Journal article
Fibrin Clot Lysis by Thrombolytic Agents Is Impaired in Newborns due to a Low Plasminogen Concentration
Abstract
Although thrombolytic drugs have been extensively used in adults, there is sparse information on their effectiveness in newborns whose fibrinolytic system differs significantly from adults. The purpose of this study was to determine if low plasma levels of plasminogen in cord plasma limited the therapeutic effectiveness of thrombolytic agents. Urokinase (UK), streptokinase (SK) and tissue plasminogen activator (TPA) were compared for their …
Authors
Andrew M; Brooker L; Leaker M; Paes B; Weitz J
Journal
Thrombosis and Haemostasis, Vol. 68, No. 03, pp. 325–330
Publisher
Thieme
Publication Date
1992
DOI
10.1055/s-0038-1656374
ISSN
0340-6245