Journal article
Failure of pulse high‐dose dexamethasone in chronic idiopathic immune thrombocytopenia
Abstract
Idiopathic thrombocytopenic purpura (ITP) is a disorder characterized by increased platelet destruction in the setting of normal megakaryopoiesis. Approximately 20% of patients with ITP are refractory to corticosteroids and splenectomy. Recently, pulse high-dose dexamethasone was reported to be effective in the treatment of chronic ITP in adult patients. We treated 9 patients with severe chronic ITP with monthly high-dose dexamethasone. None of …
Authors
Warner M; Wasi P; Couban S; Hayward C; Warkentin T; Kelton JG
Journal
American Journal of Hematology, Vol. 54, No. 4, pp. 267–270
Publisher
Wiley
Publication Date
April 1997
DOI
10.1002/(sici)1096-8652(199704)54:4<267::aid-ajh1>3.0.co;2-t
ISSN
0361-8609