Fibrin Concept

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• 4D intravital imaging identifies platelets as the predominant cellular procoagulant surface in a mouse hemostasis model  Journal Articles
• In‐Vitro Studies with Ancrod (‘Arvin’)  Journal Articles
• Staphylococcus aureus Fibronectin-Binding Protein Serves as a Substrate for Coagulation Factor XIIIa:  Evidence for Factor XIIIa-Catalyzed Covalent Cross-Linking to Fibronectin and Fibrin  Journal Articles
• A High Affinity Interaction of Plasminogen with Fibrin Is Not Essential for Efficient Activation by Tissue-type Plasminogen Activator  Journal Articles
• Activated platelets form protected zones of adhesion on fibrinogen and fibronectin-coated surfaces.  Journal Articles
• Activated thrombin‐activatable fibrinolysis inhibitor (TAFIa) attenuates fibrin‐dependent plasmin generation on thrombin‐activated platelets  Journal Articles
• Activation of blood coagulation by plaque rupture: Mechanisms and prevention  Journal Articles
• Acute Effects with Reference to Thrombogenicity and Liver Toxicity after Injection of Different Coagulation Factor Concentrates  Journal Articles
• Addition of a sequence from α2-antiplasmin transforms human serum albumin into a blood clot component that speeds clot lysis  Journal Articles
• Angiomatosis of skin with local intravascular immunoglobulin deposits, associated with monoclonal gammopathy. A potential cutaneous marker for B‐chronic lymphocytic leukemia  Journal Articles
• Antithrombin-Heparin Covalent Complex  Journal Articles
• Arachidonate induced fibrinogen binding to thrombin degranulated platelets is independent of released ADP  Other
• Are There Patients With Acute Ischemic Stroke and Atrial Fibrillation That Benefit From Low Molecular Weight Heparin?  Journal Articles
• Assays to quantify fibrinolysis: strengths and limitations. Communication from the International Society on Thrombosis and Haemostasis Scientific and Standardization Committee on fibrinolysis  Journal Articles
• Bioregulatory roles for fibrin(ogen) on blood coagulation  Journal Articles
• Bivalent Binding to γA/γ′-Fibrin Engages Both Exosites of Thrombin and Protects It from Inhibition by the Antithrombin-Heparin Complex  Journal Articles
• Blood tests for the diagnosis of venous and arterial thrombosis  Journal Articles
• By Increasing the Affinity of Heparin for Fibrin, Zn²⁺ Promotes the Formation of a Ternary Heparin–Thrombin–Fibrin Complex That Protects Thrombin from Inhibition by Antithrombin  Journal Articles
• Cell-Free DNA Modulates Clot Structure and Impairs Fibrinolysis in Sepsis  Journal Articles
• Cerebral Venous Thrombosis During Pregnancy in the Setting of Type I Antithrombin Deficiency: Case Report and Literature Review  Journal Articles
• Characterization of a Mouse Model for Thrombomodulin Deficiency  Journal Articles
• Characterization of the Interactions of Plasminogen and Tissue and Vampire Bat Plasminogen Activators with Fibrinogen, Fibrin, and the Complex of d-Dimer Noncovalently Linked to Fragment E  Journal Articles
• Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors.  Journal Articles
• Combined administration of barbourin–albumin and hirudin–albumin fusion proteins limits fibrin(ogen) deposition on the rabbit balloon-injured aorta  Journal Articles
• Composition and characteristics of an autologous thrombocyte gel  Journal Articles
• Conformational Changes in Thrombin When Complexed by Serpins  Journal Articles
• Cutaneous collagenous vasculopathy associated with intravascular occlusive fibrin thrombi  Journal Articles
• Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function  Journal Articles
