Cisplatin Concept

subject area of

• N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor  Academic Article
• A New Series of Succinimido-ferrociphenols and Related Heterocyclic Species Induce Strong Antiproliferative Effects, Especially against Ovarian Cancer Cells Resistant to Cisplatin  Academic Article
• A Phase I Study of Pomalidomide (CC-4047) in Combination with Cisplatin and Etoposide in Patients with Extensive-Stage Small-Cell Lung Cancer  Academic Article
• A Suggested Prognostic Reclassification of Intermediate and Poor-Risk Nonseminomatous Germ Cell Tumors  Academic Article
• A Suggested Prognostic Reclassification of Intermediate and Poor-Risk Nonseminomatous Germ Cell Tumors  Academic Article
• A combination of MSH2 DNA mismatch repair deficiency and expression of the SV40 large T antigen results in cisplatin resistance of mouse embryonic fibroblasts  Academic Article
• A phase I study of OSI-211 and cisplatin as intravenous infusions given on days 1, 2 and 3 every 3 weeks in patients with solid cancers  Academic Article
• A phase IB study of durvalumab with or without tremelimumab and platinum-doublet chemotherapy in advanced solid tumours: Canadian Cancer Trials Group Study IND226  Academic Article
• A pilot study using 99mTc to measure lead and platinum in the human kidney  Academic Article
• A possible cellular mechanism of cisplatin-induced nephrotoxicity  Academic Article
• A predictive index of cure versus no cure in advanced ovarian carcinoma patients—Replacement of second-look laparotomy as a diagnostic test  Academic Article
• A single-institution experience of salvage therapy for patients with early and locally advanced breast cancer who progress during neoadjuvant chemotherapy  Academic Article
• Adjuvant Systemic Therapy and Adjuvant Radiation Therapy for Stage I to IIIA Completely Resected Non–Small-Cell Lung Cancers: American Society of Clinical Oncology/Cancer Care Ontario Clinical Practice Guideline Update  Academic Article
• Adjuvant chemotherapy for upper-tract urothelial carcinoma treated with nephroureterectomy: Assessment of adequate renal function and influence on outcome  Academic Article
• Adjuvant sunitinib following chemoradiotherapy and surgery for locally advanced esophageal cancer: a phase II trial  Academic Article
• Adjuvant therapy for resected non-small-cell lung cancer: Past, present, and future  Academic Article
• Adriamycin and cisplatin in the treatment of stage III and IV epithelial ovarian carcinoma  Academic Article
• Advanced Ovarian Cancer: Phase III Randomized Study of Sequential Cisplatin–Topotecan and Carboplatin–Paclitaxel vs Carboplatin–Paclitaxel  Academic Article
• Agave negatively regulates YAP and TAZ transcriptionally and post-translationally in osteosarcoma cell lines  Academic Article
• Anti-proliferative and chemosensitizing effects of luteolin on human gastric cancer AGS cell line  Academic Article
• Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression  Academic Article
• Association of Urine Platinum With Acute Kidney Injury in Children Treated With Cisplatin for Cancer  Academic Article
• Bax Homodimerization Is Not Required for Bax to Accelerate Chemotherapy-induced Cell Death  Academic Article
• Better Treatments That Cost More: The Dilemma  Academic Article
• Canadian Cancer Trials Group (CCTG) IND215: A phase Ib study of Selumetinib in patients with untreated advanced or metastatic NSCLC who are receiving standard chemotherapy regimens  Academic Article
• Cancer Care Ontario and American Society of Clinical Oncology Adjuvant Chemotherapy and Adjuvant Radiation Therapy for Stages I-IIIA Resectable Non–Small-Cell Lung Cancer Guideline  Academic Article
• Candidemia in women with breast carcinoma treated with high-dose chemotherapy and autologous bone marrow transplantation  Academic Article
• Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain  Academic Article
• Chemoradiotherapy with or without panitumumab in patients with unresected, locally advanced squamous-cell carcinoma of the head and neck (CONCERT-1): a randomised, controlled, open-label phase 2 trial  Academic Article
• Chemotherapy agents and the induction of late lethal defects.  Academic Article
• Chemotherapy can prolong survival in patients with advanced non-small-cell lung cancer--report of a Canadian multicenter randomized trial.  Academic Article
• Chemotherapy of advanced ovarian carcinoma: Initial experience using a platinum-based combination  Academic Article
• Chemotherapy with gemcitabine-containing regimens for locally recurrent or metastatic nasopharyngeal carcinoma  Academic Article
