Journal article
Fibrin biomatrix‐conjugated platelet‐derived growth factor AB accelerates wound healing in severe thermal injury
Abstract
Controlled delivery of growth factors from biodegradable biomatrices could accelerate and improve impaired wound healing. The study aim was to determine whether platelet-derived growth factor AB (PDGF.AB) with a transglutaminase (TG) crosslinking substrate site released from a fibrin biomatrix improves wound healing in severe thermal injury. The binding and release kinetics of TG-PDGF.AB were determined in vitro. Third-degree contact burns …
Authors
Mittermayr R; Branski L; Moritz M; Jeschke MG; Herndon DN; Traber D; Schense J; Gampfer J; Goppelt A; Redl H
Journal
Journal of Tissue Engineering and Regenerative Medicine, Vol. 10, No. 5, pp. e275–e285
Publisher
Hindawi
Publication Date
May 2016
DOI
10.1002/term.1749
ISSN
1932-6254