Journal article
Acute Effects with Reference to Thrombogenicity and Liver Toxicity after Injection of Different Coagulation Factor Concentrates
Abstract
In order to assess thrombogenicity and liver toxicity of different coagulation factor concentrates, antithrombin III, soluble fibrin, alanine aminotransferase (ALAT) and gamma-glutamyl transpeptidase (GT) were measured in samples taken before, 30 min and 24 h after the infusion. Seventy-six studies were performed in 55 patients with haemophilia A (37), B (11) or von Willebrand's disease, type III (7). A sharp rise of soluble fibrin was observed …
Authors
Schulman S; Johnsson H; Wiman B
Journal
Pathophysiology of Haemostasis and Thrombosis, Vol. 19, No. 3, pp. 152–159
Publisher
Karger Publishers
Publication Date
1989
DOI
10.1159/000215909
ISSN
1424-8832