 2020
- HIT: still stringing us along. Blood. 135:1193-1194. 2020
- A practical approach to evaluating postoperative thrombocytopenia. Blood Advances. 4:776-783. 2020
- Fondaparinux cross-reactivity in heparin-induced thrombocytopenia successfully treated with high-dose intravenous immunoglobulin and rivaroxaban. Platelets. 31:124-127. 2020
- Serotonin‐release assay‐negative heparin‐induced thrombocytopenia. American Journal of Hematology. 95:38-47. 2020
- Spontaneous heparin-induced thrombocytopenia syndrome presenting as bilateral adrenal infarction after knee arthroplasty. BMJ Case Reports. 12:e232769-e232769. 2019
- Diagnosis and management of sepsis‐induced coagulopathy and disseminated intravascular coagulation. Journal of Thrombosis and Haemostasis. 17:1989-1994. 2019
- Ischemic limb necrosis in septic shock: What is the role of high‐dose vasopressor therapy?. Journal of Thrombosis and Haemostasis. 17:1973-1978. 2019
- High-dose intravenous immunoglobulin for the treatment and prevention of heparin-induced thrombocytopenia: a review. Expert Review of Hematology. 12:685-698. 2019
- Proposal of a two‐step process for the diagnosis of sepsis‐induced disseminated intravascular coagulation. Journal of Thrombosis and Haemostasis. 17:1265-1268. 2019
- Timeline of heparin‐induced thrombocytopenia seroconversion in serial plasma samples tested using an automated latex immunoturbidimetric assay. International Journal of Laboratory Hematology. 41:493-502. 2019
- Autoimmune heparin‐induced thrombocytopenia and venous limb gangrene after aortic dissection repair: in vitro and in vivo effects of intravenous immunoglobulin. Transfusion. 59:1924-1933. 2019
- Neutrophil and Monocyte Counts in Heparin-Induced Thrombocytopenia. Thrombosis and Haemostasis. 119:941-951. 2019
- The association between platelet transfusions and mortality in patients with critical illness. Transfusion. 59:1962-1970. 2019
- Advance in the Management of Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation. Journal of Clinical Medicine. 8:728-728. 2019
- High‐dose intravenous immunoglobulin to treat spontaneous heparin‐induced thrombocytopenia syndrome. Journal of Thrombosis and Haemostasis. 17:841-844. 2019
- Laboratory diagnosis of heparin‐induced thrombocytopenia. International Journal of Laboratory Hematology. 41:15-25. 2019
- An international external quality assessment for laboratory diagnosis of heparin‐induced thrombocytopenia. Journal of Thrombosis and Haemostasis. 17:525-531. 2019
- Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT. Blood. 133:978-989. 2019
- Differential diagnoses for sepsis‐induced disseminated intravascular coagulation: communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis. 17:415-419. 2019
- Microvascular Thrombosis and Ischaemic Limb Losses in Critically Ill Patients. Hamostaseologie. 39:006-019. 2019
- Natural, not immune; classical, not alternative. Blood. 132:2421-2422. 2018
- Concurrence of symmetrical peripheral gangrene and venous limb gangrene following polytrauma: a case report. Journal of Medical Case Reports. 12:131. 2018
- American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia. Blood Advances. 2:3360-3392. 2018
- Heparin‐induced thrombocytopenia‐associated thrombosis: from arterial to venous to venous limb gangrene. Journal of Thrombosis and Haemostasis. 16:2128-2132. 2018
- Neutropenia and monocytopenia in recurrent anaphylactoid reactions after red blood cell transfusions in a woman with immunoglobulin A (IgA) deficiency and anti‐IgA. Transfusion. 58:2320-2325. 2018
- Systematic review of fondaparinux for heparin‐induced thrombocytopenia: When there are no randomized controlled trials. Research and Practice in Thrombosis and Haemostasis. 2:678-683. 2018
- High sensitivity and specificity of an automated IgG-specific chemiluminescence immunoassay for diagnosis of HIT. Blood. 132:1345-1349. 2018
- Acute haemolysis, DIC and renal failure after transfusion of uncross‐matched blood during trauma resuscitation: illustrative case and literature review. Transfusion Medicine. 28:319-325. 2018
- Cellular immune responses to platelet factor 4 and heparin complexes in patients with heparin‐induced thrombocytopenia. Journal of Thrombosis and Haemostasis. 16:1402-1412. 2018
- Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay. Chest. 153:1396-1404. 2018
- Intravenous Immune Globulin to Prevent Heparin-Induced Thrombocytopenia. New England Journal of Medicine. 378:1845-1848. 2018
- Levofloxacin-Induced Acute Immune-Mediated Thrombocytopenia of Rapid-Onset. Journal of Pharmacy Practice. 31:234-237. 2018
- Symmetrical Peripheral Gangrene: Mechanisms for Limb Loss in the ICU in Patients With Retained Pulses. Clinical Pulmonary Medicine. 25:61-66. 2018
- Apixaban for treatment of confirmed heparin-induced thrombocytopenia: a case report and review of literature. Experimental Hematology and Oncology. 6:21. 2017
- Autoimmune heparin‐induced thrombocytopenia. Journal of Thrombosis and Haemostasis. 15:2099-2114. 2017
- Fondaparinux for Treatment of Heparin-Induced Thrombocytopenia. Journal of the American College of Cardiology. 70:2649-2651. 2017
- Red blood cell storage and in-hospital mortality: a secondary analysis of the INFORM randomised controlled trial. The Lancet Haematology. 4:e544-e552. 2017
- IV Immunoglobulin for Autoimmune Heparin-Induced Thrombocytopenia. Chest. 152:453-455. 2017
- Direct oral anticoagulants for treatment of HIT: update of Hamilton experience and literature review. Blood. 130:1104-1113. 2017
- Spontaneous HIT syndrome post-knee replacement surgery with delayed recovery of thrombocytopenia: a case report and literature review. Platelets. 28:614-620. 2017
- Clinical effectiveness of a Bayesian algorithm for the diagnosis and management of heparin‐induced thrombocytopenia. Journal of Thrombosis and Haemostasis. 15:1640-1645. 2017
- Diagnostic accuracy of IgG‐specific versus polyspecific enzyme‐linked immunoassays in heparin‐induced thrombocytopenia: a systematic review and meta‐analysis. Journal of Thrombosis and Haemostasis. 15:1203-1212. 2017
- Performance characteristics of an automated latex immunoturbidimetric assay [HemosIL ® HIT-Ab (PF4-H) ] for the diagnosis of immune heparin-induced thrombocytopenia. Thrombosis Research. 153:108-117. 2017
- How do we approach thrombocytopenia in critically ill patients?. British Journal of Haematology. 177:27-38. 2017
- Sepsis and persisting neutropenia in a drug addict. American Journal of Hematology. 92:312-316. 2017
- Platelet count recovery and seroreversion in immune HIT despite continuation of heparin: further observations and literature review. Thrombosis and Haemostasis. 117:1868-1874. 2017
- Effect of Short-Term vs. Long-Term Blood Storage on Mortality after Transfusion. New England Journal of Medicine. 375:1937-1945. 2016
- Shock, acute disseminated intravascular coagulation, and microvascular thrombosis: is ‘shock liver’ the unrecognized provocateur of ischemic limb necrosis: reply. Journal of Thrombosis and Haemostasis. 14:2317-2319. 2016
