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Incidence of HPA-9b in Testing for Neonatal...
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Incidence of HPA-9b in Testing for Neonatal Alloimmune Thrombocytopenia.

Abstract

Abstract Background: Neonatal alloimmune thrombocytopenia (NAT) is caused by maternal alloantibodies that cross the placenta and cause increased clearance of fetal platelets. The alloantibodies are directed to incompatible human platelet antigens (HPA) inherited from the father and expressed on fetal platelet glycoproteins. Most cases of NAT are caused by HPA-1a, -5a, -5b, -15a, or -15b. Some are associated with immunization …

Authors

Smith JW; Chamberlain K; Moffatt D; Santos A; Neutel D; Moore J; Warkentin TE; Arnold DM; Kelton JG

Volume

110

Publisher

American Society of Hematology

Publication Date

November 16, 2007

DOI

10.1182/blood.v110.11.3214.3214

Conference proceedings

Blood

Issue

11

ISSN

0006-4971