• Childhood Atypical Teratoid Rhabdoid Tumor of the Central Nervous System  Academic Article
• Choices of Methodology in Pharmacoeconomic Studies  Academic Article
• Cisplatin- Versus Non–Cisplatin-based First-Line Chemotherapy for Advanced Urothelial Carcinoma Previously Treated With Perioperative Cisplatin  Academic Article
• Cisplatin-Based First-Line Therapy for Advanced Urothelial Carcinoma After Previous Perioperative Cisplatin-Based Therapy  Academic Article
• Cisplatin-modification of DNA repair and ionizing radiation lethality in yeast, Saccharomyces cerevisiae  Academic Article
• Combination chemotherapy with bleomycin, etoposide, and cisplatin in metastatic non-small-cell lung cancer.  Academic Article
• Combined chemotherapy and radiation therapy for non-small-cell lung cancer.  Academic Article
• Combined gamma‐irradiation and subsequent cisplatin treatment in human squamous carcinoma cell lines sensitive and resistant to cisplatin  Academic Article
• Concurrent Cisplatin-based Chemotherapy plus Radiotherapy for Cervical Cancer:  Academic Article
• Concurrent Cisplatin-based Chemotherapy plus Radiotherapy for Cervical Cancer–a Meta-analysis  Academic Article
• Cross-resistance to cisplatin in cells resistant to photofrin-mediated photodynamic therapy.  Academic Article
• Cyclophosphamide, doxorubicin, and cisplatin in the treatment of non-small cell bronchogenic carcinoma.  Academic Article
• DIFFERENTIAL SENSITIVITY TO SHORT-CHAIN CERAMIDE ANALOGUES OF HUMAN INTESTINAL CARCINOMA CELLS GROWN IN TUMOR SPHEROIDS VERSUS MONOLAYER CULTURE  Academic Article
• Dexamethasone improves the efficacy of granisetron in the first 24 h following high-dose cisplatin chemotherapy  Academic Article
• Differential Toxicity of Cis andTrans Isomers of Dichlorodiammineplatinum  Academic Article
• Differential effects of cisplatin on mouse hepatic and renal mitochrondrial DNA  Academic Article
• ECF in gastric cancer  Academic Article
• Effect of ERCC-1 overexpression on sensitivity of Chinese hamster ovary cells to DNA damaging agents.  Academic Article
• Endodermal Sinus Tumor in Pregnancy  Academic Article
• Energetic characteristics of cisplatin resistant ovarian carcinoma cells.  Academic Article
• Ethical communication in clinical trials  Academic Article
• Evidence for a dose-response effect between p53 (but not p21WAF1/Cip1) protein concentrations, survival, and responsiveness in patients with epithelial ovarian cancer treated with platinum-based chemotherapy.  Conference Paper
• Evidence for lack of mitochondrial DNA repair followingcis-dichlorodiammineplatinum treatment  Academic Article
• Exogenous estrogen therapy, testicular cancer, and the male to female transgender population: a case report  Academic Article
• Expression of survivin and p16INK4a/Cdk6/pRB proteins and induction of apoptosis in response to radiation and cisplatin in meningioma cells  Academic Article
• First-Line Systemic Chemotherapy in the Treatment of Advanced Non-small Cell Lung Cancer: A Systematic Review  Academic Article
• Five-Factor Prognostic Model for Survival of Post-Platinum Patients with Metastatic Urothelial Carcinoma Receiving PD-L1 Inhibitors  Academic Article
• Flavopiridol Sensitivity of Cancer Cells Isolated from Ascites and Pleural Fluids  Academic Article
• Gemcitabine, dexamethasone and cisplatin is an active andnon-toxic chemotherapy regimen in relapsed or refractory Hodgkin’s disease: a phase II study by the National Cancer Institute of Canada Clinical Trials Group  Academic Article
• Gemcitabine, dexamethasone, and cisplatin in patients with recurrent or refractory aggressive histology B-cell non-Hodgkin lymphoma  Academic Article
• Gemcitabine/Dexamethasone/Cisplatin vs Cytarabine/Dexamethasone/Cisplatin for Relapsed or Refractory Aggressive-Histology Lymphoma: Cost-Utility Analysis of NCIC CTG LY.12  Academic Article
• Guideline for the Initial Management of Small Cell Lung Cancer (Limited and Extensive Stage) and the Role of Thoracic Radiotherapy and First-line Chemotherapy  Academic Article
• HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function  Academic Article
• HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome  Academic Article
• Human cells deficient in transcription-coupled repair show prolonged activation of the Jun N-terminal kinase and increased sensitivity following cisplatin treatment  Academic Article
• IL‐25 promotes cisplatin resistance of lung cancer cells by activating NF‐κB signaling pathway to increase of major vault protein  Academic Article