• Decreased Thrombin Activity of Fibrin Clots Prepared in Cord Plasma Compared with Adult Plasma  Journal Articles
• Direct Thrombin Inhibitors in Acute Coronary Syndromes  Journal Articles
• Displacement of Fibrin-bound Thrombin by r-Hirudin Precludes the Use of 131l-r-Hirudin for Detecting Pulmonary Emboli in the Rabbit  Journal Articles
• Disseminated Intravascular Coagulation [Abridged]  Journal Articles
• EXPERIMENTAL PRODUCTION OF MICROANGIOPATHIC HÆMOLYTIC ANÆMIA IN VIVO  Journal Articles
• Effect of Streptokinase on Hemostasis  Journal Articles
• Effect of endothelium on the anticoagulant activity of a covalent antithrombin-heparin complex.  Journal Articles
• Effect of streptokinase therapy on experimental fibrin-rich arterial thrombi.  Journal Articles
• Effect of substrate and fibrin polymerization inhibitor on determination of plasma thrombin generation in vitro  Journal Articles
• Effects of Dermatan Sulfate and Heparin on Inhibition of Thrombus Growth in Vivo  Journal Articles
• Effects of heparin, its low molecular weight fractions and other glycosaminoglycans on thrombus growth  Journal Articles
• Evaluation of a Soluble Fibrin Assay in Patients with Suspected Pulmonary Embolism  Journal Articles
• Evaluation of a soluble fibrin assay in patients with suspected deep vein thrombosis.  Journal Articles
• Evaluation of the Combination of a Bedside D-Dimer Assay and Enzyme-Linked Immunosorbent Soluble Fibrin Assay in Patients with Suspected Venous Thromboembolism  Journal Articles
• Evidence That Both Exosites on Thrombin Participate in Its High Affinity Interaction with Fibrin  Journal Articles
• Exosites 1 and 2 Are Essential for Protection of Fibrin-bound Thrombin from Heparin-catalyzed Inhibition by Antithrombin and Heparin Cofactor II  Journal Articles
• Factor XIIIa Mediated Attachment of S. aureus Fibronectin-Binding Protein A (FnbA) to Fibrin:  Identification of Gln103 as a Major Cross-Linking Site  Journal Articles
• Factors Influencing the Deaggregation of Human and Rabbit Platelets  Journal Articles
• Fgl2 prothrombinase expression in mouse trophoblast and decidua triggers abortion but may be countered by OX-2  Journal Articles
• Fibrin Clot Lysis by Thrombolytic Agents Is Impaired in Newborns due to a Low Plasminogen Concentration  Journal Articles
• Fibrin biomatrix-conjugated platelet-derived growth factor AB accelerates wound healing in severe thermal injury  Journal Articles
• Fibrin moderates the catalytic action of heparin but not that of dermatan sulfate on thrombin inhibition in human plasma.  Journal Articles
• Fibrinogen Catabolism in Microangiopathic Haemolytic Anaemia  Journal Articles
• Handheld instrument for wound-conformal delivery of skin precursor sheets improves healing in full-thickness burns  Journal Articles
• Hemophilia and von Willebrand's disease: 2. Management. Association of Hemophilia Clinic Directors of Canada.  Journal Articles
• Heparan sulfate: Antithrombotic or not?  Journal Articles
• Histidine-Rich Glycoprotein Modulates the Toxic Effects of High-Dose Polyphosphate in Mice  Journal Articles
• Histidine-rich Glycoprotein Binds Fibrin(ogen) with High Affinity and Competes with Thrombin for Binding to the γ′-Chain  Journal Articles
• Human ovarian cancer ascites fluid contains a mixture of incompletely degraded soluble products of fibrin that collectively possess an antiangiogenic property  Journal Articles
• Hypercoagulability.  Journal Articles
• INTRAVASCULAR HÆMOLYSIS AND DISSEMINATED INTRAVASCULAR COAGULATION  Journal Articles
• Identification of the Mechanism Responsible for the Increased Fibrin Specificity of TNK-Tissue Plasminogen Activator Relative to Tissue Plasminogen Activator  Journal Articles
