Anti–protamine-heparin antibodies: incidence, clinical relevance, and pathogenesis Academic Article uri icon

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abstract

  • Key PointsImmunization against protamine/heparin complexes was frequently observed in patients undergoing cardiac surgery. Platelet-activating anti–protamine-heparin antibodies are a potential risk factor for early postoperative thrombosis and thrombocytopenia.

authors

  • Bakchoul, Tamam
  • Zöllner, Heike
  • Amiral, Jean
  • Panzer, Simon
  • Selleng, Sixten
  • Kohlmann, Thomas
  • Brandt, Sven
  • Delcea, Mihaela
  • Warkentin, Ted
  • Sachs, Ulrich J
  • Greinacher, Andreas

publication date

  • April 11, 2013

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