• Ifosfamide and mesna in combination with other cytostatic drugs in the treatment of patients with advanced cancer  Academic Article
• Inconsistency of prognostic factors for post-chemotherapy nausea and vomiting  Academic Article
• Increased BNip3 and decreased mutant p53 in cisplatin-sensitive PDT-resistant HT29 cells  Academic Article
• Indirect comparison of the efficacy of cetuximab and cisplatin in squamous cell carcinoma of the head and neck  Academic Article
• Induction chemotherapy with paclitaxel and cisplatin followed by radiotherapy for larynx organ preservation in advanced laryngeal and hypopharyngeal cancer offers moderate late toxicity outcome (DeLOS-I-trial)  Academic Article
• Induction of Mdm2 and enhancement of cell survival by bFGF  Academic Article
• Induction of micronucleated and binucleate cells in Chinese hamster ovary (CHO) cells by cis-diamminedichloroplatinum (II): a morphological and morphometric study  Academic Article
• Influence of the proto-oncogene c-fos on cisplatin sensitivity  Academic Article
• Inhibition of RNA polymerase II as a trigger for the p53 response  Academic Article
• Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin  Academic Article
• Initial Management of Small-Cell Lung Cancer (limited- and Extensive-Stage) and the Role of Thoracic Radiotherapy and First-Line Chemotherapy: A Systematic Review  Academic Article
• Interactions of doxycycline with chemotherapeutic agents in human breast adenocarcinoma MDA-MB-231 cells  Academic Article
• Investigating and addressing the immediate and long-term consequences of the COVID-19 pandemic on patients with substance use disorders: a scoping review and evidence map protocol  Academic Article
• Lack of correlation of P-glycoprotein expression with response to MIC chemotherapy in oesophageal cancer.  Academic Article
• Low-grade serous carcinoma (LGSC): A Canadian multicenter review of practice patterns and patient outcomes  Conference Paper
• MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function  Academic Article
• Modulation of radiation-induced strand break repair by cisplatin in mammalian cells  Academic Article
• Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy  Academic Article
• Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression  Academic Article
• NCIC CTG IND.190 Phase I Trial of Dalotuzumab (MK-0646) in Combination with Cisplatin and Etoposide in Extensive-Stage Small-Cell Lung Cancer  Academic Article
• Naturally occurring resistance of bone marrow mononuclear and metastatic cancer cells to anticancer agents  Academic Article
• Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance  Academic Article
• Nivolumab in Combination With Platinum‐Based Doublet Chemotherapy for First-Line Treatment of Advanced Non–Small-Cell Lung Cancer  Academic Article
• Nucleotide excision repair in the human ovarian carcinoma cell line (2008) and its cisplatin-resistant variant (C13*)  Academic Article
• Optimal pathological response after neoadjuvant chemotherapy for muscle‐invasive bladder cancer: results from a global, multicentre collaboration  Academic Article
• Outcomes in Patients With Clinical Stage III NSGCT Who Achieve Complete Clinical Response to Chemotherapy at Extraretroperitoneal Disease Site  Academic Article
• PML, YAP, and p73 Are Components of a Proapoptotic Autoregulatory Feedback Loop  Academic Article
• Paclitaxel and cisplatin as intravesical agents against non-muscle-invasive bladder cancer  Academic Article
• Paraspinal Synovial Sarcoma as an Unusual Postradiation Complication in Pediatric Abdominal Neuroblastoma  Academic Article
• Patient preferences for oropharyngeal cancer treatment de-escalation  Academic Article
• Patients’ Preferences for Therapy in Advanced Epithelial Ovarian Cancer: Development, Testing, and Application of a Bedside Decision Instrument  Academic Article
• Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial  Academic Article
• Perioperative DCF chemotherapy protocol for patients with gastroesophageal adenocarcinoma: correlation between response to treatment and outcome  Academic Article
• Perioperative docetaxel, cisplatin, and 5-fluorouracil (DCF) for locally advanced esophageal and gastric adenocarcinoma: a multicenter phase II trial  Academic Article
• Phase I Trial of Granulocyte-Macrophage Colony-Stimulating Factor With High-Dose Cisplatin and Etoposide for Treatment of Small-Cell Lung Cancer: A Study of the National Cancer Institute of Canada Clinical Trials Group  Academic Article
