Journal article
The IgG subclasses of platelet‐associated autoantibodies directed against platelet glycoproteins IIb/IIIa in patients with idiopathic thrombocytopenic purpura
Abstract
The majority of patients with idiopathic thrombocytopenic purpura (ITP) have antiplatelet autoantibodies that are most frequently directed against platelet glycoproteins IIb/IIIa or Ib/IX/V. However, there is some debate whether the immune response is oligoclonal or polyclonal in nature. We investigated the subclass distribution of anti-IIb/IIIa IgG autoantibodies in 59 prospectively studied patients with ITP. We also tested patients with a …
Authors
Chan H; Moore JC; Finch CN; Warkentin TE; Kelton JG
Journal
British Journal of Haematology, Vol. 122, No. 5, pp. 818–824
Publisher
Wiley
Publication Date
9 2003
DOI
10.1046/j.1365-2141.2003.04509.x
ISSN
0007-1048