• In vitro and ex vivo Activities of CY216: Comparison with Other Low Molecular Weight Heparins  Journal Articles
• In vivo rabbit acute model tests of polyurethane catheters coated with a novel antithrombin-heparin covalent complex  Journal Articles
• Incorporation of Fragment X into Fibrin Clots Renders Them More Susceptible to Lysis by Plasmin  Journal Articles
• Incorporation of Vitronectin into Fibrin Clots  Journal Articles
• Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa  Journal Articles
• Influence of Mechanical Stretch on Thrombin Regulation by Fetal Mixed Lung Cells  Journal Articles
• Inhibition of Fibrin-Bound Thrombin by a Covalent Antithrombin-Heparin Complex  Journal Articles
• Inhibition of the prothrombinase complex on red blood cells by heparin and covalent antithrombin-heparin complex  Journal Articles
• Interactions of heparin and a covalently-linked antithrombin-heparin complex with components of the fibrinolytic system  Journal Articles
• Intimal alterations in rabbit aortas during the first 6 months of alloxan-induced diabetes.  Journal Articles
• Investigation of the Mechanism of False Positive ¹²⁵I‐Labelled Fibrinogen Scans  Journal Articles
• Leukocyte urokinase plasminogen activator receptor and PSGL1 play a role in endogenous arterial fibrinolysis  Journal Articles
• Like Fibrin, (DD)E, the Major Degradation Product of Crosslinked Fibrin, Protects Plasmin from Inhibition by α2-antiplasmin  Journal Articles
• Limited Fibrin Specificity of Tissue-type Plasminogen Activator and Its Potential Link to Bleeding  Journal Articles
• Long Range Communication between Exosites 1 and 2 Modulates Thrombin Function  Journal Articles
• Lysis of surface-localized fibrin clots by adsorbed plasminogen in the presence of tissue plasminogen activator  Journal Articles
• Massive perivillous fibrinoid causing recurrent placental failure  Journal Articles
• Mechanisms for elevated fibrin/fibrinogen degradation products in acute experimental pulmonary embolism  Journal Articles
• Microangiopathic Haemolytic Anaemia: Mechanisms of Red‐Cell Fragmentation: in Vitro Studies  Journal Articles
• Microangiopathic Haemolytic Anaemia: the Experimental Production of Haemolysis and Red‐Cell Fragmentation by Defibrination in Vivo  Journal Articles
• Microangiopathic haemolytic anaemia: experimental production of fragmented erythrocytes in vitro.  Journal Articles
• Modes and consequences of thrombin's interaction with fibrin  Journal Articles
• Modulation of intrinsic prothrombin activation by fibrinogen and fibrin I.  Journal Articles
• Molecular Basis for the Resistance of Fibrin-Bound Thrombin to Inactivation by Heparin/Serpin Complexes  Journal Articles
• Molecular Basis for the Susceptibility of Fibrin-bound Thrombin to Inactivation by Heparin Cofactor II in the Presence of Dermatan Sulfate but Not Heparin  Journal Articles
• New anticoagulant strategies.  Journal Articles
• Non‐Steroidal Anti‐Inflammatory Agents and Coronary Heart Disease  Journal Articles
• Organ Distribution of Fibrin in Disseminated Intravascular Coagulation  Journal Articles
• Pericapillary fibrin deposits and skin hypoxia precede the changes of lipodermatosclerosis in limbs at increased risk of developing a venous ulcer.  Journal Articles
• Phosphatidylinositol 4,5-bisphosphate is selectively retained by platelet-fibrin clots formed by thrombin  Journal Articles
• Phosphatidylserine externalization and procoagulant activation of erythrocytes induced by Pseudomonas aeruginosa virulence factor pyocyanin  Journal Articles
• Plasma fibronectin supports hemostasis and regulates thrombosis  Journal Articles