- B cells, PF4/heparin complexes, and complement. Blood. 128:1781-1782. 2016
- Acute intraoperative HIT during heart surgery: Why so rare?. Thrombosis Research. 146:110-112. 2016
- Clinical picture of heparin-induced thrombocytopenia (HIT) and its differentiation from non-HIT thrombocytopenia. Thrombosis and Haemostasis. 116:813-822. 2016
- Heparin-induced thrombocytopenia in 2017 and beyond. Thrombosis and Haemostasis. 116:781-782. 2016
- Letter of response to Peters and Vlaar commentary. Transfusion. 56:2395-2397. 2016
- Management of heparin-induced thrombocytopenia. Current Opinion in Hematology. 23:462-470. 2016
- Platelet Activation Testing for Heparin-Induced Thrombocytopenia Antibodies. Chest. 150:478-480. 2016
- Protamine (heparin)‐induced thrombocytopenia: a review of the serological and clinical features associated with anti‐protamine/heparin antibodies. Journal of Thrombosis and Haemostasis. 14:1685-1695. 2016
- Difficulties in establishing the diagnosis of immune thrombocytopenia: An agreement study. American Journal of Hematology. 91:E327-E329. 2016
- Safe bridging to warfarin in heparin-induced thrombocytopenia. Thrombosis Research. 144:226-228. 2016
- How I treat patients with a history of heparin-induced thrombocytopenia. Blood. 128:348-359. 2016
- Rivaroxaban for treatment of suspected or confirmed heparin‐induced thrombocytopenia study. Journal of Thrombosis and Haemostasis. 14:1206-1210. 2016
- Demand on-demand testing for the diagnosis of heparin-induced thrombocytopenia. Thrombosis Research. 140:163-164. 2016
- Knee replacement and HIT without heparin. Blood. 127:961-962. 2016
- Shock, acute disseminated intravascular coagulation, and microvascular thrombosis: is ‘shock liver’ the unrecognized provocateur of ischemic limb necrosis?. Journal of Thrombosis and Haemostasis. 14:231-235. 2016
- Rationale and Design of the Informing Fresh versus Old Red Cell Management (INFORM) Trial: An International Pragmatic Randomized Trial. Transfusion Medicine Reviews. 30:25-29. 2016
- Thrombin generation, ProC(®)Global, prothrombin time and activated partial thromboplastin time in thawed plasma stored for seven days and after methylene blue/light pathogen inactivation.. Blood Transfusion. 14:66-72. 2016
- Ischemic Limb Gangrene with Pulses. New England Journal of Medicine. 373:2385-2388. 2015
- Heparin-induced thrombocytopenia. Current Opinion in Critical Care. 21:576-585. 2015
- Distinguishing between anti–platelet factor 4/heparin antibodies that can and cannot cause heparin‐induced thrombocytopenia. Journal of Thrombosis and Haemostasis. 13:1900-1907. 2015
- Progressive, Fatal Thrombosis Associated With Heparin-Induced Thrombocytopenia After Cardiac Surgery Despite “Therapeutic” Anticoagulation With Argatroban: Potential Role for PTT and ACT Confounding. Journal of Cardiothoracic and Vascular Anesthesia. 29:1319-1321. 2015
- Ischemic Limb Gangrene with Pulses. New England Journal of Medicine. 373:642-655. 2015
- Non–injection‐site necrotic skin lesions complicating postoperative heparin thromboprophylaxis. American Journal of Hematology. 90:747-750. 2015
- Combination of 4Ts score and PF4/H-PaGIA for diagnosis and management of heparin-induced thrombocytopenia: prospective cohort study. Blood. 126:597-603. 2015
- Warfarin-induced venous limb ischemia/gangrene complicating cancer: a novel and clinically distinct syndrome. Blood. 126:486-493. 2015
- Pitfalls in the diagnosis of heparin‐Induced thrombocytopenia: A 6‐year experience from a reference laboratory. American Journal of Hematology. 90:629-633. 2015
- The Role for Optical Density in Heparin-Induced Thrombocytopenia. Chest. 148:55-61. 2015
- The platelet serotonin‐release assay. American Journal of Hematology. 90:564-572. 2015
- Scoring systems for heparin-induced thrombocytopenia (HIT): Whither now?. Thrombosis and Haemostasis. 113:437-438. 2015
- The transfusion‐related acute lung injury controversy: lessons from heparin‐induced thrombocytopenia. Transfusion. 55:1128-1134. 2015
- 4Ts scoring with hemofiltration or hemodialysis clotting. Journal of Clinical Monitoring and Computing. 29:7-9. 2015
- Failure of Anticoagulant Thromboprophylaxis. Critical Care Medicine. 43:401-410. 2015
- Heparin-Induced Thrombocytopenia in Critically Ill Patients. Seminars in Thrombosis and Hemostasis. 41:049-060. 2015
- Heparin-Induced Thrombocytopenia Presenting as Bilateral Adrenal Hemorrhages. New England Journal of Medicine. 372:492-494. 2015
- Plasma exchange to remove HIT antibodies: dissociation between enzyme-immunoassay and platelet activation test reactivities. Blood. 125:195-198. 2015
- Prevalence and clinical implications of anti-PF4/heparin antibodies in intensive care patients: a prospective observational study. Journal of Thrombosis and Thrombolysis. 39:60-67. 2015
- Rivaroxaban for treatment of HIT: A riveting first experience. Thrombosis Research. 135:1-2. 2015
- Low Level Platelet-Activating Antibodies in Patients Suspected of Having Heparin-Induced Thrombocytopenia but Testing Negative in the ”Gold Standard” Functional Test. Blood. 124:2757-2757. 2014
- Design of the rivaroxaban for heparin-induced thrombocytopenia study. Journal of Thrombosis and Thrombolysis. 38:485-492. 2014
- Immature Platelet Count. Journal of the American College of Cardiology. 64:2130-2132. 2014
- Progressive thrombocytopenia after cardiac surgery in a 67-year-old man. CANADIAN MEDICAL ASSOCIATION JOURNAL. 186:929-933. 2014
- Voting with your fondaparinux. Thrombosis Research. 134:3-4. 2014
- Spontaneous heparin-induced thrombocytopenia syndrome: 2 new cases and a proposal for defining this disorder. Blood. 123:3651-3654. 2014
- An Instrument-based Immunoassay with an Appropriate Normal Range: Minimizing HIT Overdiagnosis. Thrombosis Research. 133:961-962. 2014
- Heparin-induced thrombocytopenia in the critically ill: Interpreting the 4Ts test in a randomized trial. Journal of Critical Care. 29:470.e7-470.e15. 2014
- Platelet Microparticle Generation Assay for Detection of HIT Antibodies: Advance, Retreat, or Too Soon to Tell?. Thrombosis Research. 133:957-958. 2014
- Serological investigation of patients with a previous history of heparin-induced thrombocytopenia who are reexposed to heparin. Blood. 123:2485-2493. 2014
- Anticoagulant failure in coagulopathic patients: PTT confounding and other pitfalls. Expert Opinion on Drug Safety. 13:25-43. 2014
- HIT complicating fondaparinux prophylaxis: fondaparinux-dependent platelet activation as a marker for fondaparinux- induced HIT. Thrombosis and Haemostasis. 112:1319-1322. 2014
- Spontaneous Heparin-Induced Thrombocytopenia Syndrome: Two New Cases and a Proposal For Defining This Disorder. Blood. 122:2328-2328. 2013
- Improving Clinical Interpretation of the Anti-Platelet Factor 4/Heparin Enzyme-Linked Immunosorbent Assay for the Diagnosis of Heparin-Induced Thrombocytopenia Through the Use of Receiver Operating Characteristic Analysis, Stratum-Specific Likelihood Ratios, and Bayes Theorem. Chest. 144:1269-1275. 2013
- Thrombocytopenia in Critically Ill Patients Receiving Thromboprophylaxis. Chest. 144:1207-1215. 2013
