Journal article
Immune heparin‐induced thrombocytopenia can occur in patients receiving clopidogrel and aspirin
Abstract
Platelet adenosine diphosphate (ADP) receptors may play a role in potentiating platelet activation induced by IgG from patients with immune heparin-induced thrombocytopenia (HIT), as shown by previous studies using the ADP receptor antagonists AR-C66096 and ticlopidine. Consistent with these observations, we found that platelet activation by HIT sera is also significantly reduced in patients receiving clopidogrel, an ADP receptor antagonist …
Authors
Selleng K; Selleng S; Raschke R; Schmidt CO; Rosenblood GS; Greinacher A; Warkentin TE
Journal
American Journal of Hematology, Vol. 78, No. 3, pp. 188–192
Publisher
Wiley
Publication Date
March 2005
DOI
10.1002/ajh.20305
ISSN
0361-8609