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Urine biomarkers of acute kidney injury in...
Journal article

Urine biomarkers of acute kidney injury in noncritically ill, hospitalized children treated with chemotherapy

Abstract

BACKGROUND: Cisplatin (Cis), carboplatin (Carb), and ifosfamide (Ifos) are common nephrotoxic chemotherapies. Biomarkers of tubular injury may allow for early acute kidney injury (AKI) diagnosis. PROCEDURE: We performed a two-center (Canada, United States) pilot study to prospectively measure serum creatinine (SCr), urine neutrophil gelatinase-associated lipocalin (NGAL), and interleukin-18 (IL-18) in children receiving Cis/Carb (27 episodes), …

Authors

Sterling M; Al‐Ismaili Z; McMahon KR; Piccioni M; Pizzi M; Mottes T; Lands LC; Abish S; Fleming AJ; Bennett MR

Journal

Pediatric Blood & Cancer, Vol. 64, No. 10,

Publisher

Wiley

Publication Date

October 2017

DOI

10.1002/pbc.26538

ISSN

1545-5009