- Heparin-Induced Thrombocytopenia in Medical Surgical Critical Illness. Chest. 144:848-858. 2013
- Approach to the Diagnosis and Management of Drug-Induced Immune Thrombocytopenia. Transfusion Medicine Reviews. 27:137-145. 2013
- FcγRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia. Journal of Thrombosis and Haemostasis. 11:1146-1153. 2013
- Anti–protamine-heparin antibodies: incidence, clinical relevance, and pathogenesis. Blood. 121:2821-2827. 2013
- Anti‐PF4/heparin antibodies and venous graft occlusion in postcoronary artery bypass surgery patients randomized to postoperative unfractionated heparin or fondaparinux thromboprophylaxis. Journal of Thrombosis and Haemostasis. 11:253-260. 2013
- A systematic evaluation of laboratory testing for drug‐induced immune thrombocytopenia. Journal of Thrombosis and Haemostasis. 11:169-176. 2013
- Transient pseudothrombocytopenia associated with immune heparin-induced thrombocytopenia complicated by pulmonary embolism. Thrombosis and Haemostasis. 109:971-973. 2013
- Aspirin for Dual Prevention of Venous and Arterial Thrombosis. New England Journal of Medicine. 367:2039-2041. 2012
- Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis. Blood. 120:4160-4167. 2012
- Heparin-Induced Thrombocytopenia in the ICU. Chest. 142:815-816. 2012
- Acute Hepatic Necrosis and Ischemic Limb Necrosis. New England Journal of Medicine. 367:879-881. 2012
- A prospective study measuring the development of antibodies against platelet factor 4–heparin in healthy males after exposure to heparins. Journal of Thrombosis and Haemostasis. 10:1446-1449. 2012
- Old blood bad? Either the biggest issue in transfusion medicine or a nonevent. Transfusion. 52:1165-1167. 2012
- The effect of blood storage duration on in‐hospital mortality: a randomized controlled pilot feasibility trial. Transfusion. 52:1203-1212. 2012
- Toward better utilization of laboratory resources: The impact of a mandatory 4Ts pretest clinical assessment form on the diagnosis of heparin-induced thrombocytopenia. British Columbia Medical Journal. 54:244-247. 2012
- HITlights: A career perspective on heparin‐induced thrombocytopenia. American Journal of Hematology. 87:S92-S99. 2012
- Hemodialysis-Associated Acute Systemic Reactions and Heparin-Induced Thrombocytopenia. Thrombosis Research. 129:405-406. 2012
- Reversing Anticoagulant Therapy. Current Drug Discovery Technologies. 9:143-149. 2012
- Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding. Blood. 119:2172-2174. 2012
- Storage of thawed plasma for a liquid plasma bank: impact of temperature and methylene blue pathogen inactivation. Transfusion. 52:529-536. 2012
- HIT: treatment easier, prevention harder. Blood. 119:1099-1100. 2012
- Consequences of suspected heparin-induced thrombocytopenia in the ICU. Critical Care. 16:p423. 2012
- Intraoperative anticoagulation and limb amputations in patients with immune heparin‐induced thrombocytopenia who require vascular surgery. Journal of Thrombosis and Haemostasis. 10:148-150. 2012
- Optical Densities Reduce Odds of Heparin-induced Thrombocytopenia Over-diagnosis. American Journal of Medicine. 125:3-4. 2012
- Prognostic importance of preoperative anti-PF4/heparin antibodies in patients undergoing cardiac surgery. Thrombosis and Haemostasis. 107:8-14. 2012
- The serological profile of early-onset and persisting post-cardiac surgery thrombocytopenia complicated by “true” heparin-induced thrombocytopenia. Thrombosis and Haemostasis. 107:998-1000. 2012
- The serological profile of fondaparinux-associated heparin-induced thrombocytopenia syndrome. Thrombosis and Haemostasis. 108:394-396. 2012
- How I Diagnose and Manage HIT. Hematology. American Society of Hematology. Education Program. 2011:143-149. 2011
- Fondaparinux treatment of acute heparin‐induced thrombocytopenia confirmed by the serotonin‐release assay: a 30‐month, 16‐patient case series. Journal of Thrombosis and Haemostasis. 9:2389-2396. 2011
- Laboratory testing for heparin‐induced thrombocytopenia: a conceptual framework and implications for diagnosis. Journal of Thrombosis and Haemostasis. 9:2498-2500. 2011
- 4Ts HIT Scoring in the Medical-Surgical ICU. Blood. 118:4669-4669. 2011
- Identifying Drugs Implicated in Drug-Induced Immune Thrombocytopenia Using Levels of Evidence Applied to Laboratory Tests,. Blood. 118:3304-3304. 2011
- Laboratory HIT Testing in Critically Ill Patients. Blood. 118:198-198. 2011
- A Novel Sickling Hemoglobinopathy. New England Journal of Medicine. 365:1548-1549. 2011
- Heparin-Induced Thrombocytopenia in Critically Ill Patients. Critical Care Clinics. 27:805-823. 2011
- Randomized trial of fondaparinux versus heparin to prevent graft failure after coronary artery bypass grafting: the Fonda CABG study. Journal of Thrombosis and Thrombolysis. 32:378-385. 2011
- Dalteparin and Heparin-Induced Thrombocytopenia. New England Journal of Medicine. 365:1158-1158. 2011
- Combined use of the high heparin step and optical density to optimize diagnostic sensitivity and specificity of an anti-PF4/heparin enzyme-immunoassay. Thrombosis Research. 128:256-260. 2011
- Heparin-Induced Thrombocytopenia: Real-World Issues. Seminars in Thrombosis and Hemostasis. 37:653-663. 2011
- Prevalence and Risk of Preexisting Heparin-Induced Thrombocytopenia Antibodies in Patients With Acute VTE. Chest. 140:366-373. 2011
- Prospective multicentre cohort study of heparin‐induced thrombocytopenia in acute ischaemic stroke patients. British Journal of Haematology. 154:378-386. 2011
- Chills and limb pain following administration of low‐molecular‐weight heparin for treatment of acute venous thromboembolism. American Journal of Hematology. 86:603-606. 2011
- HIT paradigms and paradoxes. Journal of Thrombosis and Haemostasis. 9:105-117. 2011
- Treatment and Prevention of Heparin-Induced Thrombocytopenia: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition) (vol 133, pg 340S, 2008). Chest. 139:1261-1261. 2011
- Dalteparin versus Unfractionated Heparin in Critically Ill Patients. New England Journal of Medicine. 364:1305-1314. 2011
- PROphylaxis for ThromboEmbolism in Critical Care Trial protocol and analysis plan. Journal of Critical Care. 26:223.e1-223.e9. 2011
- The association between platelet activation and FcγRIIa proteolysis. Journal of Thrombosis and Haemostasis. 9:885-887. 2011
- Impact of laboratory testing for heparin-induced antibodies: using Bayes' rule to prevent overdiagnosis of heparin-induced thrombocytopenia/Bedeutung von Laboruntersuchungen von Heparin-induzierten Antikörpern: Einsatz des Bayes Wahrscheinlichkeitstheorems zur Prävention der Überdiagnose einer Heparin-induzierten Thrombozytopenie. Journal of Laboratory Medicine. 35:45-54. 2011
- Venous limb gangrene and fatal hemorrhage: Adverse consequences of hit “overdiagnosis” in a patient with antiphospholipid syndrome. American Journal of Hematology. 86:188-191. 2011
- Fondaparinux: does it cause HIT? can it treat HIT?. Expert Review of Hematology. 3:567-581. 2010