• Phase I trial of gemcitabine, doxorubicin and cisplatin (GAP) in patients with advanced solid tumors  Academic Article
• Phase I/II Trial of Erlotinib and Cisplatin in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: A Princess Margaret Hospital Phase II Consortium and National Cancer Institute of Canada Clinical Trials Group Study  Conference Paper
• Phase II Study of Concurrent Pemetrexed, Cisplatin, and Radiation Therapy for Stage IIIA/B Unresectable Non–Small Cell Lung Cancer  Academic Article
• Phase II Study to Evaluate the Toxicity and Efficacy of Concurrent Cisplatin and Radiation Therapy in the Treatment of Patients with Locally Advanced Squamous Cell Carcinoma of the Cervix  Academic Article
• Phase II study of mitomycin C and 5 fluorouracil in platinum resistant ovarian cancer.  Academic Article
• Phase II study of pemetrexed disodium, a multitargeted antifolate, and cisplatin as first-line therapy in patients with advanced nonsmall cell lung carcinoma  Academic Article
• Phase II trial evaluating continuous infusion of etoposide, cisplatin, and hexamethylmelamine in extensive-disease small cell carcinoma of the lung.  Academic Article
• Phase III Study of Pemetrexed in Combination With Cisplatin Versus Cisplatin Alone in Patients With Malignant Pleural Mesothelioma  Academic Article
• Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix.  Academic Article
• Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dL with erythropoietin vs above 10.0 g/dL without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer  Academic Article
• Posttreatment prognostic nomogram for patients with metastatic urothelial cancer completing first-line cisplatin-based chemotherapy  Academic Article
• Pre-exposure of human squamous carcinoma cells to low-doses of gamma-rays leads to an increased resistance to subsequent low-dose cisplatin treatment  Academic Article
• Quality of life and swallowing with standard chemoradiotherapy versus accelerated radiotherapy and panitumumab in locoregionally advanced carcinoma of the head and neck: A phase III randomised trial from the Canadian Cancer Trials Group (HN.6)  Academic Article
• Randomized Comparison of Gemcitabine, Dexamethasone, and Cisplatin Versus Dexamethasone, Cytarabine, and Cisplatin Chemotherapy Before Autologous Stem-Cell Transplantation for Relapsed and Refractory Aggressive Lymphomas: NCIC-CTG LY.12  Academic Article
• Randomized Phase II Study of Gemcitabine Plus Cisplatin or Carboplatin, With or Without Cetuximab, As First-Line Therapy for Patients With Advanced or Metastatic Non–Small-Cell Lung Cancer  Conference Paper
• Randomized Phase III Trial Comparing Irinotecan/Cisplatin With Etoposide/Cisplatin in Patients With Previously Untreated Extensive-Stage Disease Small-Cell Lung Cancer  Conference Paper
• Randomized, double-blind, placebo-controlled trial comparing the response rates of carmustine, dacarbazine, and cisplatin with and without tamoxifen in patients with metastatic melanoma  Academic Article
• Randomized, double-blind, placebo-controlled trial comparing the response rates of carmustine, dacarbazine, and cisplatin with and without tamoxifen in patients with metastatic melanoma. National Cancer Institute of Canada Clinical Trials Group.  Academic Article
• Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth  Academic Article
• Relation between platinum-DNA adducts and complete remission in adult acute nonlymphocytic leukemia  Academic Article
• Responsiveness of Intrinsic Subtypes to Adjuvant Anthracycline Substitution in the NCIC.CTG MA.5 Randomized Trial  Academic Article
• Risk of Acute Leukemia Following Epirubicin-Based Adjuvant Chemotherapy: A Report From the National Cancer Institute of Canada Clinical Trials Group  Academic Article
• Risk of Menopause During the First Year After Breast Cancer Diagnosis  Academic Article
• Roberts syndrome fibroblasts showing cisplatin hypersensitivity have normal host cell reactivation of cisplatin-treated adenovirus and normal capacity of cisplatin-treated cells for adenovirus DNA synthesis  Academic Article
• Rolapitant improves quality of life of patients receiving highly or moderately emetogenic chemotherapy  Academic Article
• Role of the transcription factor Ets-1 in cisplatin resistance  Academic Article
• S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation  Academic Article
• Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of cisplatin-based highly emetogenic chemotherapy in patients with cancer: two randomised, active-controlled, double-blind, phase 3 trials  Academic Article
