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Warfarin-induced venous limb ischemia/gangrene...
Journal article

Warfarin-induced venous limb ischemia/gangrene complicating cancer: a novel and clinically distinct syndrome

Abstract

Venous limb gangrene (VLG) can occur in cancer patients, but the clinical picture and pathogenesis remain uncertain. We identified 10 patients with metastatic cancer (7 pathologically proven) who developed severe venous limb ischemia (phlegmasia/VLG) after initiating treatment of deep-vein thrombosis (DVT); in 8 patients, cancer was not known or suspected at presentation. The patients exhibited a novel, clinically distinct syndrome: …

Authors

Warkentin TE; Cook RJ; Sarode R; Sloane DA; Crowther MA

Journal

Blood, Vol. 126, No. 4, pp. 486–493

Publisher

American Society of Hematology

Publication Date

July 23, 2015

DOI

10.1182/blood-2015-01-622787

ISSN

0006-4971