Journal article
Measurement of fibrinogen binding to platelets in whole blood by flow cytometry: a micromethod for the detection of platelet activation
Abstract
Platelet fibrinogen binding in whole blood has been measured in vitro by flow cytometry using a commercially available, fluorescein isothiocyanate (FITC)-conjugated polyclonal antifibrinogen antibody. Fibrinogen-antifibrinogen immune complexes were formed in experimental conditions approaching antigen-antibody equivalence, but optimal reaction conditions in which their formation was prevented or minimized could be achieved. Immune complex …
Authors
Warkentin TE; Powling MJ; Hardisty RM
Journal
British Journal of Haematology, Vol. 76, No. 3, pp. 387–394
Publisher
Wiley
Publication Date
11 1990
DOI
10.1111/j.1365-2141.1990.tb06373.x
ISSN
0007-1048