- The 4T and Chong Scores Correlate With Outcomes for Heparin-Induced Thrombocytopenia. Chest. 138:188A-188A. 2010
- DITP causation: 3 methods better than 1?. Blood. 116:2002-2003. 2010
- Heparin‐induced thrombocytopenia: towards standardization of platelet factor 4/heparin antigen tests. Journal of Thrombosis and Haemostasis. 8:2025-2031. 2010
- Agents for the Treatment of Heparin-Induced Thrombocytopenia. Hematology/Oncology Clinics of North America. 24:755-775. 2010
- Incidence and clinical relevance of anti–platelet factor 4/heparin antibodies before cardiac surgery. American Heart Journal. 160:362-369. 2010
- Transfusion premedication to prevent acute transfusion reactions: a retrospective observational study to assess current practices. Transfusion. 50:1722-1730. 2010
- Non‐necrotizing heparin‐induced skin lesions and the 4T’s score. Journal of Thrombosis and Haemostasis. 8:1483-1485. 2010
- Posttransfusion platelet count increments after ABO‐compatible versus ABO‐incompatible platelet transfusions in noncancer patients: an observational study. Transfusion. 50:1552-1560. 2010
- Regression Analysis with a Misclassified Covariate from a Current Status Observation Scheme. Biometrics. 66:415-425. 2010
- The 4Ts scoring system for heparin-induced thrombocytopenia in medical-surgical intensive care unit patients. Journal of Critical Care. 25:287-293. 2010
- Transient Global Amnesia as the Presenting Feature of Heparin-Induced Thrombocytopenia. Journal of Cardiac Surgery. 25:300-302. 2010
- HIT: more than just heparin. Blood. 115:1664-1665. 2010
- Anti‐PF4/heparin antibody formation postorthopedic surgery thromboprophylaxis: the role of non‐drug risk factors and evidence for a stoichiometry‐based model of immunization. Journal of Thrombosis and Haemostasis. 8:504-512. 2010
- Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura. Blood. 115:29-31. 2010
- Early‐onset and persisting thrombocytopenia in post‐cardiac surgery patients is rarely due to heparin‐induced thrombocytopenia, even when antibody tests are positive. Journal of Thrombosis and Haemostasis. 8:30-36. 2010
- Fondaparinux thromboprophylaxis-associated heparin-induced thrombocytopenia syndrome complicated by arterial thrombotic stroke. Thrombosis and Haemostasis. 104:1071-1072. 2010
- Heyde’s syndrome: From controversy to mainstream. Thrombosis and Haemostasis. 103:251-253. 2010
- Studies of the anti–platelet factor 4/heparin immune response: adapting the enzyme‐linked immunosorbent spot assay for detection of memory B cells against complex antigens. Transfusion. 50:32-39. 2010
- The use of well‐characterized sera for the assessment of new diagnostic enzyme‐immunoassays for the diagnosis of heparin‐induced thrombocytopenia. Journal of Thrombosis and Haemostasis. 8:216-218. 2010
- Inter-Rater Reliability of the 4Ts Scoring System for Diagnosing Heparin-Induced Thrombocytopenia in Critically Ill Patients.. Blood. 114:3995-3995. 2009
- Immune mechanisms in heparin‐induced thrombocytopenia: no evidence for immunoglobulin M anti‐idiotype antibodies. Transfusion. 49:1812-1818. 2009
- The paradox of heparin‐induced thrombocytopenia. Journal of Thrombosis and Haemostasis. 7:1472-1473. 2009
- Immunoassays are not created equal. Journal of Thrombosis and Haemostasis. 7:1256-1259. 2009
- Antiphospholipid and anti‐PF4 antibodies: an association affecting anti‐PF4/heparin assay analysis. Journal of Thrombosis and Haemostasis. 7:1067-1069. 2009
- Preface. Journal of Thrombosis and Haemostasis. 7:1-1. 2009
- Suboptimal effect of a three‐factor prothrombin complex concentrate (Profilnine‐SD) in correcting supratherapeutic international normalized ratio due to warfarin overdose. Transfusion. 49:1171-1177. 2009
- Studies of the immune response in heparin-induced thrombocytopenia. Blood. 113:4963-4969. 2009
- The temporal profile of the anti-PF4/heparin immune response. Blood. 113:4970-4976. 2009
- Adverse Prognostic Significance of Thrombocytopenia in Acute Coronary Syndrome. Circulation. 119:2420-2422. 2009
- Heparin-Induced Thrombocytopenia in Patients with Ventricular Assist Devices: Are New Prevention Strategies Required?. Annals of Thoracic Surgery. 87:1633-1640. 2009
- Heparin-induced anaphylactic and anaphylactoid reactions: two distinct but overlapping syndromes. Expert Opinion on Drug Safety. 8:129-144. 2009
- Heparin‐induced thrombocytopenia (HIT) during postoperative warfarin thromboprophylaxis: a second example of postorthopedic surgery ‘spontaneous’ HIT. Journal of Thrombosis and Haemostasis. 7:499-501. 2009
- Current perspective of venous thrombosis in the upper extremity: a rebuttal. Journal of Thrombosis and Haemostasis. 7:237-238. 2009
- Formation of anti–platelet factor 4/heparin antibodies after cardiac surgery: Influence of perioperative platelet activation, the inflammatory response, and histocompatibility leukocyte antigen status. Journal of Thoracic and Cardiovascular Surgery. 136:1456-1463. 2008
- Heparin‐induced thrombocytopenia – therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4–heparin complexes. Journal of Thrombosis and Haemostasis. 6:2160-2167. 2008
- Delayed‐onset HIT caused by low‐molecular‐weight heparin manifesting during fondaparinux prophylaxis. American Journal of Hematology. 83:876-878. 2008
- Heparin-induced thrombocytopenia: a historical perspective. Blood. 112:2607-2616. 2008
- Risk of heparin-induced thrombocytopenia in patients receiving thromboprophylaxis. Expert Review of Hematology. 1:75-85. 2008
- Contaminated Heparin. New England Journal of Medicine. 359:1291-1293. 2008
- An algorithm for resolving ‘indeterminate’ test results in the platelet serotonin release assay for investigation of heparin‐induced thrombocytopenia. Journal of Thrombosis and Haemostasis. 6:1595-1597. 2008
- Fatal heparin‐induced thrombocytopenia (HIT) during warfarin thromboprophylaxis following orthopedic surgery: another example of ‘spontaneous’ HIT?. Journal of Thrombosis and Haemostasis. 6:1598-1600. 2008
- “Spare-spleen-uximab” for chronic ITP. Blood. 112:925-926. 2008
- Quantitative interpretation of optical density measurements using PF4‐dependent enzyme‐immunoassays. Journal of Thrombosis and Haemostasis. 6:1304-1312. 2008
- A Spontaneous Prothrombotic Disorder Resembling Heparin-induced Thrombocytopenia. American Journal of Medicine. 121:632-636. 2008
- Can heparin‐induced thrombocytopenia be associated with fondaparinux use? Reply to a rebuttal. Journal of Thrombosis and Haemostasis. 6:1243-1246. 2008
- Analysis of a nonsusceptible fraction with current status data. Statistics in Medicine. 27:2715-2730. 2008
- Treatment and Prevention of Heparin-Induced Thrombocytopenia. Chest. 133:340S-380S. 2008
- Bleeding risk and the management of bleeding complications in patients undergoing anticoagulant therapy: focus on new anticoagulant agents. Blood. 111:4871-4879. 2008
- Heparin-induced thrombocytopenia in patients requiring prolonged intensive care unit treatment after cardiopulmonary bypass. Journal of Thrombosis and Haemostasis. 6:428-435. 2008
- The Approach to Heparin-Induced Thrombocytopenia. Seminars in Respiratory and Critical Care Medicine. 29:066-074. 2008
