Diagnosis and Management of Heparin‐Induced Thrombocytopenia

This chapter contains sections titled: Introduction What are the clinical features that suggest a diagnosis of HIT? What laboratory tests are clinically useful for detecting HIT antibodies? What alternative anticoagulants are efficacious for treatment of thrombosis complicating HIT? Why is warfarin (coumarin) anticoagulation contraindicated during acute HIT? What is the natural history of isolated HIT? Can HIT be prevented? Should routine platelet count monitoring for HIT be performed in some circumstances? Is deliberate reexposure to heparin ever warranted in a patient with previous HIT? References Introduction What are the clinical features that suggest a diagnosis of HIT? What laboratory tests are clinically useful for detecting HIT antibodies? What alternative anticoagulants are efficacious for treatment of thrombosis complicating HIT? Why is warfarin (coumarin) anticoagulation contraindicated during acute HIT? What is the natural history of isolated HIT? Can HIT be prevented? Should routine platelet count monitoring for HIT be performed in some circumstances? Is deliberate reexposure to heparin ever warranted in a patient with previous HIT? References