• Salvage chemotherapy and autologous stem cell transplantation for peripheral T-cell lymphoma: a subset analysis of the Canadian Cancer Trials Group LY.12 randomized phase 3 study  Academic Article
• Salvage chemotherapy and autologous stem cell transplantation for transformed indolent lymphoma: a subset analysis of NCIC CTG LY12  Academic Article
• Salvage surgery after induction chemotherapy with paclitaxel/cisplatin and primary radiotherapy for advanced laryngeal and hypopharyngeal carcinomas  Academic Article
• Second-line chemotherapy of stage III-IV ovarian carcinoma: a randomized comparison of melphalan to melphalan and hexamethylmelamine in patients with persistent disease after doxorubicin and cisplatin.  Academic Article
• Significance of Co-expression of Epidermal Growth Factor Receptor and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiotherapy: An Analysis of NRG Oncology RTOG 9811  Conference Paper
• Spindle epithelial tumor with thymus-like elements of the thyroid: a multi-institutional case series and review of the literature  Academic Article
• Superiority of Alternating Non-Cross-Resistant Chemotherapy in Extensive Small Cell Lung Cancer  Academic Article
• Synthesis, characterization, structure, molecular modeling studies and biological activity of sterically crowded Pt(II) complexes containing bis(imidazole) ligands  Academic Article
• Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy  Academic Article
• Taxanes as first-line therapy for advanced non-small cell lung cancer: A systematic review and practice guideline  Academic Article
• The Cancer-associated K351N Mutation Affects the Ubiquitination and the Translocation to Mitochondria of p53 Protein  Academic Article
• The Effect of Radiation and Cytotoxic Platinum Compounds on the Growth of Normal and Tumour Bladder Explant Cultures  Academic Article
• The Effects of Cisplatin on Normal Human Erythrocytes in Vitro  Academic Article
• The Thrombospondin-1 Mimetic ABT-510 Increases the Uptake and Effectiveness of Cisplatin and Paclitaxel in a Mouse Model of Epithelial Ovarian Cancer  Academic Article
• The Transcriptional Coactivator Yes-Associated Protein Drives p73 Gene-Target Specificity in Response to DNA Damage  Academic Article
• The Use of Chemotherapy in Patients with Advanced Malignant Pleural Mesothelioma: A Systematic Review and Practice Guideline  Academic Article
• The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites  Academic Article
• The disruption of the protein complex mutantp53/p73 increases selectively the response of tumor cells to anticancer drugs  Academic Article
• The evidence for tamoxifen and chemotherapy as treatment for metastatic melanoma  Academic Article
• The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway  Academic Article
• The use of VP-16 plus cisplatin during induction chemotherapy for small-cell lung cancer.  Academic Article
• Thromboembolic events in patients with urothelial carcinoma undergoing neoadjuvant chemotherapy and radical cystectomy  Academic Article
• Tirapazamine with cisplatin in patients with advanced non-small-cell lung cancer: a phase II study.  Academic Article
• Tolerance of Radiotherapy and Chemotherapy in Elderly Patients With Bladder Cancer  Academic Article
• Treatment of early epithelial ovarian cancer with chemotherapy and abdominopelvic radiotherapy: results of a prospective treatment protocol  Conference Paper
• Tumor Cavitation: Impact on Objective Response Evaluation in Trials of Angiogenesis Inhibitors in Non–Small-Cell Lung Cancer  Academic Article
• UNEXPECTED MOBILISATION OF LEAD DURING CISPLATIN CHEMOTHERAPY  Academic Article
• Unresected stage III non-small-cell lung cancer. Provincial Lung Cancer Disease Site Group.  Academic Article
• Upper Tract Urothelial Carcinomas: Prognostic Factors and Outcomes in Patients With Non–Lymph Node Distant Metastasis  Academic Article
• Urine biomarkers of acute kidney injury in noncritically ill, hospitalized children treated with chemotherapy  Academic Article
• Urothelial Bladder Cancer with Cavitary Lung Metastases  Academic Article
• Use of dexamethasone and granisetron in the control of delayed emesis for patients who receive highly emetogenic chemotherapy. National Cancer Institute of Canada Clinical Trials Group.  Academic Article
• Use of granulocyte colony-stimulating factor (G-CSF) in patients receiving myelosuppressive chemotherapy for the treatment of cancer. Provincial Systemic Treatment Disease Site Group.  Academic Article