- Bivalirudin. Thrombosis and Haemostasis. 99:830-839. 2008
- Confirmatory procedure and other maneuvers to assess pathogenicity of platelet factor 4 (PF4)-dependent antibodies – distinguishing "signal" from "noise". Thrombosis and Haemostasis. 100:523-524. 2008
- Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT) – Bridging the River Coumarin. Thrombosis and Haemostasis. 99:2-3. 2008
- Heparin-induced thrombocytopenia: A stoichiometry-based model to explain the differing immunogenicities of unfractionated heparin, low-molecular-weight heparin, and fondaparinux in different clinical settings. Thrombosis Research. 122:211-220. 2008
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- The direct thrombin inhibitor hirudin. Thrombosis and Haemostasis. 99:819-829. 2008
- What is the potential for overdiagnosis of heparin‐induced thrombocytopenia?. American Journal of Hematology. 82:1037-1043. 2007
- Performance characteristics of a rapid assay for anti‐PF4/heparin antibodies: the particle immunofiltration assay. Journal of Thrombosis and Haemostasis. 5:2308-2310. 2007
- So, Does Low-Molecular-Weight Heparin Cause Less Heparin-Induced Thrombocytopenia Than Unfractionated Heparin or Not?. Chest. 132:1108-1110. 2007
- Acute pancreatitis preceding thrombotic thrombocytopenic Purpura. Haematologica. 92:e94-e95. 2007
- Perioperative management of MYH9 hereditary macrothrombocytopenia (Fechtner syndrome). European Journal of Haematology. 79:263-268. 2007
- Heparin-Induced Thrombocytopenia. Hematology/Oncology Clinics of North America. 21:589-607. 2007
- Heparin‐induced thrombocytopenia: a prospective study on the incidence, platelet‐activating capacity and clinical significance of antiplatelet factor 4/heparin antibodies of the IgG, IgM, and IgA classes. Journal of Thrombosis and Haemostasis. 5:1666-1673. 2007
- Very severe thrombocytopenia and fragmentation hemolysis mimicking thrombotic thrombocytopenic purpura associated with a giant intracardiac vegetation infected with Staphylococcus epidermidis: Role of monocyte procoagulant activity induced by bacterial supernatant. American Journal of Hematology. 82:766-771. 2007
- Warfarin Cessation Before Cardiopulmonary Bypass: Lessons Learned from a Randomized Controlled Trial of Oral Vitamin K. Annals of Thoracic Surgery. 84:103-108. 2007
- Heparin-Induced Thrombocytopenia Associated with Fondaparinux. New England Journal of Medicine. 356:2653-2655. 2007
- Case report: Management of immediate post-car-diopulmonary bypass massive intra-cardiac thrombosis. Canadian Journal of Anaesthesia. 54:461-466. 2007
- Who Is (Still) Getting HIT?. Chest. 131:1620-1622. 2007
- Minimizing costs for treating deep vein thrombosis: the role for fondaparinux. Journal of Thrombosis and Thrombolysis. 23:229-236. 2007
- Heparin-induced thrombocytopenia in intensive care patients. Critical Care Medicine. 35:1165-1176. 2007
- Clinical sample investigation (CSI) hematology: pinpointing the precise onset of heparin‐induced thrombocytopenia (HIT). Journal of Thrombosis and Haemostasis. 5:636-637. 2007
- Drug-Induced Immune-Mediated Thrombocytopenia — From Purpura to Thrombosis. New England Journal of Medicine. 356:891-893. 2007
- PF4‐dependent immunoassays and inferential detection of HIT antibodies. Journal of Thrombosis and Haemostasis. 5:232-234. 2007
- Delayed-onset heparin-induced thrombocytopenia, venous thromboembolism, and cerebral venous thrombosis: A consequence of heparin “flushes”. Thrombosis and Haemostasis. 98:1139-1140. 2007
- Laboratory testing for heparin-induced thrombocytopenia is inconsistent in North America: A survey of North American specialized coagulation laboratories. Thrombosis and Haemostasis. 98:1357-1361. 2007
- When is HIT Really HIT?. Annals of Thoracic Surgery. 83:21-23. 2007
- Heparin-induced thrombocytopenia in the critical care setting: Diagnosis and management^. Critical Care Medicine. 34:2898-2911. 2006
- An Algorithm for “Indeterminate” Test Results in the Platelet Serotonin Release Assay for Heparin-Induced Thrombocytopenia (HIT).. Blood. 108:1048-1048. 2006
- Efficacy of Prothrombin Complex Concentrate (PCC) for Reversal of Warfarin Effect.. Blood. 108:964-964. 2006
- Platelet-Activating Anti-Platelet Factor 4/Polyanion Antibodies without Preceding Heparin Therapy: A Transient Autoimmune Disorder Resembling Heparin-Induced Thrombocytopenia (“Spontaneous HIT”).. Blood. 108:1047-1047. 2006
- Gender imbalance and risk factor interactions in heparin-induced thrombocytopenia. Blood. 108:2937-2941. 2006
- Close Approximation of Two Platelet Factor 4 Tetramers by Charge Neutralization Forms the Antigens Recognized by HIT Antibodies. Arteriosclerosis, Thrombosis and Vascular Biology. 26:2386-2393. 2006
- MINIMIZING COSTS FOR TREATING DEEP VEIN THROMBOSIS: THE ROLE FOR FONDAPARINUX. Chest. 130:260S-260S. 2006
- Testing for Heparin-Induced Thrombocytopenia Antibodies. Transfusion Medicine Reviews. 20:259-272. 2006
- Lepirudin: walking the dosing line. Blood. 108:1428-1429. 2006
- Think of HIT When Thrombosis Follows Heparin. Chest. 130:631-632. 2006
- Thrombotic End Point for Assessing Argatroban Therapy for Heparin-Induced Thrombocytopenia. Chest. 129:1396-1398. 2006
- Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin‐induced thrombocytopenia in two clinical settings. Journal of Thrombosis and Haemostasis. 4:759-765. 2006
- Should vitamin K be administered when HIT is diagnosed after administration of coumarin?. Journal of Thrombosis and Haemostasis. 4:894-896. 2006
- HIT without (more) heparin. Blood. 107:2214-2215. 2006
- Anticoagulation for cardiopulmonary bypass: Is a replacement for heparin on the horizon?. Journal of Thoracic and Cardiovascular Surgery. 131:515-516. 2006
- Systematic underestimation of anemia severity in postoperative patients. Transfusion. 46:317-318. 2006
- Thrombocytopenia associated with the use of GPIIb/IIIa inhibitors: position paper of the ISTH working group on thrombocytopenia and GPIIb/IIIa inhibitors. Journal of Thrombosis and Haemostasis. 4:678-679. 2006
- No significant improvement in diagnostic specificity of an anti‐PF4/polyanion immunoassay with use of high heparin confirmatory procedure. Journal of Thrombosis and Haemostasis. 4:281-282. 2006
- Recognition, treatment, and prevention of heparin-induced thrombocytopenia: Review and update. Thrombosis Research. 118:165-176. 2006
- Results of a systematic evaluation of treatment outcomes for heparin-induced thrombocytopenia in patients receiving danaparoid, ancrod, and/or coumarin explain the rapid shift in clinical practice during the 1990s. Thrombosis Research. 117:507-515. 2006
- Think of HIT. Hematology. American Society of Hematology. Education Program. 2006:408-414. 2006
- Anti–platelet factor 4/heparin antibodies in orthopedic surgery patients receiving antithrombotic prophylaxis with fondaparinux or enoxaparin. Blood. 106:3791-3796. 2005
- Laboratory testing for the antibodies that cause heparin-induced thrombocytopenia: How much class do we need?. Translational Research. 146:341-346. 2005
