Warfarin-induced venous limb ischemia/gangrene complicating cancer: a novel and clinically distinct syndrome Academic Article uri icon

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abstract

  • Key Points Warfarin-induced venous gangrene in cancer affects limb with DVT and features platelet fall after stopping heparin and supratherapeutic INR. Persisting thrombin generation occurs despite elevated INR, indicating severe PC depletion that occurs in parallel with reduced factor VII.

publication date

  • July 23, 2015

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