Journal article
Human ovarian cancer ascites fluid contains a mixture of incompletely degraded soluble products of fibrin that collectively possess an antiangiogenic property
Abstract
Ovarian cancer ascites fluid (OCAF) displayed an antiangiogenic property in a chick chorioallantoic membrane (CAM) assay. This property was attributed in part to angiostatin although angiostatin-free OCAF retained a net antiangiogenic property. Recently, immunopurified fibrin(ogen) degradation products (FDPs) from malignant effusions of VX2 tumor-burdened rabbits exhibited antiangiogenic activity on the CAM. We questioned whether the FDPs of …
Authors
JANDU N; RICHARDSON M; SINGH G; HIRTE H; HATTON MWC
Journal
International Journal of Gynecological Cancer, Vol. 16, No. 4, pp. 1536–1544
Publisher
Elsevier
Publication Date
July 2006
DOI
10.1111/j.1525-1438.2006.00624.x
ISSN
1048-891X