- Thrombocytopenia in medical-surgical critically ill patients: prevalence, incidence, and risk factors. Journal of Critical Care. 20:348-353. 2005
- Towards a Conceptual Framework for Diagnosis of Heparin-Induced Thrombocytopenia (HIT).. Blood. 106:1234-1234. 2005
- Immune Thrombocytopenia Associated with Efalizumab Therapy for Psoriasis. ACP journal club. 143:761-761. 2005
- Unfractionated LMWH and the risk of HIT: are medical patients different?. Blood. 106:2931-2932. 2005
- HIT as a preventable disease?. Blood. 106:2600-2600. 2005
- Replacement of unfractionated heparin by low-molecular-weight heparin for postorthopedic surgery antithrombotic prophylaxis lowers the overall risk of symptomatic thrombosis because of a lower frequency of heparin-induced thrombocytopenia. Blood. 106:2921-2922. 2005
- Transfusion Medicine in the Era of Genomics and Proteomics. Transfusion Medicine Reviews. 19:288-294. 2005
- Should Aspirin Be Discontinued Before Coronary Artery Bypass Surgery?. Circulation. 112:e85-e90. 2005
- Thrombosis of the Cerebral Veins and Sinuses. New England Journal of Medicine. 353:314-315. 2005
- Bivalirudin: a review. Expert Opinion on Pharmacotherapy. 6:1349-1371. 2005
- Heparin, Low Molecular Weight Heparin, and Heparin-Induced Thrombocytopenia in the ICU. Critical Care Clinics. 21:513-529. 2005
- Heparin-Induced Skin Lesions and Other Unusual Sequelae of the Heparin-Induced Thrombocytopenia Syndrome. Chest. 127:1857-1861. 2005
- Immune heparin-induced thrombocytopenia can occur in patients receiving clopidogrel and aspirin. American Journal of Hematology. 78:188-192. 2005
- Heparin-Induced Thrombocytopenia. Disease-a-Month. 51:141-149. 2005
- New Approaches to the Diagnosis of Heparin-Induced Thrombocytopenia. Chest. 127:35S-45S. 2005
- Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis. Thrombosis and Haemostasis. 94:132-135. 2005
- Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation. Thrombosis and Haemostasis. 94:958-964. 2005
- Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin. Blood. 105:139-144. 2005
- Argatroban as a Heparin Substitute in Cases of Heparin-Induced Thrombocytopenia. Annals of Thoracic Surgery. 78:2208-2208. 2004
- Dissociation between the level of von Willebrand factor‐cleaving protease activity and disease in a patient with congenital thrombotic thrombocytopenic purpura. American Journal of Hematology. 77:387-390. 2004
- Reply. Annals of Thoracic Surgery. 78:2208-2209. 2004
- Laboratory Testing for Hit Antibodies: How Much Class Do We Need?.. Blood. 104:3022-3022. 2004
- Heparin-Induced Thrombocytopenia. Circulation. 110:e454-e458. 2004
- Heparin-Induced Thrombocytopenia: Recognition, Treatment, and Prevention. Chest. 126:311S-337S. 2004
- Hypotensive transfusion reactions can occur with blood products that are leukoreduced before storage. Transfusion. 44:1361-1366. 2004
- Cardiobacterium hominis endocarditis associated with very severe thrombocytopenia and platelet autoantibodies. American Journal of Hematology. 76:373-377. 2004
- Bloody easy: blood transfusions, blood alternatives and transfusion reactions. A guide to transfusion medicine. (Web site: www.sunnybrookandwomens.on.ca)Edited by Callum JL, Pinkerton PH. Sunnybrook & Women’s College Health Sciences Centre, Toronto, ON, 2003. Transfusion Medicine Reviews. 18:233-234. 2004
- An Overview of the Heparin-Induced Thrombocytopenia Syndrome. Seminars in Thrombosis and Hemostasis. 30:273-283. 2004
- Randomized Trial of Warfarin Nomograms. ACP journal club. 140:488-488. 2004
- Randomized trial of warfarin nomograms.. ACP journal club. 140:490-491. 2004
- Bivalent direct thrombin inhibitors: hirudin and bivalirudin. Best Practice and Research in Clinical Haematology. 17:105-125. 2004
- Invited commentary. Annals of Thoracic Surgery. 77:931-931. 2004
- Heparin-Induced Thrombocytopenia and Vascular Surgery. Acta Chirurgica Belgica. 104:257-265. 2004
- Thrombocytopenia in medical–surgical ICU patients. Critical Care. 8:P125-P125. 2004
- Warfarin‐associated multiple digital necrosis complicating heparin‐induced thrombocytopenia and Raynaud's phenomenon after aortic valve replacement for adenocarcinoma‐associated thrombotic endocarditis. American Journal of Hematology. 75:56-62. 2004
- Heparin-induced thrombocytopenia and cardiac surgery. Annals of Thoracic Surgery. 76:2121-2131. 2003
- An Improved Definition of Immune Heparin-Induced Thrombocytopenia in Postoperative Orthopedic Patients. JAMA Internal Medicine. 163:2518-2518. 2003
- Selective thrombocytopenia in children with Wilms tumor: An immune‐mediated effect of dactinomycin?. Pediatric Blood and Cancer. 41:483-485. 2003
- Gastrointestinal bleeding, angiodysplasia, cardiovascular disease, and acquired von Willebrand syndrome. Transfusion Medicine Reviews. 17:272-286. 2003
- Gastrointestinal bleeding, angiodysplasia, cardiovascular disease, and acquired von Willebrand syndrome. Transfusion Medicine Reviews. 17:272-286. 2003
- Heparin‐induced thrombocytopenia: pathogenesis and management. British Journal of Haematology. 123:373-374. 2003
- Heparin‐induced thrombocytopenia: pathogenesis and management – Response to Rasheed Saad. British Journal of Haematology. 123:374-375. 2003
- The IgG subclasses of platelet‐associated autoantibodies directed against platelet glycoproteins IIb/IIIa in patients with idiopathic thrombocytopenic purpura. British Journal of Haematology. 122:818-824. 2003
- Heparin-induced thrombocytopenia and cardiac surgery. Annals of Thoracic Surgery. 76:638-648. 2003
- In Reply. Archives of Pathology and Laboratory Medicine. 127:783-783. 2003
- Platelet Count Monitoring and Laboratory Testing for Heparin-Induced Thrombocytopenia. Archives of Pathology and Laboratory Medicine. 127:782-783. 2003
- Platelet count monitoring and laboratory testing for heparin-induced thrombocytopenia - Reply. Archives of Pathology and Laboratory Medicine. 127:783-783. 2003
- Heparin‐induced thrombocytopenia: pathogenesis and management. British Journal of Haematology. 121:535-555. 2003
- Management of heparin-induced thrombocytopenia: a critical comparison of lepirudin and argatroban. Thrombosis Research. 110:73-82. 2003
- Prothrombotic genetic risk factors and heparin-induced thrombocytopenia. Pharmacogenetics and Genomics. 13:245-246. 2003
- Central venous catheters and upper-extremity deep-vein thrombosis complicating immune heparin-induced thrombocytopenia. Blood. 101:3049-3051. 2003
- Heparin-induced thrombocytopenia in medical patients. Blood. 101:2903-2903. 2003
- Delayed-Onset Heparin-Induced Thrombocytopenia and Cerebral Thrombosis after a Single Administration of Unfractionated Heparin. New England Journal of Medicine. 348:1067-1069. 2003
- Laboratory diagnosis of immune heparin-induced thrombocytopenia.. Current hematology reports. 2:148-157. 2003
- Agreements Between the Prothrombin Times of Blood Treated In Vitro with Heparinase During Cardiopulmonary Bypass (CPB) and Blood Sampled After CPB and Systemic Protamine. Anesthesia and Analgesia. 96:15-20. 2003
