Journal article
The platelet serotonin‐release assay
Abstract
Few laboratory tests are as clinically useful as The platelet serotonin-release assay (SRA): a positive SRA in the appropriate clinical context is virtually diagnostic of heparin-induced thrombocytopenia (HIT), a life- and limb-threatening prothrombotic disorder caused by anti-platelet factor 4 (PF4)/heparin antibodies that activate platelets, thereby triggering serotonin-release. The SRA's performance characteristics include high sensitivity …
Authors
Warkentin TE; Arnold DM; Nazi I; Kelton JG
Journal
American Journal of Hematology, Vol. 90, No. 6, pp. 564–572
Publisher
Wiley
Publication Date
June 2015
DOI
10.1002/ajh.24006
ISSN
0361-8609