• Platelet Accumulation on Fibrin-coated Polyethylene: Role of Platelet Activation and Factor XIII \textbar Request PDF  Journal Articles
• Polymerizing Fibrin Decreases the Polyphosphoinositides in Chymotrypsin‐Treated Human Platelets  Journal Articles
• Polyphosphate colocalizes with factor XII on platelet-bound fibrin and augments its plasminogen activator activity  Journal Articles
• RE: The prothrombin time ratio is not a more effective marker for evaluating sepsis‐induced coagulopathy than fibrin‐related markers: Response to the Letter‐to‐the‐Editor by Dr Wada  Journal Articles
• RED-BLOOD-CELL FRAGMENTATION IN MICROANGIOPATHIC HÆMOLYTIC ANÆMIA: IN-VITRO STUDIES  Journal Articles
• Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse  Journal Articles
• Reduced Plasminogen Binding and Delayed Activation Render γ′-Fibrin More Resistant to Lysis than γA-Fibrin  Journal Articles
• Relationship of Metabolic Syndrome and Fibrinolytic Dysfunction to Cardiovascular Disease  Journal Articles
• Soluble fibrin degradation products potentiate tissue plasminogen activator-induced fibrinogen proteolysis.  Journal Articles
• Strain history dependence of the nonlinear stress response of fibrin and collagen networks  Journal Articles
• Sustained antithrombotic activity of hirudin after its plasma clearance: comparison with heparin  Journal Articles
• The Coagulation System in Humans  Journal Articles
• The Effect of Antithrombin III-Independent Thrombin Inhibitors and Heparin on Fibrin Accretion onto Fibrin-Coated Polyethylene \textbar Request PDF  Journal Articles
• The Role of Protected Extracellular Compartments in Interactions between Leukocytes, and Platelets, and Fibrin/Fibrinogen Matricesa  Journal Articles
• The Transferable Tail:  Fusion of the N-Terminal Acidic Extension of Heparin Cofactor II to α₁-Proteinase Inhibitor M358R Specifically Increases the Rate of Thrombin Inhibition  Journal Articles
• The benefit-to-risk profile of melagatran is superior to that of hirudin in a rabbit arterial thrombosis prevention and bleeding model  Journal Articles
• The mechanism of action of thrombin inhibitors.  Journal Articles
• The proteolytic action of Arvin on human fibrinogen  Journal Articles
• The relation among vessel injury, thrombus formation, and platelet survival in rabbits  Journal Articles
• The relative kinetics of clotting and lysis provide a biochemical rationale for the correlation between elevated fibrinogen and cardiovascular disease  Journal Articles
• Thrombin Generation  Journal Articles
• Thrombin generation and fibrin formation following injury to rabbit neointima. Studies of vessel wall reactivity and platelet survival  Other
• Thrombin-activable Fibrinolysis Inhibitor Attenuates (DD)E-mediated Stimulation of Plasminogen Activation by Reducing the Affinity of (DD)E for Tissue Plasminogen Activator  Journal Articles
• Thrombin-activatable fibrinolysis inhibitor and sex modulate thrombus stability and pulmonary embolism burden in a murine model  Journal Articles
• Thrombocytopenia in Preeclampsia and Eclampsia  Journal Articles
• Thrombogenic Effect of High-Dose Aspirin in Rabbits  Journal Articles
• Thrombus formation: direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy  Journal Articles
• Type 1 Plasminogen Activator Inhibitor Binds to Fibrin via Vitronectin  Journal Articles
• Vasoflux, a New Anticoagulant With a Novel Mechanism of Action  Journal Articles
• Zinc delays clot lysis by attenuating plasminogen activation and plasmin-mediated fibrin degradation  Journal Articles
• Zinc promotes clot stability by accelerating clot formation and modifying fibrin structure  Journal Articles
• Zn2+ Mediates High Affinity Binding of Heparin to the αC Domain of Fibrinogen  Journal Articles