- Invited commentary. Annals of Thoracic Surgery. 75:284-285. 2003
- Platelet-Endothelial Interactions: Sepsis, HIT, and Antiphospholipid Syndrome. Hematology. American Society of Hematology. Education Program. 2003:497-519. 2003
- Pork or beef?. Annals of Thoracic Surgery. 75:15-16. 2003
- Platelet Count Monitoring and Laboratory Testing for Heparin-Induced Thrombocytopenia. Archives of Pathology and Laboratory Medicine. 126:1415-1423. 2002
- Gastrointestinal Angiodysplasia and Aortic Stenosis. New England Journal of Medicine. 347:858-859. 2002
- Comment: Treatment of Heparin-Induced Thrombocytopenia. Annals of Pharmacotherapy. 36:1483-1484. 2002
- Current agents for the treatment of patients with heparin-induced thrombocytopenia. Current Opinion in Pulmonary Medicine. 8:405-412. 2002
- Current agents for the treatment of patients with heparin-induced thrombocytopenia. Current Opinion in Pulmonary Medicine. 8:405-412. 2002
- Heparin-Induced Thrombocytopenia. Current hematology reports. 1:63-72. 2002
- Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin‐induced thrombocytopenia. American Journal of Hematology. 71:50-52. 2002
- Abstract. Canadian Journal of Anaesthesia. 49:A60-A148. 2002
- Heparin-induced thrombocytopenia and the anesthesiologist.. Canadian Journal of Anaesthesia. 49:S36-S49. 2002
- Heparin-induced thrombocytopenia, Part 1: The diagnostic clues: An abrupt decline in platelet count is telling. Journal of Critical Illness. 17:172-178. 2002
- Heparin-induced thrombocytopenia, part 2: Clinical course and treatment. How can drug selection help spare life and limb?. Journal of Critical Illness. 17:215-221. 2002
- Reversing anticoagulants both old and new.. Canadian Journal of Anaesthesia. 49:S11-S25. 2002
- Off-pump coronary artery bypass grafting for acute heparin-induced thrombocytopenia. Annals of Thoracic Surgery. 72:1730-1732. 2001
- Venous Limb Gangrene during Warfarin Treatment of Cancer-Associated Deep Venous Thrombosis. ACP journal club. 135:589-589. 2001
- Delayed-Onset Heparin-Induced Thrombocytopenia and Thrombosis. ACP journal club. 135:502-502. 2001
- Decreased von Willebrand factor protease activity associated with thrombocytopenic disorders. Blood. 98:1842-1846. 2001
- Heparin-Induced Thrombocytopenia. New England Journal of Medicine. 345:619-620. 2001
- Temporal Aspects of Heparin-Induced Thrombocytopenia. New England Journal of Medicine. 344:1286-1292. 2001
- Argatroban. Drugs. 61:523-524. 2001
- Heparin and Low-Molecular-Weight Heparin Mechanisms of Action, Pharmacokinetics, Dosing, Monitoring, Efficacy, and Safety. Chest. 119:64S-94S. 2001
- Heparin-induced Thrombocytopenia: Yet Another Treatment Paradox?. Thrombosis and Haemostasis. 85:947-949. 2001
- Delayed onset of life-threatening immune hemolysis after perioperative antimicrobial prophylaxis with cefotetan.. Canadian Journal of Surgery. 43:461-462. 2000
- Evaluation of platelet morphology and the subcellular distribution of PAIgG in patients with ITP and non-immune thrombocytopenia. Blood. 96. 2000
- Expression of cd109 with alternate forms of membrane anchoring unique to platelets and megakaryocytic cell lines. Blood. 96. 2000
- Possible pathways of IGG trafficking in platelets. Blood. 96. 2000
- The impact of idiopathic thrombocytopenic purpura in pregnancy. Blood. 96. 2000
- Treatment of chronic refractory idiopathic thrombocytopenic purpura with cyclophosphamide and cyclosporine. Blood. 96. 2000
- Impact of the patient population on the risk for heparin-induced thrombocytopenia. Blood. 96:1703-1708. 2000
- Morphological analysis of microparticle generation in heparin-induced thrombocytopenia. Blood. 96:188-194. 2000
- Morphological analysis of microparticle generation in heparin-induced thrombocytopenia. Blood. 96:188-194. 2000
- Venous thromboembolism in heparin-induced thrombocytopenia. Current Opinion in Pulmonary Medicine. 6:343-351. 2000
- Laboratory testing for heparin-induced thrombocytopenia.. Journal of Thrombosis and Thrombolysis. 10:35-45. 2000
- Heparin-induced thrombocytopenia. Canadian Journal of Hospital Pharmacy. 52:362-369. 1999
- Measurement of endogenous and exogenous alpha‐granular platelet proteins in patients with immune and nonimmune thrombocytopenia. British Journal of Haematology. 106:762-770. 1999
- Multicentric warfarin-induced skin necrosis complicating heparin-induced thrombocytopenia. American Journal of Hematology. 62:44-48. 1999
- A prospective study of protein‐specific assays used to investigate idiopathic thrombocytopenic purpura. British Journal of Haematology. 104:442-447. 1999
- Heparin-Induced Thrombocytopenia: A Ten-Year Retrospective. Annual Review of Medicine. 50:129-147. 1999
- Newer Strategies for the Treatment of Heparin‐Induced Thrombocytopenia. Pharmacotherapy. 19:181-195. 1999
- Serum-induced platelet procoagulant activity: An assay for the characterization of prothrombotic disorders. Translational Research. 133:129-133. 1999
- Generation of platelet-derived microparticles and procoagulant activity by heparin-induced thrombocytopenia IgG/serum and other IgG platelet agonists: a comparison with standard platelet agonists. Platelets. 10:319-326. 1999
- Heparin-Induced Thrombocytopenia: A Clinicopathologic Syndrome. Thrombosis and Haemostasis. 82:439-447. 1999
- Intraoperative Heparin Flushes and Subsequent Acute Heparin-induced Thrombocytopenia . Anesthesiology. 89:1567-1569. 1998
- Heparin and Low-Molecular-Weight Heparin. Chest. 114:489S-510S. 1998
- Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety.. Chest. 114:489S-510S. 1998
- Clinical presentation of heparin-induced thrombocytopenia.. Seminars in Hematology. 35:9-16. 1998
- Limitations of conventional treatment options for heparin-induced thrombocytopenia.. Seminars in Hematology. 35:17-25. 1998
- ABH antigens on human platelets: Expression on the glycosyl phosphatidylinositol-anchored protein CD109. Translational Research. 132:142-148. 1998
- Heparin-induced thrombocytopenia. Postgraduate Medicine. 103:169-178. 1998
- Factor V Leiden and Thrombotic Complications in Heparin-induced Thrombocytopenia. Thrombosis and Haemostasis. 79:50-53. 1998
- Heparin-induced Thrombocytopenia: Towards Consensus. Thrombosis and Haemostasis. 79:1-7. 1998
- Heparin-induced thrombocytopenia. Surgeon. 27:109-113. 1998
- Heparin-Induced Thrombocytopenia. Drug Safety. 17:325-341. 1997
- The Pathogenesis of Venous Limb Gangrene Associated with Heparin-Induced Thrombocytopenia. ACP journal club. 127:804-804. 1997
- The alloimmune thrombocytopenic syndromes. Transfusion Medicine Reviews. 11:296-307. 1997
- Activation of platelets by sera containing igg1 heparin-dependent antibodies: an explanation for the predominance of the Fcγrlla “low responder” (his131) gene in patients with heparin-induced thrombocytopenia. Translational Research. 130:278-284. 1997
- Maternal immunization to Gov system alloantigens on human platelets. Transfusion. 37:823-828. 1997
- Guidelines for red blood cell and plasma transfusion for adults and children. CANADIAN MEDICAL ASSOCIATION JOURNAL. 156:S1-S24. 1997
