Polyphosphate colocalizes with factor XII on platelet-bound fibrin and augments its plasminogen activator activity Academic Article uri icon

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abstract

  • Key Points PolyP significantly augments the plasminogen activator capacity of FXIIa. Platelet-bound fibrin acts as a reservoir for plasminogen, FXII(a), and polyP.

authors

  • Mitchell, Joanne L
  • Lionikiene, Ausra S
  • Georgiev, Georgi
  • Klemmer, Anja
  • Brain, Chelsea
  • Kim, Paul
  • Mutch, Nicola J

publication date

  • December 15, 2016

published in