- PROTEOLYTIC DEGRADATION OF HIGH MOLECULAR WEIGHT KININOGEN IN ACUTE THROMBOTIC THROMBOCYTOPENIC PURPURA. British Journal of Haematology. 97:762-767. 1997
- Failure of pulse high‐dose dexamethasone in chronic idiopathic immune thrombocytopenia. American Journal of Hematology. 54:267-270. 1997
- Guidelines for red blood cell and plasma transfusion for adults and children. CANADIAN MEDICAL ASSOCIATION JOURNAL. 156. 1997
- A diagnostic test for heparin‐induced thrombocytopenia: detection of platelet microparticles using flow cytometry. British Journal of Haematology. 95:724-731. 1996
- A 14-year study of heparin-induced thrombocytopenia. American Journal of Medicine. 101:502-507. 1996
- Heparin-Induced thrombocytopenia: IgG-Mediated platelet activation, platelet microparticle generation, and altered procoagulant/anticoagulant balance in the pathogenesis of thrombosis and venous limb gangrene complicating heparin-Induced thrombocytopenia. Transfusion Medicine Reviews. 10:249-258. 1996
- Heparin-induced thrombocytopenia: What the serologists have taught us. Translational Research. 128:346-348. 1996
- The epitope specificity of heparin‐induced thrombocytopenia. British Journal of Haematology. 95:161-167. 1996
- Splenectomy Done during Hematologic Remission To Prevent Relapse in Patients with Thrombotic Thrombocytopenic Purpura. ACP journal club. 125:294-294. 1996
- Isolation and characterization of cysteine proteinase in thrombotic thrombocytopenic purpura. British Journal of Haematology. 93:421-426. 1996
- Acute hemolytic anemia precipitated by myocardial infarction and pericardial tamponade in G6PD deficiency. American Journal of Hematology. 51:174-175. 1996
- Heparin‐induced skin lesions. British Journal of Haematology. 92:494-497. 1996
- Diagnosis of Heparin-induced Thrombocytopenia:Still a Journey, Not Yet a Destination. American Journal of Clinical Pathology. 104:611-613. 1995
- The prenatal identification of fetal compatibility in neonatal alloimmune thrombocytopenia using amniotic fluid and variable number of tandem repeat (VNTR) analysis. British Journal of Haematology. 91:742-746. 1995
- Heparin-Induced Thrombocytopenia. New England Journal of Medicine. 333:1006-1007. 1995
- Characterization and localization of the Gova/b alloantigens to the glycosylphosphatidylinositol-anchored protein CDw109 on human platelets. Blood. 86:2807-2814. 1995
- Characterization and localization of the Gova/b alloantigens to the glycosylphosphatidylinositol-anchored protein CDw109 on human platelets. Blood. 86:2807-2814. 1995
- Heparin: Mechanism of Action, Pharmacokinetics, Dosing Considerations, Monitoring, Efficacy, and Safety. Chest. 108:258S-275S. 1995
- Heparin: mechanism of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety.. Chest. 108:258S-275S. 1995
- Bacterial infection‐associated improvement of platelet counts in two patients with chronic and unresponsive idiopathic thrombocytopenic purpura with normal platelet survival studies. British Journal of Haematology. 90:332-335. 1995
- Heparin-Induced Thrombocytopenia in Patients Treated with Low-Molecular-Weight Heparin or Unfractionated Heparin. New England Journal of Medicine. 332:1330-1336. 1995
- Hemostasis and atherosclerosis.. Canadian Journal of Cardiology. 11 Suppl C:29C-34C. 1995
- Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia. Blood. 84:3691-3699. 1994
- Transient global amnesia associated with acute heparin-induced thrombocytopenia. American Journal of Medicine. 97:489-491. 1994
- Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4. Blood. 83:3232-3239. 1994
- Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4. Blood. 83:3232-3239. 1994
- Thrombocytopenia and Illicit Drug Use. ACP journal club. 120:693-693. 1994
- Platelet concentrates stored for 5 days in a reduced volume of plasma maintain hemostatic function and viability. Transfusion. 34:44-47. 1994
- Heparin-induced skin necrosis. American Journal of Medicine. 95:662-663. 1993
- Heparin‐induced thrombocytopenia and thrombosis: clinical and laboratory studies. British Journal of Haematology. 84:322-328. 1993
- Multimerin is found in the alpha-granules of resting platelets and is synthesized by a megakaryocytic cell line.. Journal of Clinical Investigation. 91:2630-2639. 1993
- Investigation of human platelet alloantigens and glycoproteins using non-radioactive immunoprecipitation. Journal of Immunological Methods. 158:77-85. 1993
- Letter to the editor. Thrombotic and Haemorrhagic Disorders. 7:61-62. 1993
- Calpain activity in patients with thrombotic thrombocytopenic purpura is associated with platelet microparticles. Blood. 80:2246-2251. 1992
- Thrombotic thrombocytopenic purpura. Blood Coagulation and Fibrinolysis. 3:655-660. 1992
- Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia.. Translational Research. 120:371-379. 1992
- Aortic stenosis and bleeding gastrointestinal angiodysplasia: is acquired von Willebrand's disease the link?. The Lancet. 340:35-37. 1992
- Thrombocytopenia caused by passive transfusion of anti-glycoprotein Ia/IIa alloantibody (anti-HPA-5b). Blood. 79:2480-2484. 1992
- Thrombocytopenia caused by passive transfusion of anti-glycoprotein Ia/IIa alloantibody (anti-HPA-5b). Blood. 79:2480-2484. 1992
- 1ST SUCCESSFUL UNRELATED BONE-MARROW TRANSPLANT IN CANADA. Canadian Family Physician. 38:163-165. 1992
- First successful unrelated bone marrow transplant in Canada: A look at the longest surviving recipient.. Canadian Family Physician. 38:163-165. 1992
- Rapid anticoagulation using ancrod for heparin-induced thrombocytopenia [see comments]. Blood. 78:2194-2197. 1991
- Rapid anticoagulation using ancrod for heparin-induced thrombocytopenia [see comments]. Blood. 78:2194-2197. 1991
- Investigation of the mechanisms of monoclonal antibody-induced platelet activation. Blood. 78:1019-1026. 1991
- Comment: Attribution of Blame in Drug-Induced Thrombocytopenia. Annals of Pharmacotherapy. 25:874-875. 1991
- Multimerin: a series of large disulfide-linked multimeric proteins within platelets. Blood. 77:2556-2560. 1991
- p-155, a multimeric platelet protein that is expressed on activated platelets.. Journal of Biological Chemistry. 266:7114-7120. 1991
- Heparin-induced thrombocytopenia.. Progress in hemostasis and thrombosis. 10:1-34. 1991
- Measurement of fibrinogen binding to platelets in whole blood by flow cytometry: a micromethod for the detection of platelet activation. British Journal of Haematology. 76:387-394. 1990
- Current Concepts in the Treatment of Immune Thrombocytopenia. Drugs. 40:531-542. 1990
- Gova/b alloantigen system on human platelets. Blood. 75:2172-2176. 1990
- Gova/b alloantigen system on human platelets. Blood. 75:2172-2176. 1990
- Heparin and Platelets. Hematology/Oncology Clinics of North America. 4:243-264. 1990
- Recurrent acute splenic sequestration crisis due to interacting genetic defects: hemoglobin SC disease and hereditary spherocytosis. Blood. 75:266-270. 1990
- Heparin-Induced Thrombocytopenia. Annual Review of Medicine. 40:31-44. 1989
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